(45 nodes) Cellular response to glucose starvation network (Poecilia mexicana)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	bcl2	BCL2 apoptosis regulator b. (229 aa)
	prkag1	Protein kinase, AMP-activated, gamma 1 non-catalytic subunit. (334 aa)
	LOC106917338	Protein kinase domain-containing protein. (749 aa)
	nim1k	NIM1 serine/threonine protein kinase; Belongs to the protein kinase superfamily. (475 aa)
	eif2ak3	Eukaryotic translation initiation factor 2-alpha kinase 3. (1034 aa)
	prkag3	Protein kinase, AMP-activated, gamma 3a non-catalytic subunit. (353 aa)
	LOC106918361	Si:ch211-117c9.1. (696 aa)
	pik3c3	Phosphatidylinositol 3-kinase catalytic subunit type 3. (876 aa)
	nfe2l2	Nuclear factor, erythroid 2-like 2a. (617 aa)
	LOC106919797	Protein kinase, AMP-activated, gamma 2 non-catalytic subunit b. (544 aa)
	LOC106930974	Protein kinase, AMP-activated, gamma 3b non-catalytic subunit. (392 aa)
	nuak2	NUAK family, SNF1-like kinase, 2. (606 aa)
	LOC106921770	Cytoplasmic polyadenylation element binding protein 4a. (763 aa)
	LOC106906109	Protein kinase domain-containing protein. (733 aa)
	prkaa1	Non-specific serine/threonine protein kinase. (564 aa)
	ENSPMEP00000023142	Uncharacterized protein. (160 aa)
	atg14	Autophagy related 14. (378 aa)
	LOC106911661	Uncharacterized protein. (690 aa)
	ENSPMEP00000032173	Protein kinase domain-containing protein. (200 aa)
	LOC106904521	Transducin (beta)-like 2. (441 aa)
	sik2	Salt-inducible kinase 2b. (926 aa)
	bhlha15	Basic helix-loop-helix family, member a15. (191 aa)
	itfg2	Integrin alpha FG-GAP repeat containing 2. (457 aa)
	prkaa2	Non-specific serine/threonine protein kinase. (555 aa)
	pik3r4	Phosphoinositide-3-kinase, regulatory subunit 4. (1325 aa)
	rrp8	Ribosomal RNA-processing protein 8; Probable methyltransferase required to silence rDNA. Belongs to the methyltransferase superfamily. RRP8 family. (548 aa)
	sesn1	Sestrin 1. (545 aa)
	xbp1	X-box binding protein 1. (263 aa)
	sirt1	Sirtuin 1. (677 aa)
	LOC106927560	Salt-inducible kinase 1. (806 aa)
	LOC106910308	Si:dkey-206d17.12. (556 aa)
	hspa5	Heat shock protein 5; Belongs to the heat shock protein 70 family. (652 aa)
	LOC106920290	Si:zfos-80g12.1. (444 aa)
	impact	Impact RWD domain protein. (317 aa)
	LOC106932732	Si:dkey-16p21.7. (640 aa)
	LOC106906194	Zinc finger CCCH-type containing 12A. (627 aa)
	LOC106912004	Transducin beta-like protein 2. (441 aa)
	LOC106926767	Si:ch211-22d5.2; Belongs to the protein kinase superfamily. (435 aa)
	LOC106931862	Sestrin 2. (557 aa)
	LOC106929941	NUAK family, SNF1-like kinase, 1b. (661 aa)
	ENSPMEP00000013515	Protein kinase domain-containing protein. (394 aa)
	kptn	Kaptin (actin binding protein). (440 aa)
	LOC106925402	Uncharacterized protein. (866 aa)
	LOC106922705	Si:ch211-125a15.1. (451 aa)
	pick1	Protein interacting with prkca 1. (409 aa)

Your Current Organism:

Poecilia mexicana

NCBI taxonomy Id: 48701
Other names: shortfin molly

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPMEP00000013515	LOC106911661	ENSPMEP00000013515	ENSPMEP00000033865	Protein kinase domain-containing protein.	Uncharacterized protein.	0.643
ENSPMEP00000013515	LOC106918361	ENSPMEP00000013515	ENSPMEP00000005480	Protein kinase domain-containing protein.	Si:ch211-117c9.1.	0.451
ENSPMEP00000013515	LOC106919797	ENSPMEP00000013515	ENSPMEP00000004377	Protein kinase domain-containing protein.	Protein kinase, AMP-activated, gamma 2 non-catalytic subunit b.	0.643
ENSPMEP00000013515	LOC106929941	ENSPMEP00000013515	ENSPMEP00000013305	Protein kinase domain-containing protein.	NUAK family, SNF1-like kinase, 1b.	0.431
ENSPMEP00000013515	LOC106930974	ENSPMEP00000013515	ENSPMEP00000003838	Protein kinase domain-containing protein.	Protein kinase, AMP-activated, gamma 3b non-catalytic subunit.	0.643
ENSPMEP00000013515	nuak2	ENSPMEP00000013515	ENSPMEP00000003485	Protein kinase domain-containing protein.	NUAK family, SNF1-like kinase, 2.	0.448
ENSPMEP00000013515	pik3c3	ENSPMEP00000013515	ENSPMEP00000005138	Protein kinase domain-containing protein.	Phosphatidylinositol 3-kinase catalytic subunit type 3.	0.580
ENSPMEP00000013515	pik3r4	ENSPMEP00000013515	ENSPMEP00000028202	Protein kinase domain-containing protein.	Phosphoinositide-3-kinase, regulatory subunit 4.	0.584
ENSPMEP00000013515	prkag1	ENSPMEP00000013515	ENSPMEP00000017751	Protein kinase domain-containing protein.	Protein kinase, AMP-activated, gamma 1 non-catalytic subunit.	0.643
ENSPMEP00000013515	prkag3	ENSPMEP00000013515	ENSPMEP00000006005	Protein kinase domain-containing protein.	Protein kinase, AMP-activated, gamma 3a non-catalytic subunit.	0.643
ENSPMEP00000032173	LOC106911661	ENSPMEP00000032173	ENSPMEP00000033865	Protein kinase domain-containing protein.	Uncharacterized protein.	0.643
ENSPMEP00000032173	LOC106918361	ENSPMEP00000032173	ENSPMEP00000005480	Protein kinase domain-containing protein.	Si:ch211-117c9.1.	0.418
ENSPMEP00000032173	LOC106919797	ENSPMEP00000032173	ENSPMEP00000004377	Protein kinase domain-containing protein.	Protein kinase, AMP-activated, gamma 2 non-catalytic subunit b.	0.643
ENSPMEP00000032173	LOC106929941	ENSPMEP00000032173	ENSPMEP00000013305	Protein kinase domain-containing protein.	NUAK family, SNF1-like kinase, 1b.	0.414
ENSPMEP00000032173	LOC106930974	ENSPMEP00000032173	ENSPMEP00000003838	Protein kinase domain-containing protein.	Protein kinase, AMP-activated, gamma 3b non-catalytic subunit.	0.643
ENSPMEP00000032173	nuak2	ENSPMEP00000032173	ENSPMEP00000003485	Protein kinase domain-containing protein.	NUAK family, SNF1-like kinase, 2.	0.420
ENSPMEP00000032173	pik3c3	ENSPMEP00000032173	ENSPMEP00000005138	Protein kinase domain-containing protein.	Phosphatidylinositol 3-kinase catalytic subunit type 3.	0.580
ENSPMEP00000032173	pik3r4	ENSPMEP00000032173	ENSPMEP00000028202	Protein kinase domain-containing protein.	Phosphoinositide-3-kinase, regulatory subunit 4.	0.584
ENSPMEP00000032173	prkag1	ENSPMEP00000032173	ENSPMEP00000017751	Protein kinase domain-containing protein.	Protein kinase, AMP-activated, gamma 1 non-catalytic subunit.	0.643
ENSPMEP00000032173	prkag3	ENSPMEP00000032173	ENSPMEP00000006005	Protein kinase domain-containing protein.	Protein kinase, AMP-activated, gamma 3a non-catalytic subunit.	0.643