(35 nodes) ER to Golgi transport vesicle membrane network (Poecilia mexicana)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC106933443	Uncharacterized protein. (894 aa)
	LOC106910276	SEC31 homolog B, COPII coat complex component. (1208 aa)
	sec31a	SEC31 homolog A, COPII coat complex component. (1417 aa)
	ENSPMEP00000006373	Uncharacterized protein. (87 aa)
	LOC106929819	SEC22 homolog B, vesicle trafficking protein a; Belongs to the synaptobrevin family. (216 aa)
	VMA21	Vacuolar ATPase assembly integral membrane protein VMA21; Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum; Belongs to the VMA21 family. (132 aa)
	KLHL12	Kelch like family member 12. (598 aa)
	ENSPMEP00000017896	Uncharacterized protein. (192 aa)
	LOC106917941	Secretion associated, Ras related GTPase 1Ab; Belongs to the small GTPase superfamily. SAR1 family. (198 aa)
	LOC106905494	USO1 vesicle transport factor. (939 aa)
	sec16a	Protein transport protein sec16; Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. (2370 aa)
	stx17	Syntaxin 17; Belongs to the syntaxin family. (298 aa)
	gosr2	Golgi SNAP receptor complex member 2; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network. (212 aa)
	vti1b	Vesicle transport through interaction with t-SNAREs 1B. (227 aa)
	LOC106927758	Uncharacterized protein; Belongs to the small GTPase superfamily. SAR1 family. (198 aa)
	sec24c	SEC24 homolog C, COPII coat complex component. (1227 aa)
	LOC106904338	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (764 aa)
	LOC106924918	BTB domain-containing protein. (514 aa)
	LOC106911521	Protein transport protein Sec23B. (766 aa)
	pdcd6	Programmed cell death 6. (188 aa)
	LOC106918678	SEC24 homolog B, COPII coat complex component. (1213 aa)
	LOC106925306	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (766 aa)
	srebf2	Sterol regulatory element binding transcription factor 2. (1175 aa)
	sec13	SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family. (320 aa)
	sec24d	SEC24 homolog D, COPII coat complex component. (1065 aa)
	sec16b	Protein transport protein sec16; Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. (707 aa)
	LOC106928650	USO1 vesicle transport factor. (937 aa)
	sar1b	Secretion associated, Ras related GTPase 1B; Belongs to the small GTPase superfamily. SAR1 family. (198 aa)
	sec24a	SEC24 homolog A, COPII coat complex component. (1090 aa)
	scap	SREBF chaperone. (1291 aa)
	srebf1	Sterol regulatory element binding transcription factor 1. (1184 aa)
	pef1	Penta-EF-hand domain containing 1. (262 aa)
	LOC106904833	VWFA domain-containing protein. (750 aa)
	LOC106931152	SEC22 homolog B, vesicle trafficking protein (gene/pseudogene); Belongs to the synaptobrevin family. (215 aa)
	vti1a	Vesicle transport through interaction with t-SNAREs 1A. (154 aa)

Your Current Organism:

Poecilia mexicana

NCBI taxonomy Id: 48701
Other names: shortfin molly

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPMEP00000006373	ENSPMEP00000017896	ENSPMEP00000006373	ENSPMEP00000017896	Uncharacterized protein.	Uncharacterized protein.	0.858
ENSPMEP00000006373	KLHL12	ENSPMEP00000006373	ENSPMEP00000000742	Uncharacterized protein.	Kelch like family member 12.	0.546
ENSPMEP00000006373	LOC106904338	ENSPMEP00000006373	ENSPMEP00000025515	Uncharacterized protein.	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	0.982
ENSPMEP00000006373	LOC106904833	ENSPMEP00000006373	ENSPMEP00000033359	Uncharacterized protein.	VWFA domain-containing protein.	0.877
ENSPMEP00000006373	LOC106911521	ENSPMEP00000006373	ENSPMEP00000027463	Uncharacterized protein.	Protein transport protein Sec23B.	0.972
ENSPMEP00000006373	LOC106917941	ENSPMEP00000006373	ENSPMEP00000018929	Uncharacterized protein.	Secretion associated, Ras related GTPase 1Ab; Belongs to the small GTPase superfamily. SAR1 family.	0.972
ENSPMEP00000006373	LOC106918678	ENSPMEP00000006373	ENSPMEP00000017079	Uncharacterized protein.	SEC24 homolog B, COPII coat complex component.	0.985
ENSPMEP00000006373	LOC106925306	ENSPMEP00000006373	ENSPMEP00000016300	Uncharacterized protein.	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	0.972
ENSPMEP00000006373	LOC106927758	ENSPMEP00000006373	ENSPMEP00000021474	Uncharacterized protein.	Uncharacterized protein; Belongs to the small GTPase superfamily. SAR1 family.	0.972
ENSPMEP00000006373	LOC106929819	ENSPMEP00000006373	ENSPMEP00000003149	Uncharacterized protein.	SEC22 homolog B, vesicle trafficking protein a; Belongs to the synaptobrevin family.	0.723
ENSPMEP00000006373	LOC106931152	ENSPMEP00000006373	ENSPMEP00000017333	Uncharacterized protein.	SEC22 homolog B, vesicle trafficking protein (gene/pseudogene); Belongs to the synaptobrevin family.	0.723
ENSPMEP00000006373	LOC106933443	ENSPMEP00000006373	ENSPMEP00000012930	Uncharacterized protein.	Uncharacterized protein.	0.953
ENSPMEP00000006373	gosr2	ENSPMEP00000006373	ENSPMEP00000020838	Uncharacterized protein.	Golgi SNAP receptor complex member 2; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network.	0.667
ENSPMEP00000006373	pdcd6	ENSPMEP00000006373	ENSPMEP00000028209	Uncharacterized protein.	Programmed cell death 6.	0.718
ENSPMEP00000006373	pef1	ENSPMEP00000006373	ENSPMEP00000032617	Uncharacterized protein.	Penta-EF-hand domain containing 1.	0.752
ENSPMEP00000006373	sar1b	ENSPMEP00000006373	ENSPMEP00000030434	Uncharacterized protein.	Secretion associated, Ras related GTPase 1B; Belongs to the small GTPase superfamily. SAR1 family.	0.972
ENSPMEP00000006373	sec13	ENSPMEP00000006373	ENSPMEP00000015693	Uncharacterized protein.	SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family.	0.991
ENSPMEP00000006373	sec16a	ENSPMEP00000006373	ENSPMEP00000019063	Uncharacterized protein.	Protein transport protein sec16; Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus.	0.877
ENSPMEP00000006373	sec16b	ENSPMEP00000006373	ENSPMEP00000011787	Uncharacterized protein.	Protein transport protein sec16; Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus.	0.858
ENSPMEP00000006373	sec24a	ENSPMEP00000006373	ENSPMEP00000030448	Uncharacterized protein.	SEC24 homolog A, COPII coat complex component.	0.986