STRINGSTRING
jun jun shc1 shc1 KRAS KRAS LOC106962582 LOC106962582 akt1 akt1 LOC106952041 LOC106952041 LOC106947770 LOC106947770 nrg2 nrg2 LOC106940130 LOC106940130 tmeff2 tmeff2 LOC106964589 LOC106964589 ENSPLAP00000004498 ENSPLAP00000004498 LOC106934486 LOC106934486 crk crk areg areg abl2 abl2 ENSPLAP00000003357 ENSPLAP00000003357 abl1 abl1 ENSPLAP00000002892 ENSPLAP00000002892 ENSPLAP00000002780 ENSPLAP00000002780 LOC106934590 LOC106934590 plcg1 plcg1 hras hras gab1 gab1 LOC106964023 LOC106964023 ENSPLAP00000001643 ENSPLAP00000001643 camk2a camk2a ENSPLAP00000000459 ENSPLAP00000000459 CSDE1 CSDE1 cbl cbl ENSPLAP00000028832 ENSPLAP00000028832 LOC106952749 LOC106952749 erbb4 erbb4 araf araf LOC106956726 LOC106956726 PRKCA PRKCA pak1 pak1 nck2 nck2 LOC106936768 LOC106936768 LOC106959359 LOC106959359 LOC106946032 LOC106946032 LOC106956630 LOC106956630 LOC106955966 LOC106955966 ppp1r14b ppp1r14b LOC106964991 LOC106964991 LOC106938420 LOC106938420 pak4 pak4 LOC106957043 LOC106957043 alkbh4 alkbh4 LOC106946273 LOC106946273 LOC106951627 LOC106951627 sos2 sos2 ptk2 ptk2 map2k7 map2k7 ENSPLAP00000026113 ENSPLAP00000026113 PRKCB PRKCB ENSPLAP00000025924 ENSPLAP00000025924 mapk10 mapk10 LOC106936424 LOC106936424 LOC106945081 LOC106945081 ENSPLAP00000025078 ENSPLAP00000025078 LOC106952302 LOC106952302 LOC106940006 LOC106940006 tgfa tgfa gem gem ENSPLAP00000024103 ENSPLAP00000024103 map2k2 map2k2 LOC106947213 LOC106947213 rrad rrad plcg2 plcg2 PAK3 PAK3 shc2 shc2 braf braf ENSPLAP00000021720 ENSPLAP00000021720 ENSPLAP00000021704 ENSPLAP00000021704 pak2 pak2 ENSPLAP00000021432 ENSPLAP00000021432 LOC106952554 LOC106952554 LOC106937458 LOC106937458 LOC106953556 LOC106953556 ENSPLAP00000020617 ENSPLAP00000020617 pak5 pak5 LOC106937578 LOC106937578 LOC106962026 LOC106962026 ENSPLAP00000028607 ENSPLAP00000028607 ENSPLAP00000018907 ENSPLAP00000018907 LOC106954618 LOC106954618 ENSPLAP00000018535 ENSPLAP00000018535 LOC106943163 LOC106943163 LOC106958643 LOC106958643 LOC106940530 LOC106940530 REM1 REM1 LOC106938218 LOC106938218 egf egf ELK3 ELK3 LOC106955349 LOC106955349 gsk3b gsk3b LOC106941359 LOC106941359 LOC106957375 LOC106957375 LOC106940613 LOC106940613 mapk1 mapk1 erbb2 erbb2 egfr egfr pik3cd pik3cd LOC106944787 LOC106944787 raf1 raf1 LOC106957415 LOC106957415 LOC106941461 LOC106941461 LOC106936878 LOC106936878 pik3cb pik3cb LOC106961530 LOC106961530 SRC SRC LOC106943390 LOC106943390 LOC106949326 LOC106949326 SHC4 SHC4 camk2b camk2b EIF4EBP1 EIF4EBP1 LOC106963655 LOC106963655 pik3r3 pik3r3 LOC106940830 LOC106940830 LOC106935514 LOC106935514 ENSPLAP00000012518 ENSPLAP00000012518 LOC106935515 LOC106935515 erbb3 erbb3 akt3 akt3 grb2 grb2 LOC106962379 LOC106962379 LOC106942675 LOC106942675 rps6kb2 rps6kb2 ENSPLAP00000011191 ENSPLAP00000011191 map2k1 map2k1 nck1 nck1 ENSPLAP00000010414 ENSPLAP00000010414 LOC106954850 LOC106954850 LOC106941232 LOC106941232 LOC106941275 LOC106941275 LOC106939953 LOC106939953 bad bad ENSPLAP00000009487 ENSPLAP00000009487 LOC106954316 LOC106954316 LOC106961789 LOC106961789 LOC106954325 LOC106954325 ENSPLAP00000009115 ENSPLAP00000009115 ENSPLAP00000009083 ENSPLAP00000009083 ENSPLAP00000008567 ENSPLAP00000008567 SHC3 SHC3 LOC106943603 LOC106943603 LOC106949178 LOC106949178 LOC106941703 LOC106941703 LOC106954976 LOC106954976
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
junJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (288 aa)
shc1SHC (Src homology 2 domain containing) transforming protein 1. (576 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
LOC106962582Transcriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (430 aa)
akt1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (473 aa)
LOC106952041Neuregulin 2a. (595 aa)
LOC106947770Non-specific serine/threonine protein kinase. (507 aa)
nrg2Neuregulin 2b. (696 aa)
LOC106940130Uncharacterized protein. (627 aa)
tmeff2Transmembrane protein with EGF-like and two follistatin-like domains 2a. (354 aa)
LOC106964589Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (482 aa)
ENSPLAP00000004498Protein kinase domain-containing protein. (312 aa)
LOC106934486Receptor protein-tyrosine kinase. (1164 aa)
crkCRK proto-oncogene, adaptor protein. (306 aa)
aregAmphiregulin. (214 aa)
abl2Tyrosine-protein kinase. (1186 aa)
ENSPLAP00000003357CSD_1 domain-containing protein. (95 aa)
abl1Tyrosine-protein kinase. (1117 aa)
ENSPLAP00000002892Kazal-like domain-containing protein. (90 aa)
ENSPLAP00000002780Uncharacterized protein. (117 aa)
LOC106934590Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
plcg1Phosphoinositide phospholipase C. (1104 aa)
hrasHRas proto-oncogene, GTPase a. (189 aa)
gab1GRB2-associated binding protein 1. (687 aa)
LOC106964023Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (433 aa)
ENSPLAP00000001643Uncharacterized protein. (104 aa)
camk2aCalcium/calmodulin-dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (469 aa)
ENSPLAP00000000459Uncharacterized protein. (285 aa)
CSDE1Cold shock domain containing E1, RNA-binding. (675 aa)
cblCbl proto-oncogene, E3 ubiquitin protein ligase. (957 aa)
ENSPLAP00000028832CaMKII_AD domain-containing protein. (187 aa)
LOC106952749BHLH domain-containing protein. (382 aa)
erbb4Receptor protein-tyrosine kinase. (1174 aa)
arafA-Raf proto-oncogene, serine/threonine kinase. (604 aa)
LOC106956726JunE proto-oncogene, AP-1 transcription factor subunit. (323 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (671 aa)
pak1Non-specific serine/threonine protein kinase. (562 aa)
nck2Cytoplasmic protein. (393 aa)
LOC106936768Uncharacterized protein. (289 aa)
LOC106959359Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (459 aa)
LOC106946032Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1074 aa)
LOC106956630Receptor protein-tyrosine kinase. (1271 aa)
LOC106955966Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (474 aa)
ppp1r14bProtein phosphatase 1, regulatory (inhibitor) subunit 14Bb. (132 aa)
LOC106964991Mitogen-activated protein kinase kinase 4b; Belongs to the protein kinase superfamily. (418 aa)
LOC106938420Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (694 aa)
pak4Non-specific serine/threonine protein kinase. (646 aa)
LOC106957043Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (680 aa)
alkbh4AlkB homolog 4, lysine demthylase. (279 aa)
LOC106946273Uncharacterized protein. (858 aa)
LOC106951627Zgc:55558. (187 aa)
sos2Son of sevenless homolog 2 (Drosophila). (1324 aa)
ptk2Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1125 aa)
map2k7Mitogen-activated protein kinase kinase 7. (439 aa)
ENSPLAP00000026113AGC-kinase C-terminal domain-containing protein. (55 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (680 aa)
ENSPLAP00000025924Protein kinase domain-containing protein. (144 aa)
mapk10Mitogen-activated protein kinase. (360 aa)
LOC106936424STAT_int domain-containing protein. (391 aa)
LOC106945081Transcriptional regulator Myc-like. (430 aa)
ENSPLAP00000025078FERM domain-containing protein. (281 aa)
LOC106952302Non-specific serine/threonine protein kinase. (696 aa)
LOC106940006GRB2 related adaptor protein 2a. (285 aa)
tgfaTransforming growth factor, alpha. (247 aa)
gemGTP binding protein overexpressed in skeletal muscle. (292 aa)
ENSPLAP00000024103Kazal-like domain-containing protein. (83 aa)
map2k2Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily. (399 aa)
LOC106947213Phosphoinositide-3-kinase, regulatory subunit 1 (alpha). (727 aa)
rradRas-related associated with diabetes. (309 aa)
plcg2Phosphoinositide phospholipase C. (1091 aa)
PAK3Non-specific serine/threonine protein kinase. (550 aa)
shc2SHC (Src homology 2 domain containing) transforming protein 2. (549 aa)
brafB-Raf proto-oncogene, serine/threonine kinase. (753 aa)
ENSPLAP00000021720Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (252 aa)
ENSPLAP00000021704Zgc:158659; Belongs to the PI3/PI4-kinase family. (503 aa)
pak2Non-specific serine/threonine protein kinase. (525 aa)
ENSPLAP00000021432EGF-like domain-containing protein. (134 aa)
LOC106952554Eukaryotic translation initiation factor 4E binding protein 1. (121 aa)
LOC106937458Cyclin-dependent kinase inhibitor 1-like. (156 aa)
LOC106953556Cyclin-dependent kinase inhibitor 1Bb. (194 aa)
ENSPLAP00000020617SH2 domain-containing protein. (231 aa)
pak5Non-specific serine/threonine protein kinase. (742 aa)
LOC1069375781-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1256 aa)
LOC106962026EGF-like domain-containing protein. (178 aa)
ENSPLAP00000028607PH domain-containing protein. (432 aa)
ENSPLAP00000018907EGF-like domain-containing protein. (599 aa)
LOC106954618Tyrosine-protein kinase. (527 aa)
ENSPLAP00000018535EGF-like domain-containing protein. (348 aa)
LOC106943163Uncharacterized protein. (441 aa)
LOC106958643Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (446 aa)
LOC106940530Myelocytomatosis oncogene homolog. (348 aa)
REM1RRAD and GEM like GTPase 1. (288 aa)
LOC106938218SH2 domain-containing protein. (384 aa)
egfEpidermal growth factor. (942 aa)
ELK3ETS transcription factor ELK3. (400 aa)
LOC106955349Erb-b2 receptor tyrosine kinase 3b. (1213 aa)
gsk3bGlycogen synthase kinase 3 beta, genome duplicate a; Belongs to the protein kinase superfamily. (421 aa)
LOC106941359Mechanistic target of rapamycin kinase. (927 aa)
LOC106957375Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
LOC106940613EGF-like domain-containing protein. (193 aa)
mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (364 aa)
erbb2Receptor protein-tyrosine kinase. (1019 aa)
egfrReceptor protein-tyrosine kinase. (1163 aa)
pik3cdPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1041 aa)
LOC106944787Mitogen-activated protein kinase. (460 aa)
raf1Raf-1 proto-oncogene, serine/threonine kinase a. (635 aa)
LOC106957415Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (515 aa)
LOC106941461Phosphoinositide-3-kinase, regulatory subunit 2 (beta). (434 aa)
LOC106936878ETS domain-containing protein. (376 aa)
pik3cbPhosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1079 aa)
LOC106961530Non-specific serine/threonine protein kinase. (662 aa)
SRCTyrosine-protein kinase. (550 aa)
LOC106943390Crk-like protein. (256 aa)
LOC106949326Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (509 aa)
SHC4SHC adaptor protein 4. (500 aa)
camk2bCalcium/calmodulin-dependent protein kinase (CaM kinase) II beta 2. (510 aa)
EIF4EBP1Eukaryotic translation initiation factor 4E binding protein 1. (119 aa)
LOC106963655Signal transducer and activator of transcription. (787 aa)
pik3r3Uncharacterized protein. (515 aa)
LOC106940830Protein kinase domain-containing protein. (181 aa)
LOC106935514Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (480 aa)
ENSPLAP00000012518CaMKII_AD domain-containing protein. (171 aa)
LOC106935515Ribosomal protein S6 kinase b, polypeptide 1b. (140 aa)
erbb3Protein kinase domain-containing protein. (1424 aa)
akt3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
grb2Growth factor receptor-bound protein 2b. (217 aa)
LOC106962379Mitogen-activated protein kinase 8b. (402 aa)
LOC106942675Uncharacterized protein. (439 aa)
rps6kb2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (470 aa)
ENSPLAP00000011191Phorbol-ester/DAG-type domain-containing protein. (55 aa)
map2k1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (394 aa)
nck1Cytoplasmic protein. (394 aa)
ENSPLAP00000010414Focal_AT domain-containing protein. (115 aa)
LOC106954850Cyclin-dependent kinase inhibitor 1A. (156 aa)
LOC106941232Uncharacterized protein. (174 aa)
LOC106941275Cyclin-dependent kinase inhibitor 1D. (179 aa)
LOC106939953Protein kinase C, beta a; Belongs to the protein kinase superfamily. (428 aa)
badBCL2 associated agonist of cell death b. (166 aa)
ENSPLAP00000009487AGC-kinase C-terminal domain-containing protein. (59 aa)
LOC106954316Uncharacterized protein. (465 aa)
LOC106961789Heparin-binding EGF-like growth factor a. (236 aa)
LOC106954325BZIP domain-containing protein; Belongs to the bZIP family. (323 aa)
ENSPLAP00000009115Protein kinase domain-containing protein. (158 aa)
ENSPLAP00000009083FERM_N_2 domain-containing protein. (74 aa)
ENSPLAP00000008567Son of sevenless homolog 1 (Drosophila). (436 aa)
SHC3SHC adaptor protein 3. (690 aa)
LOC106943603Crk-like protein. (256 aa)
LOC106949178Phosphoinositide phospholipase C. (531 aa)
LOC106941703V-crk avian sarcoma virus CT10 oncogene homolog-like. (256 aa)
LOC106954976Mitogen-activated protein kinase. (420 aa)
Your Current Organism:
Poecilia latipinna
NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly
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