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LOC106939076 LOC106939076 ENSPLAP00000006347 ENSPLAP00000006347 LOC106959835 LOC106959835 LOC106964583 LOC106964583 ENSPLAP00000004498 ENSPLAP00000004498 mdm2 mdm2 LOC106947336 LOC106947336 ENSPLAP00000000716 ENSPLAP00000000716 LOC106955966 LOC106955966 cacng4 cacng4 PRKCA PRKCA LOC106938420 LOC106938420 LOC106957043 LOC106957043 LOC106938978 LOC106938978 LOC106934908 LOC106934908 ENSPLAP00000026113 ENSPLAP00000026113 PRKCB PRKCB grip1 grip1 LOC106935035 LOC106935035 tspan6 tspan6 GRIA2 GRIA2 LOC106950382 LOC106950382 ENSPLAP00000022549 ENSPLAP00000022549 LOC106937876 LOC106937876 LOC106954491 LOC106954491 LOC106936764 LOC106936764 tspan7 tspan7 cacng2 cacng2 ENSPLAP00000016075 ENSPLAP00000016075 ENSPLAP00000014716 ENSPLAP00000014716 ap2s1 ap2s1 pick1 pick1 nsf nsf ENSPLAP00000012518 ENSPLAP00000012518 ap2m1 ap2m1 CACNG2 CACNG2 ENSPLAP00000011191 ENSPLAP00000011191 cacng3 cacng3 LOC106939953 LOC106939953 ENSPLAP00000009487 ENSPLAP00000009487 LOC106947084 LOC106947084 LOC106945113 LOC106945113
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC106939076AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (938 aa)
ENSPLAP00000006347PBPe domain-containing protein; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (281 aa)
LOC106959835Uncharacterized protein. (877 aa)
LOC106964583Glutamate receptor, ionotropic, AMPA 1a. (598 aa)
ENSPLAP00000004498Protein kinase domain-containing protein. (312 aa)
mdm2MDM2 proto-oncogene; Belongs to the MDM2/MDM4 family. (471 aa)
LOC106947336Glutamate receptor interacting protein 2b. (960 aa)
ENSPLAP00000000716Uncharacterized protein. (143 aa)
LOC106955966Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (474 aa)
cacng4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (333 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (671 aa)
LOC106938420Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (694 aa)
LOC106957043Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (680 aa)
LOC106938978Uncharacterized protein. (628 aa)
LOC106934908Glutamate receptor interacting protein 2a. (949 aa)
ENSPLAP00000026113AGC-kinase C-terminal domain-containing protein. (55 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (680 aa)
grip1Glutamate receptor interacting protein 1. (953 aa)
LOC106935035Alpha_adaptinC2 domain-containing protein. (574 aa)
tspan6Tetraspanin. (251 aa)
GRIA2Glutamate ionotropic receptor AMPA type subunit 2. (806 aa)
LOC106950382Tetraspanin. (250 aa)
ENSPLAP00000022549Uncharacterized protein. (79 aa)
LOC106937876AP complex subunit beta. (918 aa)
LOC106954491Uncharacterized protein. (858 aa)
LOC106936764Uncharacterized protein. (786 aa)
tspan7Tetraspanin. (244 aa)
cacng2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (317 aa)
ENSPLAP00000016075Uncharacterized protein. (95 aa)
ENSPLAP00000014716Adaptin_N domain-containing protein. (211 aa)
ap2s1AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (142 aa)
pick1Protein interacting with prkca 1. (409 aa)
nsfUncharacterized protein. (734 aa)
ENSPLAP00000012518CaMKII_AD domain-containing protein. (171 aa)
ap2m1AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] (358 aa)
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (231 aa)
ENSPLAP00000011191Phorbol-ester/DAG-type domain-containing protein. (55 aa)
cacng3Calcium voltage-gated channel auxiliary subunit gamma 3. (315 aa)
LOC106939953Protein kinase C, beta a; Belongs to the protein kinase superfamily. (428 aa)
ENSPLAP00000009487AGC-kinase C-terminal domain-containing protein. (59 aa)
LOC106947084Uncharacterized protein. (884 aa)
LOC106945113N-ethylmaleimide-sensitive factor b; Belongs to the AAA ATPase family. (677 aa)
Your Current Organism:
Poecilia latipinna
NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly
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