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sdhd sdhd adhfe1 adhfe1 fam114a1 fam114a1 OGDH OGDH LOC106945413 LOC106945413 LOC106937574 LOC106937574 LOC106955361 LOC106955361 LOC106946097 LOC106946097 LOC106934742 LOC106934742 ENSPLAP00000028491 ENSPLAP00000028491 pdk1 pdk1 sdhc sdhc LOC106940840 LOC106940840 LOC106957330 LOC106957330 ENSPLAP00000026564 ENSPLAP00000026564 LOC106937029 LOC106937029 ppard ppard pnkd pnkd LOC106935930 LOC106935930 LDHA LDHA idh3g idh3g pdk4 pdk4 LOC106934392 LOC106934392 LOC106952359 LOC106952359 LOC106952394 LOC106952394 d2hgdh d2hgdh pdhb pdhb suclg1 suclg1 me1 me1 GLO1 GLO1 LOC106937541 LOC106937541 LOC106953397 LOC106953397 mpc2 mpc2 cs cs dlat dlat ogdh ogdh LOC106942426 LOC106942426 gstz1 gstz1 LACTB2 LACTB2 sdha sdha ACO2 ACO2 sucla2 sucla2 SDHB SDHB pdpr pdpr pdp2 pdp2 HAGHL HAGHL l2hgdh l2hgdh dlst dlst pdhx pdhx mpc1 mpc1 idh2 idh2 dld dld me2 me2 ENSPLAP00000000767 ENSPLAP00000000767 LOC106958358 LOC106958358 ENSPLAP00000000951 ENSPLAP00000000951 LOC106953705 LOC106953705 suclg2 suclg2 LOC106951907 LOC106951907 pdk3 pdk3 LOC106946434 LOC106946434 DLST DLST ENSPLAP00000005060 ENSPLAP00000005060 idh3a idh3a ENSPLAP00000006226 ENSPLAP00000006226 pdp1 pdp1 idh3b idh3b LOC106938657 LOC106938657 mblac2 mblac2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
sdhdSuccinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (166 aa)
adhfe1Alcohol dehydrogenase iron containing 1. (433 aa)
fam114a1Family with sequence similarity 114 member A1. (594 aa)
OGDHOxoglutarate dehydrogenase. (1044 aa)
LOC106945413Protein-serine/threonine kinase. (408 aa)
LOC106937574PNKD metallo-beta-lactamase domain containing. (265 aa)
LOC106955361Malic enzyme. (618 aa)
LOC106946097L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (355 aa)
LOC106934742Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (400 aa)
ENSPLAP00000028491Malate dehydrogenase. (274 aa)
pdk1Protein-serine/threonine kinase. (407 aa)
sdhcSuccinate dehydrogenase complex, subunit C, integral membrane protein. (169 aa)
LOC106940840L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (334 aa)
LOC106957330Hydroxyacylglutathione hydrolase. (309 aa)
ENSPLAP00000026564Fumarylacetoacetate hydrolase domain containing 1. (218 aa)
LOC106937029Si:ch211-15p9.2. (514 aa)
ppardPeroxisome proliferator-activated receptor delta b. (508 aa)
pnkdSi:ch73-71c20.5. (150 aa)
LOC106935930Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (782 aa)
LDHAL-lactate dehydrogenase A chain. (332 aa)
idh3gIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (392 aa)
pdk4Protein-serine/threonine kinase. (410 aa)
LOC106934392Nicotinamide nucleotide transhydrogenase 2. (956 aa)
LOC106952359Uncharacterized protein. (608 aa)
LOC106952394Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (390 aa)
d2hgdhD-2-hydroxyglutarate dehydrogenase. (550 aa)
pdhbPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (360 aa)
suclg1Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. (330 aa)
me1Malic enzyme. (588 aa)
GLO1Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (180 aa)
LOC106937541Voltage-dependent anion channel 1. (283 aa)
LOC106953397Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (452 aa)
mpc2Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (123 aa)
csCitrate synthase; Belongs to the citrate synthase family. (434 aa)
dlatAcetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (643 aa)
ogdhOxoglutarate (alpha-ketoglutarate) dehydrogenase b (lipoamide). (1017 aa)
LOC106942426Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (179 aa)
gstz1Glutathione S-transferase zeta 1; Belongs to the GST superfamily. (220 aa)
LACTB2Lactamase beta 2. (287 aa)
sdhaSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (663 aa)
ACO2Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (781 aa)
sucla2Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (478 aa)
SDHBSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (283 aa)
pdprPyruvate dehydrogenase phosphatase regulatory subunit. (889 aa)
pdp2Putative pyruvate dehydrogenase phosphatase isoenzyme 2. (527 aa)
HAGHLHydroxyacylglutathione hydrolase like. (290 aa)
l2hgdhL-2-hydroxyglutarate dehydrogenase. (447 aa)
dlstDihydrolipoamide S-succinyltransferase. (458 aa)
pdhxDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (474 aa)
mpc1Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (108 aa)
idh2Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (453 aa)
dldDihydrolipoamide dehydrogenase. (435 aa)
me2Malic enzyme. (582 aa)
ENSPLAP00000000767Fumarate hydratase. (482 aa)
LOC106958358Glutathione S-transferase rho; Belongs to the GST superfamily. (226 aa)
ENSPLAP00000000951Uncharacterized protein; Belongs to the GST superfamily. (215 aa)
LOC106953705L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (332 aa)
suclg2Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (431 aa)
LOC106951907Retinoid X receptor, alpha a. (459 aa)
pdk3Protein-serine/threonine kinase. (407 aa)
LOC106946434Nicotinamide nucleotide transhydrogenase. (1163 aa)
DLSTDihydrolipoamide S-succinyltransferase. (227 aa)
ENSPLAP000000050602Fe-2S ferredoxin-type domain-containing protein. (260 aa)
idh3aIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (362 aa)
ENSPLAP00000006226Uncharacterized protein. (128 aa)
pdp1Pyruvate dehyrogenase phosphatase catalytic subunit 1. (523 aa)
idh3bIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (386 aa)
LOC106938657Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (366 aa)
mblac2Metallo-beta-lactamase domain containing 2. (276 aa)
Your Current Organism:
Poecilia latipinna
NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly
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