(50 nodes) Linoleic acid metabolism, and Lipoxygenase network (Poecilia mexicana)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	alox5	Arachidonate 5-lipoxygenase a. (673 aa)
	LOC106930250	LRAT domain-containing protein. (171 aa)
	LOC106920714	Cytochrome P450, family 2, subfamily N, polypeptide 13; Belongs to the cytochrome P450 family. (507 aa)
	ENSPMEP00000002549	Uncharacterized protein; Belongs to the cytochrome P450 family. (150 aa)
	LOC106906872	LRAT domain-containing protein. (172 aa)
	LOC106928913	Leukotriene C4 synthase. (183 aa)
	lta4h	Leukotriene A(4) hydrolase; Belongs to the peptidase M1 family. (614 aa)
	pla2g4a	Phospholipase A2. (749 aa)
	ENSPMEP00000005437	Uncharacterized protein; Belongs to the cytochrome P450 family. (150 aa)
	LOC106909730	Uncharacterized protein. (578 aa)
	LOC106909732	Lipoxygenase domain-containing protein. (133 aa)
	LOC106906711	Lipoxygenase domain-containing protein. (472 aa)
	LOC106921618	Phospholipase A(2). (149 aa)
	jmjd7	Jumonji domain containing 7. (312 aa)
	LOC106924946	Cytochrome P450, family 4, subfamily F, polypeptide 3; Belongs to the cytochrome P450 family. (590 aa)
	LOC106928763	Si:dkey-17e16.9. (670 aa)
	LOC106928764	Uncharacterized protein. (669 aa)
	LOC106921863	Cytochrome b5 heme-binding domain-containing protein. (445 aa)
	pla2g1b	Phospholipase A(2). (144 aa)
	ENSPMEP00000010623	Phospholipase A(2). (141 aa)
	LOC106925463	Uncharacterized protein. (589 aa)
	alox5ap	Arachidonate 5-lipoxygenase-activating protein. (183 aa)
	LOC106934018	Uncharacterized protein. (546 aa)
	pla2g12b	Phospholipase A2, group XIIB. (204 aa)
	LOC106921860	Cytochrome b5 heme-binding domain-containing protein. (428 aa)
	LOC106904842	Uncharacterized protein; Belongs to the cytochrome P450 family. (500 aa)
	ENSPMEP00000018895	Uncharacterized protein; Belongs to the cytochrome P450 family. (150 aa)
	LOC106908422	Uncharacterized protein; Belongs to the cytochrome P450 family. (498 aa)
	LOC106908423	Uncharacterized protein; Belongs to the cytochrome P450 family. (498 aa)
	LOC106908423-2	Uncharacterized protein; Belongs to the cytochrome P450 family. (497 aa)
	ENSPMEP00000019448	Uncharacterized protein. (102 aa)
	LOC106921805	Uncharacterized protein. (211 aa)
	LOC106922288	Zgc:152891. (620 aa)
	LOC106907495	Protein interacting with cyclin A1. (816 aa)
	pla2g6	Phospholipase A2, group VI (cytosolic, calcium-independent). (799 aa)
	LOC106912355	Uncharacterized protein; Belongs to the cytochrome P450 family. (425 aa)
	ENSPMEP00000024509	Uncharacterized protein. (310 aa)
	ENSPMEP00000024525	Uncharacterized protein; Belongs to the cytochrome P450 family. (473 aa)
	LOC106909731	Uncharacterized protein. (605 aa)
	LOC106933562	Phospholipase A(2). (152 aa)
	LOC106930849	Cytochrome P450, family 2, subfamily U, polypeptide 1; Belongs to the cytochrome P450 family. (539 aa)
	pla2g12a	Phospholipase A2, group XIIA. (198 aa)
	LOC106921859	Fatty acid desaturase 2. (445 aa)
	LOC106917334	Uncharacterized protein. (643 aa)
	LOC106921230	PA2c domain-containing protein. (466 aa)
	ENSPMEP00000033364	Uncharacterized protein. (70 aa)
	LOC106908420	Uncharacterized protein; Belongs to the cytochrome P450 family. (502 aa)
	LOC106908421	Uncharacterized protein; Belongs to the cytochrome P450 family. (497 aa)
	LOC106908424	Cytochrome P450, family 2, subfamily AD, polypeptide 3; Belongs to the cytochrome P450 family. (493 aa)
	LOC106917266	Arachidonate 12-lipoxygenase. (670 aa)

Your Current Organism:

Poecilia mexicana

NCBI taxonomy Id: 48701
Other names: shortfin molly

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPMEP00000002549	ENSPMEP00000005437	ENSPMEP00000002549	ENSPMEP00000005437	Uncharacterized protein; Belongs to the cytochrome P450 family.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.734
ENSPMEP00000002549	ENSPMEP00000010623	ENSPMEP00000002549	ENSPMEP00000010623	Uncharacterized protein; Belongs to the cytochrome P450 family.	Phospholipase A(2).	0.692
ENSPMEP00000002549	ENSPMEP00000024509	ENSPMEP00000002549	ENSPMEP00000024509	Uncharacterized protein; Belongs to the cytochrome P450 family.	Uncharacterized protein.	0.841
ENSPMEP00000002549	ENSPMEP00000024525	ENSPMEP00000002549	ENSPMEP00000024525	Uncharacterized protein; Belongs to the cytochrome P450 family.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.734
ENSPMEP00000002549	LOC106904842	ENSPMEP00000002549	ENSPMEP00000018715	Uncharacterized protein; Belongs to the cytochrome P450 family.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.496
ENSPMEP00000002549	LOC106906711	ENSPMEP00000002549	ENSPMEP00000007058	Uncharacterized protein; Belongs to the cytochrome P450 family.	Lipoxygenase domain-containing protein.	0.490
ENSPMEP00000002549	LOC106906872	ENSPMEP00000002549	ENSPMEP00000002662	Uncharacterized protein; Belongs to the cytochrome P450 family.	LRAT domain-containing protein.	0.815
ENSPMEP00000002549	LOC106907495	ENSPMEP00000002549	ENSPMEP00000021752	Uncharacterized protein; Belongs to the cytochrome P450 family.	Protein interacting with cyclin A1.	0.612
ENSPMEP00000002549	LOC106908420	ENSPMEP00000002549	ENSPMEP00000033376	Uncharacterized protein; Belongs to the cytochrome P450 family.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.472
ENSPMEP00000002549	LOC106908422	ENSPMEP00000002549	ENSPMEP00000019396	Uncharacterized protein; Belongs to the cytochrome P450 family.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.852
ENSPMEP00000002549	LOC106908423	ENSPMEP00000002549	ENSPMEP00000019399	Uncharacterized protein; Belongs to the cytochrome P450 family.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.672
ENSPMEP00000002549	LOC106908423-2	ENSPMEP00000002549	ENSPMEP00000019419	Uncharacterized protein; Belongs to the cytochrome P450 family.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.672
ENSPMEP00000002549	LOC106908424	ENSPMEP00000002549	ENSPMEP00000033719	Uncharacterized protein; Belongs to the cytochrome P450 family.	Cytochrome P450, family 2, subfamily AD, polypeptide 3; Belongs to the cytochrome P450 family.	0.490
ENSPMEP00000002549	LOC106909730	ENSPMEP00000002549	ENSPMEP00000005732	Uncharacterized protein; Belongs to the cytochrome P450 family.	Uncharacterized protein.	0.515
ENSPMEP00000002549	LOC106909731	ENSPMEP00000002549	ENSPMEP00000024636	Uncharacterized protein; Belongs to the cytochrome P450 family.	Uncharacterized protein.	0.834
ENSPMEP00000002549	LOC106909732	ENSPMEP00000002549	ENSPMEP00000005761	Uncharacterized protein; Belongs to the cytochrome P450 family.	Lipoxygenase domain-containing protein.	0.518
ENSPMEP00000002549	LOC106912355	ENSPMEP00000002549	ENSPMEP00000023588	Uncharacterized protein; Belongs to the cytochrome P450 family.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.797
ENSPMEP00000002549	LOC106917266	ENSPMEP00000002549	ENSPMEP00000034287	Uncharacterized protein; Belongs to the cytochrome P450 family.	Arachidonate 12-lipoxygenase.	0.866
ENSPMEP00000002549	LOC106917334	ENSPMEP00000002549	ENSPMEP00000033023	Uncharacterized protein; Belongs to the cytochrome P450 family.	Uncharacterized protein.	0.490
ENSPMEP00000002549	LOC106921230	ENSPMEP00000002549	ENSPMEP00000033175	Uncharacterized protein; Belongs to the cytochrome P450 family.	PA2c domain-containing protein.	0.783