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txnrd2 txnrd2 pdha1 pdha1 dlat dlat SDHB SDHB LOC106919110 LOC106919110 LOC106919109 LOC106919109 ENSPMEP00000001758 ENSPMEP00000001758 ogdh ogdh GOT1 GOT1 suclg1 suclg1 LOC106928075 LOC106928075 nit2 nit2 got2 got2 dhtkd1 dhtkd1 LOC106925048 LOC106925048 LOC106913728 LOC106913728 bckdha bckdha LOC106919662 LOC106919662 LOC106904366 LOC106904366 LOC106930075 LOC106930075 idh3g idh3g dld dld idh1 idh1 sdha sdha ENSPMEP00000010547 ENSPMEP00000010547 suclg2 suclg2 sdhc sdhc idh3a idh3a idh2 idh2 bckdhb bckdhb sucla2 sucla2 idh3b idh3b LOC106920007 LOC106920007 MDH2 MDH2 OGDH OGDH LOC106903454 LOC106903454 ENSPMEP00000018203 ENSPMEP00000018203 LOC106905448 LOC106905448 LOC106928397 LOC106928397 got1 got1 sdhd sdhd gpt gpt LOC106903771 LOC106903771 ACLY ACLY aco1 aco1 IDH2 IDH2 mdh1 mdh1 ddo ddo ACO2 ACO2 pdhx pdhx pdhb pdhb agxt2 agxt2 LOC106924537 LOC106924537 LOC106930998 LOC106930998 dbt dbt cs cs
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
txnrd2Thioredoxin reductase 2, tandem duplicate 1. (512 aa)
pdha1Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (390 aa)
dlatAcetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (643 aa)
SDHBSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (283 aa)
LOC106919110Aminotran_1_2 domain-containing protein. (473 aa)
LOC106919109Aminotran_1_2 domain-containing protein. (472 aa)
ENSPMEP00000001758Aminotran_1_2 domain-containing protein. (179 aa)
ogdhOxoglutarate (alpha-ketoglutarate) dehydrogenase b (lipoamide). (1039 aa)
GOT1Aspartate aminotransferase. (410 aa)
suclg1Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. (329 aa)
LOC106928075Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (279 aa)
nit2Nitrilase family, member 2. (286 aa)
got2Aspartate aminotransferase. (428 aa)
dhtkd1Dehydrogenase E1 and transketolase domain containing 1. (946 aa)
LOC106925048Serine--pyruvate aminotransferase. (394 aa)
LOC106913728Malate dehydrogenase. (333 aa)
bckdha2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (447 aa)
LOC106919662Lipoyl-binding domain-containing protein. (170 aa)
LOC106904366Glutamate dehydrogenase 1b; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (542 aa)
LOC106930075Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (782 aa)
idh3gIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (392 aa)
dldDihydrolipoyl dehydrogenase. (483 aa)
idh1Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (414 aa)
sdhaSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (663 aa)
ENSPMEP00000010547Malate dehydrogenase. (230 aa)
suclg2Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (431 aa)
sdhcSuccinate dehydrogenase complex, subunit C, integral membrane protein. (169 aa)
idh3aIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (384 aa)
idh2Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (452 aa)
bckdhbBranched chain keto acid dehydrogenase E1 subunit beta. (387 aa)
sucla2Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (478 aa)
idh3bIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (386 aa)
LOC106920007Uncharacterized protein. (419 aa)
MDH2Malate dehydrogenase. (361 aa)
OGDHOxoglutarate dehydrogenase. (1036 aa)
LOC106903454E1_dh domain-containing protein. (109 aa)
ENSPMEP00000018203Fumarate hydratase. (482 aa)
LOC106905448Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (366 aa)
LOC106928397E1_dh domain-containing protein. (343 aa)
got1Aspartate aminotransferase. (410 aa)
sdhdSuccinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (157 aa)
gptSi:ch211-217a12.1. (505 aa)
LOC106903771Dihydrolipoamide S-succinyltransferase. (458 aa)
ACLYATP-citrate synthase; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family. (1091 aa)
aco1Aconitase 1, soluble; Belongs to the aconitase/IPM isomerase family. (820 aa)
IDH2Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (453 aa)
mdh1Malate dehydrogenase. (350 aa)
ddoZgc:172341. (338 aa)
ACO2Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (781 aa)
pdhxDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (493 aa)
pdhbPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (357 aa)
agxt2Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (517 aa)
LOC106924537Glutamic pyruvate transaminase (alanine aminotransferase) 2, like. (522 aa)
LOC106930998Aminotran_1_2 domain-containing protein. (492 aa)
dbtDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (492 aa)
csCitrate synthase; Belongs to the citrate synthase family. (469 aa)
Your Current Organism:
Poecilia mexicana
NCBI taxonomy Id: 48701
Other names: shortfin molly
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