(63 nodes) Tyrosine metabolism network (Poecilia latipinna)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	katnal2	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays. (423 aa)
	comtd1	Uncharacterized protein. (257 aa)
	spast	Spastin; Belongs to the AAA ATPase family. (547 aa)
	dct	Dopachrome tautomerase. (510 aa)
	fignl1	Fidgetin-like 1; Belongs to the AAA ATPase family. (626 aa)
	LOC106949400	Zgc:85789. (319 aa)
	dbh	Dopamine beta-hydroxylase (dopamine beta-monooxygenase). (598 aa)
	comt	Catechol-O-methyltransferase b. (265 aa)
	LOC106937588	PKS_ER domain-containing protein. (378 aa)
	LOC106957402	Monooxygenase, DBH-like 1, like. (501 aa)
	LOC106941463	Tyrosine aminotransferase. (278 aa)
	LOC106937590	PKS_ER domain-containing protein. (411 aa)
	LOC106939773	RNA binding motif protein 12B. (635 aa)
	gstz1	Glutathione S-transferase zeta 1; Belongs to the GST superfamily. (220 aa)
	ENSPLAP00000014107	Uncharacterized protein. (168 aa)
	got2	Aspartate aminotransferase. (428 aa)
	pnmt	Uncharacterized protein. (115 aa)
	LOC106961687	Zgc:77938. (382 aa)
	fign	Fidgetin; Belongs to the AAA ATPase family. (752 aa)
	LOC106964191	AAA domain-containing protein. (766 aa)
	ammecr1	AMMECR1 domain-containing protein. (329 aa)
	rbm12b	Zgc:153215. (414 aa)
	mif	Macrophage migration inhibitory factor. (115 aa)
	ENSPLAP00000006623	Uncharacterized protein. (80 aa)
	LOC106936599	Thioesterase superfamily member 6. (203 aa)
	got1	Aspartate aminotransferase. (410 aa)
	hpdl	4-hydroxyphenylpyruvate dioxygenase. (453 aa)
	LOC106947295	Amine oxidase. (554 aa)
	TPO	Thyroid peroxidase. (708 aa)
	LOC106953921	Amine oxidase. (687 aa)
	LOC106939924	Transmembrane O-methyltransferase. (259 aa)
	tyr	Tyrosinase. (540 aa)
	ddc	Dopa decarboxylase. (477 aa)
	PNMT	Phenylethanolamine N-methyltransferase. (144 aa)
	TYR	Tyrosinase. (541 aa)
	LOC106939669	Uncharacterized protein. (118 aa)
	LOC106948594	Fumarylacetoacetate hydrolase domain containing 2A. (321 aa)
	ENSPLAP00000019957	Uncharacterized protein. (212 aa)
	aox1	Aldehyde oxidase 6. (1304 aa)
	LOC106944044	D-dopachrome tautomerase. (118 aa)
	th	Tyrosine hydroxylase. (489 aa)
	LOC106944551	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (497 aa)
	FIGNL2	Fidgetin like 2. (694 aa)
	LOC106961688	S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (376 aa)
	ENSPLAP00000026564	Fumarylacetoacetate hydrolase domain containing 1. (218 aa)
	leng9	C3H1-type domain-containing protein. (568 aa)
	LOC106947057	4-hydroxyphenylpyruvate dioxygenase. (328 aa)
	LOC106935008	Amine oxidase. (511 aa)
	LOC106936608	Thioesterase superfamily member 6. (202 aa)
	LOC106941137	4-hydroxyphenylpyruvate dioxygenase. (334 aa)
	maob	Amine oxidase. (524 aa)
	LOC106947289	Amine oxidase. (540 aa)
	LOC106947294	Amine oxidase. (536 aa)
	ENSPLAP00000021639	Eosinophil peroxidase. (396 aa)
	adhfe1	Alcohol dehydrogenase iron containing 1. (433 aa)
	LOC106947407	Amine oxidase. (513 aa)
	GOT1	Aspartate aminotransferase. (410 aa)
	LOC106960764	Tyrosine hydroxylase 2. (465 aa)
	LOC106947437	Catechol-O-methyltransferase domain containing 1. (240 aa)
	LOC106935374	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (469 aa)
	hgd	Homogentisate 1,2-dioxygenase. (439 aa)
	LOC106956099	Tyrosinase related protein 1. (525 aa)
	LOC106934746	Tyrosinase-related protein 1b. (527 aa)

Your Current Organism:

Poecilia latipinna

NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPLAP00000006623	GOT1	ENSPLAP00000006623	ENSPLAP00000030858	Uncharacterized protein.	Aspartate aminotransferase.	0.904
ENSPLAP00000006623	LOC106939669	ENSPLAP00000006623	ENSPLAP00000019613	Uncharacterized protein.	Uncharacterized protein.	0.649
ENSPLAP00000006623	LOC106941137	ENSPLAP00000006623	ENSPLAP00000023118	Uncharacterized protein.	4-hydroxyphenylpyruvate dioxygenase.	0.903
ENSPLAP00000006623	LOC106941463	ENSPLAP00000006623	ENSPLAP00000015398	Uncharacterized protein.	Tyrosine aminotransferase.	0.910
ENSPLAP00000006623	LOC106944044	ENSPLAP00000006623	ENSPLAP00000020270	Uncharacterized protein.	D-dopachrome tautomerase.	0.649
ENSPLAP00000006623	LOC106947057	ENSPLAP00000006623	ENSPLAP00000025424	Uncharacterized protein.	4-hydroxyphenylpyruvate dioxygenase.	0.904
ENSPLAP00000006623	LOC106947407	ENSPLAP00000006623	ENSPLAP00000030970	Uncharacterized protein.	Amine oxidase.	0.535
ENSPLAP00000006623	got1	ENSPLAP00000006623	ENSPLAP00000005642	Uncharacterized protein.	Aspartate aminotransferase.	0.902
ENSPLAP00000006623	got2	ENSPLAP00000006623	ENSPLAP00000013232	Uncharacterized protein.	Aspartate aminotransferase.	0.906
ENSPLAP00000006623	hpdl	ENSPLAP00000006623	ENSPLAP00000004303	Uncharacterized protein.	4-hydroxyphenylpyruvate dioxygenase.	0.522
ENSPLAP00000006623	maob	ENSPLAP00000006623	ENSPLAP00000022005	Uncharacterized protein.	Amine oxidase.	0.500
ENSPLAP00000021639	GOT1	ENSPLAP00000021639	ENSPLAP00000030858	Eosinophil peroxidase.	Aspartate aminotransferase.	0.960
ENSPLAP00000021639	LOC106947407	ENSPLAP00000021639	ENSPLAP00000030970	Eosinophil peroxidase.	Amine oxidase.	0.480
ENSPLAP00000021639	LOC106960764	ENSPLAP00000021639	ENSPLAP00000030659	Eosinophil peroxidase.	Tyrosine hydroxylase 2.	0.960
ENSPLAP00000021639	TPO	ENSPLAP00000021639	ENSPLAP00000002979	Eosinophil peroxidase.	Thyroid peroxidase.	0.907
ENSPLAP00000021639	TYR	ENSPLAP00000021639	ENSPLAP00000019447	Eosinophil peroxidase.	Tyrosinase.	0.955
ENSPLAP00000021639	ddc	ENSPLAP00000021639	ENSPLAP00000027964	Eosinophil peroxidase.	Dopa decarboxylase.	0.913
ENSPLAP00000021639	got1	ENSPLAP00000021639	ENSPLAP00000005642	Eosinophil peroxidase.	Aspartate aminotransferase.	0.932
ENSPLAP00000021639	got2	ENSPLAP00000021639	ENSPLAP00000013232	Eosinophil peroxidase.	Aspartate aminotransferase.	0.959
ENSPLAP00000021639	maob	ENSPLAP00000021639	ENSPLAP00000022005	Eosinophil peroxidase.	Amine oxidase.	0.480