(52 nodes) Pyridoxal phosphate-dependent transferase network (Poecilia latipinna)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	etnppl	Ethanolamine-phosphate phospho-lyase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (478 aa)
	alas2	5-aminolevulinate synthase. (588 aa)
	GOT1	Aspartate aminotransferase. (410 aa)
	kyat1	Kynurenine aminotransferase 1. (444 aa)
	gad1	Glutamate decarboxylase 1a. (596 aa)
	hdc	Histidine decarboxylase. (644 aa)
	LOC106937586	Serine palmitoyltransferase, long chain base subunit 2a. (877 aa)
	MOCOS	Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. (837 aa)
	ddc	Dopa decarboxylase. (477 aa)
	sgpl1	Sphingosine-1-phosphate lyase 1. (565 aa)
	LOC106936335	SHMT domain-containing protein. (501 aa)
	LOC106945047	1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional). (557 aa)
	alas1	5-aminolevulinate synthase. (623 aa)
	abat	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (500 aa)
	scly	Selenocysteine lyase. (469 aa)
	phykpl	5-phosphohydroxy-L-lysine phospho-lyase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (449 aa)
	agxt2	Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (517 aa)
	LOC106963118	Uncharacterized protein. (444 aa)
	psat1	Phosphoserine aminotransferase. (360 aa)
	oat	Ornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (456 aa)
	kynu	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. (463 aa)
	LOC106937637	Aminotran_1_2 domain-containing protein. (473 aa)
	LOC106934637	Serine--pyruvate aminotransferase. (374 aa)
	nfs1	NFS1 cysteine desulfurase. (449 aa)
	kyat3	Kynurenine aminotransferase 3. (448 aa)
	ppp1r16a	Si:ch211-217a12.1. (1000 aa)
	LOC106941463	Tyrosine aminotransferase. (278 aa)
	LOC106955450	Aminotran_1_2 domain-containing protein. (493 aa)
	got2	Aspartate aminotransferase. (428 aa)
	shmt1	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (482 aa)
	LOC106961604	Serine hydroxymethyltransferase 1 (soluble). (445 aa)
	LOC106958903	Glutamic pyruvate transaminase (alanine aminotransferase) 2, like. (528 aa)
	SHMT2	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (504 aa)
	LOC106959593	Threonine aldolase 1. (418 aa)
	cth	Cystathionase (cystathionine gamma-lyase), like. (426 aa)
	sptlc2	Serine palmitoyltransferase, long chain base subunit 2b. (564 aa)
	LOC106954229	Uncharacterized protein. (511 aa)
	GADL1	Glutamate decarboxylase like 1. (488 aa)
	LOC106947629	Cysteine sulfinic acid decarboxylase. (522 aa)
	LOC106959721	Serine--pyruvate aminotransferase. (406 aa)
	ENSPLAP00000008282	Aminotran_1_2 domain-containing protein. (336 aa)
	gad2	Glutamate decarboxylase 2. (598 aa)
	got1	Aspartate aminotransferase. (410 aa)
	gcat	Glycine C-acetyltransferase. (427 aa)
	LOC106943727	Uncharacterized protein. (105 aa)
	pdxdc1	Pyridoxal-dependent decarboxylase domain containing 1. (797 aa)
	gldc	Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. (1039 aa)
	aadat	Aminoadipate aminotransferase. (425 aa)
	LOC106943916	Serine palmitoyltransferase, long chain base subunit 1. (317 aa)
	sepsecs	O-phosphoseryl-tRNA(Sec) selenium transferase; Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl- tRNA(Sec) required for selenoprotein biosynthesis. (485 aa)
	LOC106937595	Aminotran_1_2 domain-containing protein. (397 aa)
	ENSPLAP00000001070	Aminotran_1_2 domain-containing protein. (434 aa)

Your Current Organism:

Poecilia latipinna

NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPLAP00000001070	GADL1	ENSPLAP00000001070	ENSPLAP00000011425	Aminotran_1_2 domain-containing protein.	Glutamate decarboxylase like 1.	0.449
ENSPLAP00000001070	GOT1	ENSPLAP00000001070	ENSPLAP00000030858	Aminotran_1_2 domain-containing protein.	Aspartate aminotransferase.	0.928
ENSPLAP00000001070	LOC106934637	ENSPLAP00000001070	ENSPLAP00000017812	Aminotran_1_2 domain-containing protein.	Serine--pyruvate aminotransferase.	0.938
ENSPLAP00000001070	LOC106936335	ENSPLAP00000001070	ENSPLAP00000027048	Aminotran_1_2 domain-containing protein.	SHMT domain-containing protein.	0.560
ENSPLAP00000001070	LOC106937595	ENSPLAP00000001070	ENSPLAP00000001100	Aminotran_1_2 domain-containing protein.	Aminotran_1_2 domain-containing protein.	0.899
ENSPLAP00000001070	LOC106941463	ENSPLAP00000001070	ENSPLAP00000015398	Aminotran_1_2 domain-containing protein.	Tyrosine aminotransferase.	0.560
ENSPLAP00000001070	LOC106947629	ENSPLAP00000001070	ENSPLAP00000010407	Aminotran_1_2 domain-containing protein.	Cysteine sulfinic acid decarboxylase.	0.449
ENSPLAP00000001070	LOC106954229	ENSPLAP00000001070	ENSPLAP00000011477	Aminotran_1_2 domain-containing protein.	Uncharacterized protein.	0.449
ENSPLAP00000001070	LOC106955450	ENSPLAP00000001070	ENSPLAP00000014528	Aminotran_1_2 domain-containing protein.	Aminotran_1_2 domain-containing protein.	0.894
ENSPLAP00000001070	LOC106958903	ENSPLAP00000001070	ENSPLAP00000013033	Aminotran_1_2 domain-containing protein.	Glutamic pyruvate transaminase (alanine aminotransferase) 2, like.	0.901
ENSPLAP00000001070	LOC106959593	ENSPLAP00000001070	ENSPLAP00000012235	Aminotran_1_2 domain-containing protein.	Threonine aldolase 1.	0.683
ENSPLAP00000001070	LOC106959721	ENSPLAP00000001070	ENSPLAP00000009171	Aminotran_1_2 domain-containing protein.	Serine--pyruvate aminotransferase.	0.938
ENSPLAP00000001070	LOC106961604	ENSPLAP00000001070	ENSPLAP00000013185	Aminotran_1_2 domain-containing protein.	Serine hydroxymethyltransferase 1 (soluble).	0.560
ENSPLAP00000001070	LOC106963118	ENSPLAP00000001070	ENSPLAP00000022163	Aminotran_1_2 domain-containing protein.	Uncharacterized protein.	0.449
ENSPLAP00000001070	MOCOS	ENSPLAP00000001070	ENSPLAP00000028243	Aminotran_1_2 domain-containing protein.	Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.	0.579
ENSPLAP00000001070	SHMT2	ENSPLAP00000001070	ENSPLAP00000012948	Aminotran_1_2 domain-containing protein.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.560
ENSPLAP00000001070	aadat	ENSPLAP00000001070	ENSPLAP00000003040	Aminotran_1_2 domain-containing protein.	Aminoadipate aminotransferase.	0.639
ENSPLAP00000001070	abat	ENSPLAP00000001070	ENSPLAP00000025183	Aminotran_1_2 domain-containing protein.	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.637
ENSPLAP00000001070	agxt2	ENSPLAP00000001070	ENSPLAP00000022349	Aminotran_1_2 domain-containing protein.	Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.934
ENSPLAP00000001070	cth	ENSPLAP00000001070	ENSPLAP00000012230	Aminotran_1_2 domain-containing protein.	Cystathionase (cystathionine gamma-lyase), like.	0.690