(21 nodes) Ionotropic glutamate receptor binding network (Poecilia mexicana)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC106906167	Neuropilin (NRP) and tolloid (TLL)-like 2b. (525 aa)
	igsf11	Immunoglobulin superfamily member 11. (419 aa)
	LOC106917306	Uncharacterized protein. (1425 aa)
	LOC106923898	Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (317 aa)
	nsf	N-ethylmaleimide-sensitive factor a. (743 aa)
	neto1	Neuropilin (NRP) and tolloid (TLL)-like 1, like. (552 aa)
	ENSPMEP00000027846	Uncharacterized protein. (102 aa)
	LOC106907318	PDZ domain-containing protein. (295 aa)
	ENSPMEP00000025183	N-ethylmaleimide sensitive factor, vesicle fusing ATPase. (236 aa)
	neto2	Neuropilin (NRP) and tolloid (TLL)-like 2b. (514 aa)
	LOC106929678	Protein shisa-7-like. (703 aa)
	ENSPMEP00000020237	Uncharacterized protein. (226 aa)
	shank1	SH3 and multiple ankyrin repeat domains 1. (786 aa)
	ENSPMEP00000018887	Uncharacterized protein. (1669 aa)
	LOC106925393	Shisa family member 7a. (703 aa)
	LOC106924067	Neuropilin (NRP) and tolloid (TLL)-like 1. (570 aa)
	cacng4	Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (333 aa)
	LOC106919657	Shisa family member 7. (656 aa)
	ENSPMEP00000006476	Uncharacterized protein. (139 aa)
	ENSPMEP00000005078	Uncharacterized protein. (140 aa)
	cacng3	Calcium voltage-gated channel auxiliary subunit gamma 3. (315 aa)

Your Current Organism:

Poecilia mexicana

NCBI taxonomy Id: 48701
Other names: shortfin molly

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPMEP00000018887	LOC106907318	ENSPMEP00000018887	ENSPMEP00000025542	Uncharacterized protein.	PDZ domain-containing protein.	0.783
ENSPMEP00000018887	LOC106917306	ENSPMEP00000018887	ENSPMEP00000033831	Uncharacterized protein.	Uncharacterized protein.	0.649
ENSPMEP00000018887	shank1	ENSPMEP00000018887	ENSPMEP00000019135	Uncharacterized protein.	SH3 and multiple ankyrin repeat domains 1.	0.656
LOC106907318	ENSPMEP00000018887	ENSPMEP00000025542	ENSPMEP00000018887	PDZ domain-containing protein.	Uncharacterized protein.	0.783
LOC106907318	LOC106917306	ENSPMEP00000025542	ENSPMEP00000033831	PDZ domain-containing protein.	Uncharacterized protein.	0.783
LOC106907318	shank1	ENSPMEP00000025542	ENSPMEP00000019135	PDZ domain-containing protein.	SH3 and multiple ankyrin repeat domains 1.	0.783
LOC106917306	ENSPMEP00000018887	ENSPMEP00000033831	ENSPMEP00000018887	Uncharacterized protein.	Uncharacterized protein.	0.649
LOC106917306	LOC106907318	ENSPMEP00000033831	ENSPMEP00000025542	Uncharacterized protein.	PDZ domain-containing protein.	0.783
LOC106917306	LOC106919657	ENSPMEP00000033831	ENSPMEP00000008354	Uncharacterized protein.	Shisa family member 7.	0.442
LOC106917306	shank1	ENSPMEP00000033831	ENSPMEP00000019135	Uncharacterized protein.	SH3 and multiple ankyrin repeat domains 1.	0.649
LOC106919657	LOC106917306	ENSPMEP00000008354	ENSPMEP00000033831	Shisa family member 7.	Uncharacterized protein.	0.442
shank1	ENSPMEP00000018887	ENSPMEP00000019135	ENSPMEP00000018887	SH3 and multiple ankyrin repeat domains 1.	Uncharacterized protein.	0.656
shank1	LOC106907318	ENSPMEP00000019135	ENSPMEP00000025542	SH3 and multiple ankyrin repeat domains 1.	PDZ domain-containing protein.	0.783
shank1	LOC106917306	ENSPMEP00000019135	ENSPMEP00000033831	SH3 and multiple ankyrin repeat domains 1.	Uncharacterized protein.	0.649