(17 nodes) Thioredoxin, conserved site network (Poecilia latipinna)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	p4hb	Protein disulfide-isomerase. (509 aa)
	pdia5	Protein disulfide isomerase family A, member 5. (525 aa)
	txn2	Thioredoxin 2. (168 aa)
	LOC106951845	Protein disulfide-isomerase. (488 aa)
	pdia3	Protein disulfide-isomerase. (495 aa)
	dnajc10	DnaJ (Hsp40) homolog, subfamily C, member 10. (807 aa)
	ENSPLAP00000003448	Thioredoxin domain-containing protein. (147 aa)
	txndc12	Thioredoxin domain containing 12 (endoplasmic reticulum). (180 aa)
	TMX3	Thioredoxin related transmembrane protein 3. (450 aa)
	LOC106942385	Thioredoxin domain-containing protein; Belongs to the protein disulfide isomerase family. (287 aa)
	txndc5	Thioredoxin domain containing 5; Belongs to the protein disulfide isomerase family. (412 aa)
	pdia6	Protein disulfide isomerase family A, member 6; Belongs to the protein disulfide isomerase family. (440 aa)
	LOC106944735	Thioredoxin; Belongs to the thioredoxin family. (107 aa)
	LOC106944734	Thioredoxin; Belongs to the thioredoxin family. (100 aa)
	pdia4	Protein disulfide-isomerase A4; Belongs to the protein disulfide isomerase family. (641 aa)
	LOC106938355	NME/NM23 family member 8; Belongs to the NDK family. (530 aa)
	tmx1	Thioredoxin-related transmembrane protein 1. (308 aa)

Your Current Organism:

Poecilia latipinna

NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPLAP00000003448	LOC106942385	ENSPLAP00000003448	ENSPLAP00000029162	Thioredoxin domain-containing protein.	Thioredoxin domain-containing protein; Belongs to the protein disulfide isomerase family.	0.888
ENSPLAP00000003448	LOC106944735	ENSPLAP00000003448	ENSPLAP00000017324	Thioredoxin domain-containing protein.	Thioredoxin; Belongs to the thioredoxin family.	0.416
ENSPLAP00000003448	dnajc10	ENSPLAP00000003448	ENSPLAP00000004229	Thioredoxin domain-containing protein.	DnaJ (Hsp40) homolog, subfamily C, member 10.	0.793
ENSPLAP00000003448	pdia3	ENSPLAP00000003448	ENSPLAP00000004297	Thioredoxin domain-containing protein.	Protein disulfide-isomerase.	0.728
ENSPLAP00000003448	pdia4	ENSPLAP00000003448	ENSPLAP00000016240	Thioredoxin domain-containing protein.	Protein disulfide-isomerase A4; Belongs to the protein disulfide isomerase family.	0.728
ENSPLAP00000003448	pdia5	ENSPLAP00000003448	ENSPLAP00000007504	Thioredoxin domain-containing protein.	Protein disulfide isomerase family A, member 5.	0.650
ENSPLAP00000003448	pdia6	ENSPLAP00000003448	ENSPLAP00000019475	Thioredoxin domain-containing protein.	Protein disulfide isomerase family A, member 6; Belongs to the protein disulfide isomerase family.	0.896
ENSPLAP00000003448	txndc5	ENSPLAP00000003448	ENSPLAP00000021348	Thioredoxin domain-containing protein.	Thioredoxin domain containing 5; Belongs to the protein disulfide isomerase family.	0.871
LOC106938355	dnajc10	ENSPLAP00000014155	ENSPLAP00000004229	NME/NM23 family member 8; Belongs to the NDK family.	DnaJ (Hsp40) homolog, subfamily C, member 10.	0.530
LOC106938355	txn2	ENSPLAP00000014155	ENSPLAP00000007485	NME/NM23 family member 8; Belongs to the NDK family.	Thioredoxin 2.	0.893
LOC106942385	ENSPLAP00000003448	ENSPLAP00000029162	ENSPLAP00000003448	Thioredoxin domain-containing protein; Belongs to the protein disulfide isomerase family.	Thioredoxin domain-containing protein.	0.888
LOC106942385	LOC106944734	ENSPLAP00000029162	ENSPLAP00000017316	Thioredoxin domain-containing protein; Belongs to the protein disulfide isomerase family.	Thioredoxin; Belongs to the thioredoxin family.	0.496
LOC106942385	LOC106944735	ENSPLAP00000029162	ENSPLAP00000017324	Thioredoxin domain-containing protein; Belongs to the protein disulfide isomerase family.	Thioredoxin; Belongs to the thioredoxin family.	0.554
LOC106942385	dnajc10	ENSPLAP00000029162	ENSPLAP00000004229	Thioredoxin domain-containing protein; Belongs to the protein disulfide isomerase family.	DnaJ (Hsp40) homolog, subfamily C, member 10.	0.793
LOC106942385	pdia3	ENSPLAP00000029162	ENSPLAP00000004297	Thioredoxin domain-containing protein; Belongs to the protein disulfide isomerase family.	Protein disulfide-isomerase.	0.728
LOC106942385	pdia4	ENSPLAP00000029162	ENSPLAP00000016240	Thioredoxin domain-containing protein; Belongs to the protein disulfide isomerase family.	Protein disulfide-isomerase A4; Belongs to the protein disulfide isomerase family.	0.728
LOC106942385	pdia5	ENSPLAP00000029162	ENSPLAP00000007504	Thioredoxin domain-containing protein; Belongs to the protein disulfide isomerase family.	Protein disulfide isomerase family A, member 5.	0.650
LOC106942385	pdia6	ENSPLAP00000029162	ENSPLAP00000019475	Thioredoxin domain-containing protein; Belongs to the protein disulfide isomerase family.	Protein disulfide isomerase family A, member 6; Belongs to the protein disulfide isomerase family.	0.896
LOC106942385	txn2	ENSPLAP00000029162	ENSPLAP00000007485	Thioredoxin domain-containing protein; Belongs to the protein disulfide isomerase family.	Thioredoxin 2.	0.479
LOC106942385	txndc5	ENSPLAP00000029162	ENSPLAP00000021348	Thioredoxin domain-containing protein; Belongs to the protein disulfide isomerase family.	Thioredoxin domain containing 5; Belongs to the protein disulfide isomerase family.	0.871