(16 nodes) Regulation of FZD by ubiquitination, and Cytoplasm protein quality control network (Poecilia mexicana)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	rnf43	Ring finger protein 43. (847 aa)
	rnf215	Ring finger protein 215. (365 aa)
	RSPO3	Uncharacterized protein. (329 aa)
	LOC106918175	Si:ch211-81a5.1. (258 aa)
	znrf3	Zinc and ring finger 3. (855 aa)
	LGR6	Leucine rich repeat containing G protein-coupled receptor 6. (938 aa)
	LOC106911841	R-spondin-3-like. (329 aa)
	LOC106909988	G_PROTEIN_RECEP_F1_2 domain-containing protein. (931 aa)
	LGR5	Leucine rich repeat containing G protein-coupled receptor 5. (926 aa)
	rspo2	R-spondin 2. (245 aa)
	RSPO3-2	Uncharacterized protein. (176 aa)
	LOC106909673	Leucine-rich repeat containing G protein-coupled receptor 4. (988 aa)
	rnf126	RING-type domain-containing protein. (325 aa)
	lrtm1	Leucine rich repeats and transmembrane domains 1. (377 aa)
	ENSPMEP00000032484	R-spondin 3. (313 aa)
	LOC106910773	R-spondin 4. (341 aa)

Your Current Organism:

Poecilia mexicana

NCBI taxonomy Id: 48701
Other names: shortfin molly

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPMEP00000032484	LGR5	ENSPMEP00000032484	ENSPMEP00000019706	R-spondin 3.	Leucine rich repeat containing G protein-coupled receptor 5.	0.921
ENSPMEP00000032484	LGR6	ENSPMEP00000032484	ENSPMEP00000014723	R-spondin 3.	Leucine rich repeat containing G protein-coupled receptor 6.	0.919
ENSPMEP00000032484	LOC106909673	ENSPMEP00000032484	ENSPMEP00000025350	R-spondin 3.	Leucine-rich repeat containing G protein-coupled receptor 4.	0.898
ENSPMEP00000032484	LOC106909988	ENSPMEP00000032484	ENSPMEP00000018980	R-spondin 3.	G_PROTEIN_RECEP_F1_2 domain-containing protein.	0.898
ENSPMEP00000032484	LOC106910773	ENSPMEP00000032484	ENSPMEP00000034146	R-spondin 3.	R-spondin 4.	0.808
ENSPMEP00000032484	LOC106918175	ENSPMEP00000032484	ENSPMEP00000011738	R-spondin 3.	Si:ch211-81a5.1.	0.651
ENSPMEP00000032484	lrtm1	ENSPMEP00000032484	ENSPMEP00000029690	R-spondin 3.	Leucine rich repeats and transmembrane domains 1.	0.609
ENSPMEP00000032484	rnf126	ENSPMEP00000032484	ENSPMEP00000025809	R-spondin 3.	RING-type domain-containing protein.	0.651
ENSPMEP00000032484	rnf215	ENSPMEP00000032484	ENSPMEP00000010369	R-spondin 3.	Ring finger protein 215.	0.651
ENSPMEP00000032484	rnf43	ENSPMEP00000032484	ENSPMEP00000009979	R-spondin 3.	Ring finger protein 43.	0.934
ENSPMEP00000032484	rspo2	ENSPMEP00000032484	ENSPMEP00000023604	R-spondin 3.	R-spondin 2.	0.803
ENSPMEP00000032484	znrf3	ENSPMEP00000032484	ENSPMEP00000014264	R-spondin 3.	Zinc and ring finger 3.	0.942
LGR5	ENSPMEP00000032484	ENSPMEP00000019706	ENSPMEP00000032484	Leucine rich repeat containing G protein-coupled receptor 5.	R-spondin 3.	0.921
LGR5	LGR6	ENSPMEP00000019706	ENSPMEP00000014723	Leucine rich repeat containing G protein-coupled receptor 5.	Leucine rich repeat containing G protein-coupled receptor 6.	0.912
LGR5	LOC106909673	ENSPMEP00000019706	ENSPMEP00000025350	Leucine rich repeat containing G protein-coupled receptor 5.	Leucine-rich repeat containing G protein-coupled receptor 4.	0.913
LGR5	LOC106909988	ENSPMEP00000019706	ENSPMEP00000018980	Leucine rich repeat containing G protein-coupled receptor 5.	G_PROTEIN_RECEP_F1_2 domain-containing protein.	0.913
LGR5	LOC106910773	ENSPMEP00000019706	ENSPMEP00000034146	Leucine rich repeat containing G protein-coupled receptor 5.	R-spondin 4.	0.941
LGR5	LOC106911841	ENSPMEP00000019706	ENSPMEP00000016451	Leucine rich repeat containing G protein-coupled receptor 5.	R-spondin-3-like.	0.921
LGR5	LOC106918175	ENSPMEP00000019706	ENSPMEP00000011738	Leucine rich repeat containing G protein-coupled receptor 5.	Si:ch211-81a5.1.	0.656
LGR5	RSPO3	ENSPMEP00000019706	ENSPMEP00000010538	Leucine rich repeat containing G protein-coupled receptor 5.	Uncharacterized protein.	0.921