STRINGSTRING
aqr aqr rfc3 rfc3 LOC106960140 LOC106960140 rfc2 rfc2 cul4b cul4b ercc6 ercc6 polr2c polr2c ENSPLAP00000015559 ENSPLAP00000015559 rfc4 rfc4 LOC106942419 LOC106942419 RCBTB1 RCBTB1 rpap3 rpap3 prpf19 prpf19 rbx1 rbx1 cops2 cops2 polr2d polr2d ENSPLAP00000013662 ENSPLAP00000013662 ddb1 ddb1 LOC106957493 LOC106957493 LOC106942557 LOC106942557 ENSPLAP00000013068 ENSPLAP00000013068 bivm bivm atad5 atad5 rpa3 rpa3 ENSPLAP00000012461 ENSPLAP00000012461 LOC106954174 LOC106954174 LOC106958966 LOC106958966 ube2n ube2n LOC106938509 LOC106938509 POLR2E POLR2E pold1 pold1 polr2j polr2j sumo2 sumo2 usp7 usp7 tfpt tfpt LOC106964401 LOC106964401 meiob meiob pold4 pold4 xpa xpa pole2 pole2 gps1 gps1 LOC106956472 LOC106956472 pold3 pold3 cops8 cops8 LOC106945531 LOC106945531 LOC106948335 LOC106948335 ercc5 ercc5 polr2l polr2l LOC106943626 LOC106943626 tcea1 tcea1 LOC106943640 LOC106943640 ino80c ino80c ino80e ino80e LOC106943710 LOC106943710 ZNF830 ZNF830 actr5 actr5 nfrkb nfrkb pias1 pias1 pold2 pold2 polr2a polr2a ppp1r42 ppp1r42 xrcc1 xrcc1 ENSPLAP00000005122 ENSPLAP00000005122 ube2i ube2i pole3 pole3 LOC106964619 LOC106964619 COPS6 COPS6 LOC106956601 LOC106956601 gtf2h1 gtf2h1 rpa1 rpa1 cdk7 cdk7 LOC106943827 LOC106943827 RAD23B RAD23B ino80b ino80b ddb2 ddb2 pole pole ENSPLAP00000002262 ENSPLAP00000002262 cops7a cops7a YY1 YY1 ccnh ccnh pcna pcna LOC106953687 LOC106953687 cops3 cops3 mcrs1 mcrs1 LOC106953745 LOC106953745 LOC106953803 LOC106953803 polr2f polr2f parp1 parp1 polr2b polr2b polr2h polr2h LOC106943114 LOC106943114 uvssa uvssa lig3 lig3 rfc1 rfc1 ercc4 ercc4 nrde2 nrde2 xab2 xab2 ercc8 ercc8 ino80d ino80d rpa2 rpa2 polk polk lig1 lig1 sumo1 sumo1 gtf2h3 gtf2h3 LOC106941517 LOC106941517 ruvbl1 ruvbl1 ENSPLAP00000028220 ENSPLAP00000028220 usp40 usp40 LOC106960917 LOC106960917 uba52 uba52 wbp1 wbp1 LOC106951593 LOC106951593 ENSPLAP00000027155 ENSPLAP00000027155 LOC106952805 LOC106952805 chd1l chd1l LOC106963705 LOC106963705 LOC106948217 LOC106948217 parp3 parp3 rps27a rps27a mnat1 mnat1 gtf2h4 gtf2h4 polr2i polr2i ppie ppie cul4a cul4a ube2v2 ube2v2 LOC106950980 LOC106950980 LOC106952373 LOC106952373 rnf111 rnf111 actb actb LOC106952964 LOC106952964 cops5 cops5 tceanc tceanc rad23a rad23a rfc5 rfc5 cops4 cops4 actr8 actr8 LOC106936495 LOC106936495 LOC106945923 LOC106945923 ENSPLAP00000020248 ENSPLAP00000020248 ercc2 ercc2 wdr76 wdr76 cetn3 cetn3 ENSPLAP00000018761 ENSPLAP00000018761 pole4 pole4 LOC106957973 LOC106957973 tceanc2 tceanc2 gtf2h5 gtf2h5 polr2g polr2g ercc3 ercc3 ercc1 ercc1 xpc xpc LOC106959376 LOC106959376
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
aqrAquarius intron-binding spliceosomal factor. (1468 aa)
rfc3Replication factor C (activator 1) 3. (356 aa)
LOC106960140ATPase family AAA domain containing 5a. (1813 aa)
rfc2Replication factor C (activator 1) 2. (357 aa)
cul4bCullin 4B; Belongs to the cullin family. (868 aa)
ercc6Excision repair cross-complementation group 6. (1411 aa)
polr2cPolymerase (RNA) II (DNA directed) polypeptide C. (275 aa)
ENSPLAP00000015559Ubiquitin-like domain-containing protein. (93 aa)
rfc4Replication factor C (activator 1) 4. (357 aa)
LOC106942419COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis). (349 aa)
RCBTB1RCC1 and BTB domain containing protein 1. (531 aa)
rpap3RNA polymerase II associated protein 3. (636 aa)
prpf19Pre-mRNA processing factor 19. (505 aa)
rbx1Ring-box 1, E3 ubiquitin protein ligase. (108 aa)
cops2COP9 signalosome subunit 2. (443 aa)
polr2dPolymerase (RNA) II (DNA directed) polypeptide D. (144 aa)
ENSPLAP00000013662E1A binding protein p300 b. (2525 aa)
ddb1Damage-specific DNA binding protein 1. (1139 aa)
LOC106957493Small ubiquitin-related modifier. (94 aa)
LOC106942557Uncharacterized protein; Belongs to the actin family. (421 aa)
ENSPLAP00000013068Uncharacterized protein. (230 aa)
bivmBasic, immunoglobulin-like variable motif containing. (502 aa)
atad5AAA domain-containing protein. (802 aa)
rpa3Replication protein A3. (122 aa)
ENSPLAP00000012461Rad60-SLD domain-containing protein. (142 aa)
LOC106954174Small ubiquitin-related modifier. (96 aa)
LOC106958966Si:ch73-290k24.6. (746 aa)
ube2nUbiquitin conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
LOC106938509kxDL motif-containing protein 1-like. (185 aa)
POLR2ERNA polymerase II subunit E. (210 aa)
pold1DNA polymerase. (1105 aa)
polr2jPolymerase (RNA) II (DNA directed) polypeptide J. (117 aa)
sumo2Small ubiquitin-related modifier. (95 aa)
usp7Ubiquitin specific peptidase 7 (herpes virus-associated); Belongs to the peptidase C19 family. (1184 aa)
tfptTCF3 (E2A) fusion partner. (199 aa)
LOC106964401High mobility group nucleosome binding domain 6. (97 aa)
meiobMethionine sulfoxide reductase B1b. (284 aa)
pold4Si:dkey-28b4.7. (108 aa)
xpaXeroderma pigmentosum, complementation group A. (275 aa)
pole2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (528 aa)
gps1G protein pathway suppressor 1. (486 aa)
LOC106956472Transcription elongation factor A (SII), 3. (742 aa)
pold3Polymerase (DNA-directed), delta 3, accessory subunit. (437 aa)
cops8COP9 signalosome subunit 8. (187 aa)
LOC106945531Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2. (527 aa)
LOC106948335Uncharacterized protein. (375 aa)
ercc5Excision repair cross-complementation group 5. (1095 aa)
polr2lPolymerase (RNA) II (DNA directed) polypeptide L. (67 aa)
LOC106943626Uncharacterized protein. (493 aa)
tcea1Transcription elongation factor A (SII), 1. (311 aa)
LOC106943640General transcription factor IIH, polypeptide 2. (275 aa)
ino80cINO80 complex subunit C. (204 aa)
ino80eINO80 complex subunit E. (256 aa)
LOC106943710UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (151 aa)
ZNF830Zinc finger protein 830. (336 aa)
actr5Actin related protein 5; Belongs to the actin family. (603 aa)
nfrkbNuclear factor related to kappaB binding protein. (1277 aa)
pias1Protein inhibitor of activated STAT, 1b. (656 aa)
pold2Polymerase (DNA directed), delta 2, regulatory subunit. (471 aa)
polr2aDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1907 aa)
ppp1r42Protein phosphatase 1, regulatory subunit 42. (330 aa)
xrcc1X-ray repair complementing defective repair in Chinese hamster cells 1. (627 aa)
ENSPLAP00000005122Uncharacterized protein. (139 aa)
ube2iUbiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
pole3Polymerase (DNA directed), epsilon 3 (p17 subunit). (150 aa)
LOC106964619RPA_C domain-containing protein. (255 aa)
COPS6COP9 signalosome subunit 6. (316 aa)
LOC106956601KxDL motif containing 1. (185 aa)
gtf2h1General transcription factor IIH, polypeptide 1. (550 aa)
rpa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (600 aa)
cdk7Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (360 aa)
LOC106943827UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (102 aa)
RAD23BRAD23 homolog B, nucleotide excision repair protein. (393 aa)
ino80bINO80 complex subunit B. (339 aa)
ddb2Damage-specific DNA binding protein 2. (485 aa)
poleDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2016 aa)
ENSPLAP00000002262Uncharacterized protein; Belongs to the actin family. (315 aa)
cops7aCOP9 constitutive photomorphogenic homolog subunit 7A. (268 aa)
YY1YY1 transcription factor b. (367 aa)
ccnhCyclin H; Belongs to the cyclin family. (319 aa)
pcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (310 aa)
LOC106953687Von Willebrand factor A domain containing 5B2. (1012 aa)
cops3COP9 signalosome subunit 3. (423 aa)
mcrs1Microspherule protein 1. (466 aa)
LOC106953745Cyclin H; Belongs to the cyclin family. (318 aa)
LOC106953803UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (153 aa)
polr2fPolymerase (RNA) II (DNA directed) polypeptide F. (127 aa)
parp1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1015 aa)
polr2bDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
polr2hDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
LOC106943114General transcription factor IIH, polypeptide 2. (181 aa)
uvssaUV-stimulated scaffold protein A. (687 aa)
lig3DNA ligase. (924 aa)
rfc1Replication factor C subunit 1. (1147 aa)
ercc4Excision repair cross-complementation group 4. (888 aa)
nrde2NRDE-2, necessary for RNA interference, domain containing. (1205 aa)
xab2XPA binding protein 2. (849 aa)
ercc8Excision repair cross-complementation group 8. (401 aa)
ino80dINO80 complex subunit Da. (1006 aa)
rpa2Replication protein A2. (278 aa)
polkPolymerase (DNA directed) kappa. (866 aa)
lig1DNA ligase. (1002 aa)
sumo1Small ubiquitin-related modifier. (101 aa)
gtf2h3General transcription factor IIH, polypeptide 3. (300 aa)
LOC106941517Poly [ADP-ribose] polymerase. (385 aa)
ruvbl1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
ENSPLAP00000028220Uncharacterized protein. (94 aa)
usp40Ubiquitin specific peptidase 40; Belongs to the peptidase C19 family. (1290 aa)
LOC106960917Potassium channel tetramerization domain containing 2. (271 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
wbp1Uncharacterized protein. (486 aa)
LOC106951593Si:ch73-1a9.3. (79 aa)
ENSPLAP00000027155Si:cabz01080528.1. (686 aa)
LOC106952805Small ubiquitin-related modifier. (103 aa)
chd1lChromodomain helicase DNA binding protein 1-like. (1020 aa)
LOC106963705YY1 transcription factor. (357 aa)
LOC106948217Centrin 4. (171 aa)
parp3Poly [ADP-ribose] polymerase. (522 aa)
rps27aRibosomal protein S27a. (156 aa)
mnat1MNAT1 component of CDK activating kinase. (296 aa)
gtf2h4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (419 aa)
polr2iDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (126 aa)
ppiePeptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily. (301 aa)
cul4aCullin 4A; Belongs to the cullin family. (753 aa)
ube2v2Ubiquitin-conjugating enzyme E2 variant 2. (145 aa)
LOC106950980Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1. (531 aa)
LOC106952373Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (637 aa)
rnf111Ring finger protein 111. (1022 aa)
actbUncharacterized protein. (389 aa)
LOC106952964Transcription elongation factor A (SII), 2. (302 aa)
cops5COP9 signalosome subunit 5. (336 aa)
tceancUncharacterized protein. (355 aa)
rad23aRAD23 homolog A, nucleotide excision repair protein a. (365 aa)
rfc5Replication factor C (activator 1) 5. (335 aa)
cops4COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis). (406 aa)
actr8Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily. (646 aa)
LOC106936495Ubiquitinyl hydrolase 1. (776 aa)
LOC106945923Uncharacterized protein. (375 aa)
ENSPLAP00000020248Uncharacterized protein. (68 aa)
ercc2Excision repair cross-complementation group 2. (760 aa)
wdr76WD repeat-containing protein 76; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. Belongs to the WD repeat DDB2/WDR76 family. (540 aa)
cetn3Uncharacterized protein. (166 aa)
ENSPLAP00000018761SCY domain-containing protein. (117 aa)
pole4Polymerase (DNA-directed), epsilon 4, accessory subunit. (133 aa)
LOC106957973PHD finger protein 3. (1653 aa)
tceanc2Uncharacterized protein. (207 aa)
gtf2h5General transcription factor IIH, polypeptide 5. (71 aa)
polr2gPolymerase (RNA) II (DNA directed) polypeptide G-like. (177 aa)
ercc3Excision repair cross-complementation group 3. (771 aa)
ercc1Excision repair cross-complementation group 1. (356 aa)
xpcXeroderma pigmentosum, complementation group C. (898 aa)
LOC106959376Protein inhibitor of activated STAT, 1a. (677 aa)
Your Current Organism:
Poecilia latipinna
NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly
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