(80 nodes) Antioxidant activity network (Poecilia mexicana)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	cat	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (527 aa)
	mgst1	Microsomal glutathione S-transferase 1.2. (152 aa)
	nxnl2	Nucleoredoxin like 2. (156 aa)
	LOC106926317	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (112 aa)
	prdx3	Peroxiredoxin 3. (248 aa)
	txnl1	Thioredoxin-like 1. (289 aa)
	selenot	Selenoprotein T; Belongs to the SelWTH family. Selenoprotein T subfamily. (190 aa)
	nox5	NADPH oxidase, EF-hand calcium binding domain 5. (700 aa)
	LOC106933565	Uncharacterized protein. (446 aa)
	LOC106925039	Thioredoxin reductase 3. (600 aa)
	rttn	Rotatin. (2247 aa)
	LOC106907371	Uncharacterized protein; Belongs to the GST superfamily. (239 aa)
	LOC106907378	Uncharacterized protein. (239 aa)
	SOD1	Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (154 aa)
	LOC106907374	Uncharacterized protein. (239 aa)
	LOC106922038	Nucleoredoxin like 1. (232 aa)
	nxnl1	Nucleoredoxin like 1. (221 aa)
	LOC106919016	Peroxiredoxin 1. (199 aa)
	mgst2	Uncharacterized protein. (136 aa)
	txnrd2	Thioredoxin reductase 2, tandem duplicate 1. (512 aa)
	srxn1	Sulfiredoxin. (149 aa)
	LOC106921903	Peroxiredoxin 4. (261 aa)
	LOC106918488	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (142 aa)
	LOC106919036	Thioredoxin domain-containing protein. (258 aa)
	LOC106923740	Glutathione peroxidase 1a. (178 aa)
	LOC106923731	Prostaglandin-endoperoxide synthase 1. (600 aa)
	PRDX2	Peroxiredoxin 2. (197 aa)
	LOC106928913	Leukotriene C4 synthase. (183 aa)
	ptgs2	Prostaglandin-endoperoxide synthase 2b. (615 aa)
	ubiad1	UbiA prenyltransferase domain containing 1. (354 aa)
	LOC106920394	BTB domain containing 6. (557 aa)
	LOC106926376	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (146 aa)
	gpx4	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (184 aa)
	LOC106920856	Si:ch211-175m2.5. (247 aa)
	ptges	Prostaglandin E synthase. (146 aa)
	ENSPMEP00000008176	Uncharacterized protein. (72 aa)
	prxl2c	Peroxiredoxin like 2C. (230 aa)
	LOC106918210	Microsomal glutathione S-transferase 3b. (140 aa)
	ENSPMEP00000010683	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (135 aa)
	prdx6	Peroxiredoxin 6. (227 aa)
	LOC106929649	C1q domain-containing protein. (618 aa)
	prdx5	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (190 aa)
	gstk1	Glutathione S-transferase kappa. (228 aa)
	LOC106915305	Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (243 aa)
	pxdn	Peroxidasin. (1571 aa)
	ENSPMEP00000020334	Eosinophil peroxidase. (397 aa)
	ptgs1	Prostaglandin-endoperoxide synthase 1. (595 aa)
	glrx	Glutaredoxin (thioltransferase). (106 aa)
	mfsd11	Major facilitator superfamily domain containing 11. (454 aa)
	yipf5	Protein YIPF. (257 aa)
	LOC106923283	Uncharacterized protein. (264 aa)
	LOC106932168	Zgc:123321. (235 aa)
	sod3	Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (215 aa)
	LOC106908506	Apolipoprotein Eb. (265 aa)
	TPO	Thyroid peroxidase. (832 aa)
	GPX2	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (142 aa)
	LOC106905631	BTB (POZ) domain containing 6b. (479 aa)
	LOC106921392	Uncharacterized protein. (135 aa)
	selenos	Selenoprotein S. (190 aa)
	ENSPMEP00000010701	Uncharacterized protein. (72 aa)
	gsr	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (507 aa)
	LOC106923631	Apolipoprotein Ea. (251 aa)
	ENSPMEP00000034289	Peptidase S1 domain-containing protein. (302 aa)
	nxn	Thioredoxin domain-containing protein. (418 aa)
	txndc17	Thioredoxin domain containing 17. (123 aa)
	ENSPMEP00000033071	annotation not available (72 aa)
	LOC106918624	Phospholipid hydroperoxide glutathione peroxidase, mitochondrial-like. (112 aa)
	LOC106914095	Superoxide dismutase [Cu-Zn]-like. (154 aa)
	LOC106918076	Selenoprotein U 1a. (210 aa)
	LOC106919349	Dual oxidase. (1497 aa)
	ENSPMEP00000030266	Uncharacterized protein. (406 aa)
	ENSPMEP00000030053	Uncharacterized protein. (73 aa)
	gpx8	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (210 aa)
	tp53inp1	Tumor protein p53 inducible nuclear protein 1. (295 aa)
	ptges2	Prostaglandin E synthase 2-like; Belongs to the GST superfamily. (378 aa)
	tmem221	Si:ch211-125m10.6. (305 aa)
	LOC106925485	Myeloid-specific peroxidase. (826 aa)
	mgst3	Microsomal glutathione S-transferase 3a. (154 aa)
	sod2	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (225 aa)
	LOC106922887	Selenoprotein T; Belongs to the SelWTH family. Selenoprotein T subfamily. (204 aa)

Your Current Organism:

Poecilia mexicana

NCBI taxonomy Id: 48701
Other names: shortfin molly

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPMEP00000008176	ENSPMEP00000010683	ENSPMEP00000008176	ENSPMEP00000010683	Uncharacterized protein.	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	0.784
ENSPMEP00000008176	GPX2	ENSPMEP00000008176	ENSPMEP00000015796	Uncharacterized protein.	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	0.605
ENSPMEP00000008176	LOC106907371	ENSPMEP00000008176	ENSPMEP00000024580	Uncharacterized protein.	Uncharacterized protein; Belongs to the GST superfamily.	0.776
ENSPMEP00000008176	LOC106907374	ENSPMEP00000008176	ENSPMEP00000024314	Uncharacterized protein.	Uncharacterized protein.	0.786
ENSPMEP00000008176	LOC106907378	ENSPMEP00000008176	ENSPMEP00000024579	Uncharacterized protein.	Uncharacterized protein.	0.786
ENSPMEP00000008176	LOC106914095	ENSPMEP00000008176	ENSPMEP00000031047	Uncharacterized protein.	Superoxide dismutase [Cu-Zn]-like.	0.717
ENSPMEP00000008176	LOC106915305	ENSPMEP00000008176	ENSPMEP00000020720	Uncharacterized protein.	Chloride intracellular channel protein; Belongs to the chloride channel CLIC family.	0.426
ENSPMEP00000008176	LOC106918210	ENSPMEP00000008176	ENSPMEP00000009386	Uncharacterized protein.	Microsomal glutathione S-transferase 3b.	0.690
ENSPMEP00000008176	LOC106918488	ENSPMEP00000008176	ENSPMEP00000001481	Uncharacterized protein.	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	0.796
ENSPMEP00000008176	LOC106919016	ENSPMEP00000008176	ENSPMEP00000023065	Uncharacterized protein.	Peroxiredoxin 1.	0.643
ENSPMEP00000008176	LOC106919036	ENSPMEP00000008176	ENSPMEP00000003033	Uncharacterized protein.	Thioredoxin domain-containing protein.	0.862
ENSPMEP00000008176	LOC106921903	ENSPMEP00000008176	ENSPMEP00000000751	Uncharacterized protein.	Peroxiredoxin 4.	0.650
ENSPMEP00000008176	LOC106923740	ENSPMEP00000008176	ENSPMEP00000003178	Uncharacterized protein.	Glutathione peroxidase 1a.	0.637
ENSPMEP00000008176	LOC106925039	ENSPMEP00000008176	ENSPMEP00000024889	Uncharacterized protein.	Thioredoxin reductase 3.	0.664
ENSPMEP00000008176	LOC106926376	ENSPMEP00000008176	ENSPMEP00000006432	Uncharacterized protein.	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	0.784
ENSPMEP00000008176	LOC106928913	ENSPMEP00000008176	ENSPMEP00000004442	Uncharacterized protein.	Leukotriene C4 synthase.	0.529
ENSPMEP00000008176	PRDX2	ENSPMEP00000008176	ENSPMEP00000003337	Uncharacterized protein.	Peroxiredoxin 2.	0.643
ENSPMEP00000008176	SOD1	ENSPMEP00000008176	ENSPMEP00000024363	Uncharacterized protein.	Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family.	0.717
ENSPMEP00000008176	cat	ENSPMEP00000008176	ENSPMEP00000027352	Uncharacterized protein.	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	0.621
ENSPMEP00000008176	glrx	ENSPMEP00000008176	ENSPMEP00000018162	Uncharacterized protein.	Glutaredoxin (thioltransferase).	0.696