(36 nodes) RNA Polymerase I Transcription Termination network (Poecilia latipinna)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

Your Input:
	polr2h	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
	taf1b	TATA box binding protein (Tbp)-associated factor, RNA polymerase I, B. (598 aa)
	polr2f	Polymerase (RNA) II (DNA directed) polypeptide F. (127 aa)
	LOC106953745	Cyclin H; Belongs to the cyclin family. (318 aa)
	ccnh	Cyclin H; Belongs to the cyclin family. (319 aa)
	LOC106943900	RNA polymerase I and III subunit C. (132 aa)
	cdk7	Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (360 aa)
	gtf2h1	General transcription factor IIH, polypeptide 1. (550 aa)
	polr1c	RNA polymerase I and III subunit C. (240 aa)
	LOC106943114	General transcription factor IIH, polypeptide 2. (181 aa)
	polr1a	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1689 aa)
	gtf2h3	General transcription factor IIH, polypeptide 3. (300 aa)
	taf1c	Uncharacterized protein. (927 aa)
	ENSPLAP00000028220	Uncharacterized protein. (94 aa)
	LOC106963658	Caveolae associated protein 1a. (375 aa)
	mnat1	MNAT1 component of CDK activating kinase. (296 aa)
	gtf2h4	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (419 aa)
	ENSPLAP00000024302	Uncharacterized protein. (284 aa)
	polr1b	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1134 aa)
	ttf1	Uncharacterized protein. (592 aa)
	LOC106943640	General transcription factor IIH, polypeptide 2. (275 aa)
	polr2l	Polymerase (RNA) II (DNA directed) polypeptide L. (67 aa)
	LOC106936429	Caveolae associated protein 1b. (469 aa)
	POLR2E	RNA polymerase II subunit E. (210 aa)
	tbp	TATA box binding protein. (304 aa)
	ENSPLAP00000012054	Uncharacterized protein. (229 aa)
	ubtf	Upstream binding transcription factor. (738 aa)
	LOC106960305	Upstream binding transcription factor, like. (738 aa)
	twistnb	Uncharacterized protein. (376 aa)
	taf1a	TATA box binding protein (TBP)-associated factor, RNA polymerase I, A. (430 aa)
	ercc3	Excision repair cross-complementation group 3. (771 aa)
	polr1e	RNA polymerase I subunit E. (415 aa)
	gtf2h5	General transcription factor IIH, polypeptide 5. (71 aa)
	cd3eap	CD3e molecule, epsilon associated protein. (337 aa)
	ercc2	Excision repair cross-complementation group 2. (760 aa)
	ENSPLAP00000020248	Uncharacterized protein. (68 aa)

Your Current Organism:

Poecilia latipinna

NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPLAP00000012054	ENSPLAP00000020248	ENSPLAP00000012054	ENSPLAP00000020248	Uncharacterized protein.	Uncharacterized protein.	0.955
ENSPLAP00000012054	ENSPLAP00000024302	ENSPLAP00000012054	ENSPLAP00000024302	Uncharacterized protein.	Uncharacterized protein.	0.713
ENSPLAP00000012054	ENSPLAP00000028220	ENSPLAP00000012054	ENSPLAP00000028220	Uncharacterized protein.	Uncharacterized protein.	0.852
ENSPLAP00000012054	LOC106943114	ENSPLAP00000012054	ENSPLAP00000031579	Uncharacterized protein.	General transcription factor IIH, polypeptide 2.	0.852
ENSPLAP00000012054	LOC106943640	ENSPLAP00000012054	ENSPLAP00000007711	Uncharacterized protein.	General transcription factor IIH, polypeptide 2.	0.852
ENSPLAP00000012054	LOC106943900	ENSPLAP00000012054	ENSPLAP00000002600	Uncharacterized protein.	RNA polymerase I and III subunit C.	0.870
ENSPLAP00000012054	LOC106953745	ENSPLAP00000012054	ENSPLAP00000000607	Uncharacterized protein.	Cyclin H; Belongs to the cyclin family.	0.854
ENSPLAP00000012054	LOC106960305	ENSPLAP00000012054	ENSPLAP00000013490	Uncharacterized protein.	Upstream binding transcription factor, like.	0.710
ENSPLAP00000012054	POLR2E	ENSPLAP00000012054	ENSPLAP00000011389	Uncharacterized protein.	RNA polymerase II subunit E.	0.966
ENSPLAP00000012054	ccnh	ENSPLAP00000012054	ENSPLAP00000001502	Uncharacterized protein.	Cyclin H; Belongs to the cyclin family.	0.854
ENSPLAP00000012054	cd3eap	ENSPLAP00000012054	ENSPLAP00000018970	Uncharacterized protein.	CD3e molecule, epsilon associated protein.	0.534
ENSPLAP00000012054	cdk7	ENSPLAP00000012054	ENSPLAP00000003235	Uncharacterized protein.	Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily.	0.833
ENSPLAP00000012054	ercc2	ENSPLAP00000012054	ENSPLAP00000020036	Uncharacterized protein.	Excision repair cross-complementation group 2.	0.949
ENSPLAP00000012054	ercc3	ENSPLAP00000012054	ENSPLAP00000017727	Uncharacterized protein.	Excision repair cross-complementation group 3.	0.960
ENSPLAP00000012054	gtf2h1	ENSPLAP00000012054	ENSPLAP00000003889	Uncharacterized protein.	General transcription factor IIH, polypeptide 1.	0.954
ENSPLAP00000012054	gtf2h3	ENSPLAP00000012054	ENSPLAP00000028969	Uncharacterized protein.	General transcription factor IIH, polypeptide 3.	0.960
ENSPLAP00000012054	gtf2h4	ENSPLAP00000012054	ENSPLAP00000025113	Uncharacterized protein.	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	0.956
ENSPLAP00000012054	gtf2h5	ENSPLAP00000012054	ENSPLAP00000018210	Uncharacterized protein.	General transcription factor IIH, polypeptide 5.	0.841
ENSPLAP00000012054	mnat1	ENSPLAP00000012054	ENSPLAP00000025502	Uncharacterized protein.	MNAT1 component of CDK activating kinase.	0.951
ENSPLAP00000012054	polr1a	ENSPLAP00000012054	ENSPLAP00000030338	Uncharacterized protein.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.849