STRINGSTRING
ENSPLAP00000012518 ENSPLAP00000012518 grb2 grb2 LOC106962379 LOC106962379 LOC106942675 LOC106942675 LOC106964344 LOC106964344 MAP2K6 MAP2K6 ENSPLAP00000011191 ENSPLAP00000011191 map2k1 map2k1 ENSPLAP00000011040 ENSPLAP00000011040 ENSPLAP00000010842 ENSPLAP00000010842 LOC106960475 LOC106960475 LOC106947790 LOC106947790 ADCY9 ADCY9 LOC106951757 LOC106951757 ENSPLAP00000006646 ENSPLAP00000006646 gnas gnas KRAS KRAS CACNA1D CACNA1D ENSPLAP00000007241 ENSPLAP00000007241 jun jun LOC106954976 LOC106954976 LOC106943627 LOC106943627 map3k3 map3k3 ENSPLAP00000008567 ENSPLAP00000008567 LOC106954325 LOC106954325 LOC106961789 LOC106961789 ENSPLAP00000009487 ENSPLAP00000009487 LOC106939953 LOC106939953 LOC106947659 LOC106947659 LOC106952231 LOC106952231 LOC106956919 LOC106956919 ENSPLAP00000010010 ENSPLAP00000010010 gnrh1 gnrh1 LOC106940873 LOC106940873 map2k7 map2k7 sos2 sos2 LOC106951627 LOC106951627 LOC106936350 LOC106936350 LOC106957043 LOC106957043 itpr2 itpr2 cga cga ENSPLAP00000027251 ENSPLAP00000027251 LOC106964991 LOC106964991 CSDE1 CSDE1 LOC106943350 LOC106943350 ENSPLAP00000028832 ENSPLAP00000028832 LOC106955448 LOC106955448 LOC106940730 LOC106940730 calm2 calm2 cacna1s cacna1s ENSPLAP00000029641 ENSPLAP00000029641 prkacb prkacb LOC106940130 LOC106940130 prkcd prkcd LOC106947839 LOC106947839 ENSPLAP00000004498 ENSPLAP00000004498 LOC106934486 LOC106934486 map3k4 map3k4 LOC106943542 LOC106943542 egr1 egr1 LOC106945205 LOC106945205 ENSPLAP00000003775 ENSPLAP00000003775 ENSPLAP00000003761 ENSPLAP00000003761 mmp2 mmp2 adcy6 adcy6 ENSPLAP00000003357 ENSPLAP00000003357 LOC106963247 LOC106963247 LOC106954508 LOC106954508 ENSPLAP00000002780 ENSPLAP00000002780 jmjd7 jmjd7 LOC106951125 LOC106951125 LOC106939558 LOC106939558 LOC106936789 LOC106936789 PLCB4 PLCB4 hras hras LOC106964023 LOC106964023 LOC106945964 LOC106945964 camk2a camk2a CDC42 CDC42 LOC106935811 LOC106935811 adcy1 adcy1 LOC106955270 LOC106955270 LOC106955875 LOC106955875 LOC106956726 LOC106956726 PRKCA PRKCA pla2g4a pla2g4a LOC106944750 LOC106944750 pld2 pld2 LOC106959359 LOC106959359 LOC106957331 LOC106957331 pla2g4c pla2g4c ENSPLAP00000031178 ENSPLAP00000031178 LOC106955966 LOC106955966 LOC106936878 LOC106936878 LOC106941471 LOC106941471 LOC106963571 LOC106963571 LOC106949502 LOC106949502 LOC106957415 LOC106957415 LOC106936200 LOC106936200 raf1 raf1 LOC106944787 LOC106944787 LOC106934683 LOC106934683 egfr egfr mapk1 mapk1 LOC106942295 LOC106942295 ENSPLAP00000017227 ENSPLAP00000017227 ELK3 ELK3 ENSPLAP00000017632 ENSPLAP00000017632 REM1 REM1 LOC106954010 LOC106954010 LOC106958643 LOC106958643 ENSPLAP00000018363 ENSPLAP00000018363 LOC106962062 LOC106962062 LOC106954618 LOC106954618 ENSPLAP00000018924 ENSPLAP00000018924 prkaca prkaca LOC106955889 LOC106955889 itpr1 itpr1 LOC106953777 LOC106953777 LOC106938139 LOC106938139 LOC106938138 LOC106938138 LOC106959955 LOC106959955 ENSPLAP00000019719 ENSPLAP00000019719 LOC106946593 LOC106946593 LOC106951123 LOC106951123 LOC106954512 LOC106954512 PLCB1 PLCB1 LOC106964683 LOC106964683 LOC106955117 LOC106955117 LOC106940189 LOC106940189 LOC106964606 LOC106964606 adcy2 adcy2 ENSPLAP00000023174 ENSPLAP00000023174 rrad rrad map2k2 map2k2 LOC106947704 LOC106947704 gem gem LOC106940006 LOC106940006 LOC106948891 LOC106948891 PLCB2 PLCB2 gnrh2 gnrh2 ADCY8 ADCY8 LOC106957719 LOC106957719 adcy3 adcy3 PTX3 PTX3 mapk7 mapk7 LOC106965147 LOC106965147 ENSPLAP00000025814 ENSPLAP00000025814 mapk10 mapk10 pld1 pld1 PRKCB PRKCB ENSPLAP00000026113 ENSPLAP00000026113 LOC106938306 LOC106938306 SRC SRC LOC106934757 LOC106934757 ENSPLAP00000014457 ENSPLAP00000014457 LOC106949352 LOC106949352 camk2b camk2b LOC106936277 LOC106936277 LOC106965019 LOC106965019
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSPLAP00000012518CaMKII_AD domain-containing protein. (171 aa)
grb2Growth factor receptor-bound protein 2b. (217 aa)
LOC106962379Mitogen-activated protein kinase 8b. (402 aa)
LOC106942675Uncharacterized protein. (439 aa)
LOC106964344G_PROTEIN_RECEP_F1_2 domain-containing protein. (406 aa)
MAP2K6Mitogen-activated protein kinase kinase 6. (336 aa)
ENSPLAP00000011191Phorbol-ester/DAG-type domain-containing protein. (55 aa)
map2k1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (394 aa)
ENSPLAP00000011040MIR domain-containing protein. (227 aa)
ENSPLAP00000010842Calmodulin-like 4a. (117 aa)
LOC106960475Mitogen-activated protein kinase. (357 aa)
LOC106947790Guanine nucleotide binding protein (G protein), alpha 11b (Gq class). (359 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1431 aa)
LOC106951757Mitogen-activated protein kinase kinase 6. (380 aa)
ENSPLAP00000006646Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (314 aa)
gnasUncharacterized protein. (391 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1583 aa)
ENSPLAP00000007241Calcium channel, voltage-dependent, L type, alpha 1D subunit, b. (87 aa)
junJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (288 aa)
LOC106954976Mitogen-activated protein kinase. (420 aa)
LOC106943627Mitogen-activated protein kinase. (272 aa)
map3k3Mitogen-activated protein kinase kinase kinase 3. (617 aa)
ENSPLAP00000008567Son of sevenless homolog 1 (Drosophila). (436 aa)
LOC106954325BZIP domain-containing protein; Belongs to the bZIP family. (323 aa)
LOC106961789Heparin-binding EGF-like growth factor a. (236 aa)
ENSPLAP00000009487AGC-kinase C-terminal domain-containing protein. (59 aa)
LOC106939953Protein kinase C, beta a; Belongs to the protein kinase superfamily. (428 aa)
LOC106947659Mitogen-activated protein kinase. (364 aa)
LOC106952231Uncharacterized protein. (191 aa)
LOC106956919Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (827 aa)
ENSPLAP00000010010MIR domain-containing protein. (213 aa)
gnrh1Uncharacterized protein. (94 aa)
LOC106940873Luteinizing hormone, beta polypeptide. (160 aa)
map2k7Mitogen-activated protein kinase kinase 7. (439 aa)
sos2Son of sevenless homolog 2 (Drosophila). (1324 aa)
LOC106951627Zgc:55558. (187 aa)
LOC106936350Inositol 1,4,5-trisphosphate receptor, type 1b. (2662 aa)
LOC106957043Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (680 aa)
itpr2Inositol 1,4,5-trisphosphate receptor, type 2. (2635 aa)
cgaGlycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. (134 aa)
ENSPLAP00000027251Uncharacterized protein. (375 aa)
LOC106964991Mitogen-activated protein kinase kinase 4b; Belongs to the protein kinase superfamily. (418 aa)
CSDE1Cold shock domain containing E1, RNA-binding. (675 aa)
LOC106943350Mitogen-activated protein kinase 12-like. (272 aa)
ENSPLAP00000028832CaMKII_AD domain-containing protein. (187 aa)
LOC106955448Protein kinase, cAMP-dependent, catalytic, beta b; Belongs to the protein kinase superfamily. (351 aa)
LOC106940730G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (455 aa)
calm2Calmodulin 2. (149 aa)
cacna1sVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1356 aa)
ENSPLAP00000029641Ion_trans domain-containing protein. (192 aa)
prkacbUncharacterized protein. (300 aa)
LOC106940130Uncharacterized protein. (627 aa)
prkcdProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (683 aa)
LOC106947839Mitogen-activated protein kinase. (363 aa)
ENSPLAP00000004498Protein kinase domain-containing protein. (312 aa)
LOC106934486Receptor protein-tyrosine kinase. (1164 aa)
map3k4Mitogen-activated protein kinase kinase kinase 4. (1570 aa)
LOC106943542Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (909 aa)
egr1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (512 aa)
LOC106945205Calcium channel, voltage-dependent, L type, alpha 1D subunit, a. (1954 aa)
ENSPLAP00000003775Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1160 aa)
ENSPLAP00000003761Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (330 aa)
mmp2Matrix metallopeptidase 2. (657 aa)
adcy6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1181 aa)
ENSPLAP00000003357CSD_1 domain-containing protein. (95 aa)
LOC106963247Calmodulin 2a (phosphorylase kinase, delta); Belongs to the calmodulin family. (149 aa)
LOC106954508G protein subunit alpha q. (359 aa)
ENSPLAP00000002780Uncharacterized protein. (117 aa)
jmjd7Jumonji domain containing 7. (312 aa)
LOC106951125Uncharacterized protein. (191 aa)
LOC106939558Uncharacterized protein. (760 aa)
LOC106936789Activating transcription factor 4a. (424 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1111 aa)
hrasHRas proto-oncogene, GTPase a. (189 aa)
LOC106964023Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (433 aa)
LOC106945964Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1447 aa)
camk2aCalcium/calmodulin-dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (469 aa)
CDC42Cell division cycle 42. (191 aa)
LOC106935811Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2926 aa)
adcy1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1058 aa)
LOC106955270Guanine nucleotide binding protein (G protein), alpha 11a (Gq class). (359 aa)
LOC106955875Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1188 aa)
LOC106956726JunE proto-oncogene, AP-1 transcription factor subunit. (323 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (671 aa)
pla2g4aPhospholipase A2. (717 aa)
LOC106944750Matrix metallopeptidase 14a (membrane-inserted). (557 aa)
pld2Phospholipase. (954 aa)
LOC106959359Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (459 aa)
LOC106957331Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1054 aa)
pla2g4cPLA2c domain-containing protein. (462 aa)
ENSPLAP00000031178Uncharacterized protein. (271 aa)
LOC106955966Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (474 aa)
LOC106936878ETS domain-containing protein. (376 aa)
LOC106941471Uncharacterized protein; Belongs to the protein kinase superfamily. (351 aa)
LOC106963571Uncharacterized protein. (359 aa)
LOC106949502Mitogen-activated protein kinase kinase kinase 2. (633 aa)
LOC106957415Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (515 aa)
LOC106936200Calmodulin. (149 aa)
raf1Raf-1 proto-oncogene, serine/threonine kinase a. (635 aa)
LOC106944787Mitogen-activated protein kinase. (460 aa)
LOC106934683Protein tyrosine kinase 2 beta, b; Belongs to the protein kinase superfamily. Tyr protein kinase family. (995 aa)
egfrReceptor protein-tyrosine kinase. (1163 aa)
mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (364 aa)
LOC106942295Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1147 aa)
ENSPLAP00000017227Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (299 aa)
ELK3ETS transcription factor ELK3. (400 aa)
ENSPLAP00000017632Ca_chan_IQ domain-containing protein. (326 aa)
REM1RRAD and GEM like GTPase 1. (288 aa)
LOC106954010Calmodulin. (149 aa)
LOC106958643Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (446 aa)
ENSPLAP00000018363Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (640 aa)
LOC106962062G_PROTEIN_RECEP_F1_2 domain-containing protein. (401 aa)
LOC106954618Tyrosine-protein kinase. (527 aa)
ENSPLAP00000018924Phosphoinositide phospholipase C. (1018 aa)
prkacaProtein kinase, cAMP-dependent, catalytic, alpha, genome duplicate b; Belongs to the protein kinase superfamily. (333 aa)
LOC106955889Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (361 aa)
itpr1Inositol 1,4,5-trisphosphate receptor, type 1a. (2699 aa)
LOC106953777G_PROTEIN_RECEP_F1_2 domain-containing protein. (422 aa)
LOC106938139Mitogen-activated protein kinase. (357 aa)
LOC106938138Protein kinase domain-containing protein. (104 aa)
LOC106959955Phosphoinositide phospholipase C. (1062 aa)
ENSPLAP00000019719Uncharacterized protein. (90 aa)
LOC106946593Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily. (351 aa)
LOC106951123Uncharacterized protein. (191 aa)
LOC106954512Guanine nucleotide binding protein (G protein), alpha 14. (351 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1244 aa)
LOC106964683Cell division cycle 42. (191 aa)
LOC106955117Mitogen-activated protein kinase. (360 aa)
LOC106940189Uncharacterized protein. (77 aa)
LOC106964606Activating transcription factor 4b. (434 aa)
adcy2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1057 aa)
ENSPLAP00000023174Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (240 aa)
rradRas-related associated with diabetes. (309 aa)
map2k2Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily. (399 aa)
LOC106947704Gonadoliberin; Stimulates the secretion of gonadotropins. Belongs to the GnRH family. (91 aa)
gemGTP binding protein overexpressed in skeletal muscle. (292 aa)
LOC106940006GRB2 related adaptor protein 2a. (285 aa)
LOC106948891Mitogen-activated protein kinase kinase kinase 22. (618 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1275 aa)
gnrh2Gonadoliberin; Stimulates the secretion of gonadotropins. Belongs to the GnRH family. (94 aa)
ADCY8Adenylate cyclase 8; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (528 aa)
LOC106957719Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1071 aa)
adcy3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1113 aa)
PTX3Pentraxin 3, long a. (448 aa)
mapk7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (1071 aa)
LOC106965147GNAS complex locus. (379 aa)
ENSPLAP00000025814Ion_trans domain-containing protein. (479 aa)
mapk10Mitogen-activated protein kinase. (360 aa)
pld1Phospholipase. (1059 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (680 aa)
ENSPLAP00000026113AGC-kinase C-terminal domain-containing protein. (55 aa)
LOC106938306Cys_knot domain-containing protein. (130 aa)
SRCTyrosine-protein kinase. (550 aa)
LOC106934757Matrix metallopeptidase 14b (membrane-inserted). (616 aa)
ENSPLAP00000014457AGC-kinase C-terminal domain-containing protein. (80 aa)
LOC106949352Adenylate cyclase 2a; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (847 aa)
camk2bCalcium/calmodulin-dependent protein kinase (CaM kinase) II beta 2. (510 aa)
LOC106936277Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1196 aa)
LOC106965019Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (686 aa)
Your Current Organism:
Poecilia latipinna
NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly
Server load: low (10%) [HD]