(17 nodes) Peptidase M10A, cysteine switch, zinc binding site, and Tissue inhibitor of metalloproteinase, conserved site network (Poecilia mexicana)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSPMEP00000000475	ZnMc domain-containing protein. (406 aa)
	mmp15	Matrix metallopeptidase 15b. (656 aa)
	LOC106926970	Matrix metallopeptidase 14b (membrane-inserted). (618 aa)
	timp2	TIMP metallopeptidase inhibitor 2a. (221 aa)
	LOC106926288	ZnMc domain-containing protein. (325 aa)
	mmp2	Matrix metallopeptidase 2. (657 aa)
	LOC106920080	TIMP metallopeptidase inhibitor 2b. (220 aa)
	LOC106908664	Matrix metallopeptidase 25b. (569 aa)
	MMP1	Matrix metallopeptidase 1. (461 aa)
	LOC106906145	Matrix metallopeptidase 20a (enamelysin). (465 aa)
	LOC106909070	ZnMc domain-containing protein. (425 aa)
	ENSPMEP00000026435	ZnMc domain-containing protein. (141 aa)
	LOC106926286	Matrix metallopeptidase 30. (473 aa)
	scube2	Signal peptide, CUB domain, EGF-like 2. (928 aa)
	mmp14	Matrix metallopeptidase 14a (membrane-inserted). (557 aa)
	LOC106913043	Uncharacterized protein. (693 aa)
	mmp16	Matrix metallopeptidase 16b (membrane-inserted). (612 aa)

Your Current Organism:

Poecilia mexicana

NCBI taxonomy Id: 48701
Other names: shortfin molly

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPMEP00000000475	LOC106906145	ENSPMEP00000000475	ENSPMEP00000021017	ZnMc domain-containing protein.	Matrix metallopeptidase 20a (enamelysin).	0.501
ENSPMEP00000000475	LOC106920080	ENSPMEP00000000475	ENSPMEP00000013151	ZnMc domain-containing protein.	TIMP metallopeptidase inhibitor 2b.	0.728
ENSPMEP00000000475	LOC106926286	ENSPMEP00000000475	ENSPMEP00000026644	ZnMc domain-containing protein.	Matrix metallopeptidase 30.	0.497
ENSPMEP00000000475	LOC106926288	ENSPMEP00000000475	ENSPMEP00000008540	ZnMc domain-containing protein.	ZnMc domain-containing protein.	0.520
ENSPMEP00000000475	MMP1	ENSPMEP00000000475	ENSPMEP00000017908	ZnMc domain-containing protein.	Matrix metallopeptidase 1.	0.511
ENSPMEP00000000475	mmp2	ENSPMEP00000000475	ENSPMEP00000010920	ZnMc domain-containing protein.	Matrix metallopeptidase 2.	0.467
ENSPMEP00000000475	scube2	ENSPMEP00000000475	ENSPMEP00000027377	ZnMc domain-containing protein.	Signal peptide, CUB domain, EGF-like 2.	0.495
ENSPMEP00000000475	timp2	ENSPMEP00000000475	ENSPMEP00000007354	ZnMc domain-containing protein.	TIMP metallopeptidase inhibitor 2a.	0.728
ENSPMEP00000026435	LOC106906145	ENSPMEP00000026435	ENSPMEP00000021017	ZnMc domain-containing protein.	Matrix metallopeptidase 20a (enamelysin).	0.478
ENSPMEP00000026435	LOC106909070	ENSPMEP00000026435	ENSPMEP00000021469	ZnMc domain-containing protein.	ZnMc domain-containing protein.	0.613
ENSPMEP00000026435	LOC106920080	ENSPMEP00000026435	ENSPMEP00000013151	ZnMc domain-containing protein.	TIMP metallopeptidase inhibitor 2b.	0.701
ENSPMEP00000026435	LOC106926286	ENSPMEP00000026435	ENSPMEP00000026644	ZnMc domain-containing protein.	Matrix metallopeptidase 30.	0.479
ENSPMEP00000026435	LOC106926288	ENSPMEP00000026435	ENSPMEP00000008540	ZnMc domain-containing protein.	ZnMc domain-containing protein.	0.511
ENSPMEP00000026435	LOC106926970	ENSPMEP00000026435	ENSPMEP00000004944	ZnMc domain-containing protein.	Matrix metallopeptidase 14b (membrane-inserted).	0.488
ENSPMEP00000026435	MMP1	ENSPMEP00000026435	ENSPMEP00000017908	ZnMc domain-containing protein.	Matrix metallopeptidase 1.	0.482
ENSPMEP00000026435	mmp15	ENSPMEP00000026435	ENSPMEP00000003557	ZnMc domain-containing protein.	Matrix metallopeptidase 15b.	0.485
ENSPMEP00000026435	mmp2	ENSPMEP00000026435	ENSPMEP00000010920	ZnMc domain-containing protein.	Matrix metallopeptidase 2.	0.465
ENSPMEP00000026435	timp2	ENSPMEP00000026435	ENSPMEP00000007354	ZnMc domain-containing protein.	TIMP metallopeptidase inhibitor 2a.	0.701
LOC106906145	ENSPMEP00000000475	ENSPMEP00000021017	ENSPMEP00000000475	Matrix metallopeptidase 20a (enamelysin).	ZnMc domain-containing protein.	0.501
LOC106906145	ENSPMEP00000026435	ENSPMEP00000021017	ENSPMEP00000026435	Matrix metallopeptidase 20a (enamelysin).	ZnMc domain-containing protein.	0.478