(16 nodes) Dynein heavy chain binding network (Poecilia mexicana)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	wdr34	WD repeat domain 34. (502 aa)
	dnai1	Dynein, axonemal, intermediate chain 1, paralog 2. (611 aa)
	LOC106921027	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (484 aa)
	ENSPMEP00000005594	Uncharacterized protein. (132 aa)
	ENSPMEP00000005608	WD_REPEATS_REGION domain-containing protein. (310 aa)
	ENSPMEP00000009594	WD_REPEATS_REGION domain-containing protein. (675 aa)
	wdr60	WD repeat domain 60. (1030 aa)
	dnal1	Dynein, axonemal, light chain 1. (187 aa)
	dnali1	Dynein, axonemal, light intermediate chain 1. (255 aa)
	ENSPMEP00000022367	WD_REPEATS_REGION domain-containing protein. (188 aa)
	LOC106932927	Dynein, cytoplasmic 1, intermediate chain 2a. (608 aa)
	dync1li2	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (489 aa)
	dnai2	Dynein, axonemal, intermediate chain 2b. (561 aa)
	dync2li1	Dynein, cytoplasmic 2, light intermediate chain 1. (357 aa)
	LOC106934095	Dynein, cytoplasmic 1, intermediate chain 2b. (610 aa)
	ENSPMEP00000030956	Uncharacterized protein. (111 aa)

Your Current Organism:

Poecilia mexicana

NCBI taxonomy Id: 48701
Other names: shortfin molly

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPMEP00000005594	LOC106921027	ENSPMEP00000005594	ENSPMEP00000001151	Uncharacterized protein.	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.	0.957
ENSPMEP00000005594	LOC106932927	ENSPMEP00000005594	ENSPMEP00000023122	Uncharacterized protein.	Dynein, cytoplasmic 1, intermediate chain 2a.	0.879
ENSPMEP00000005594	LOC106934095	ENSPMEP00000005594	ENSPMEP00000030943	Uncharacterized protein.	Dynein, cytoplasmic 1, intermediate chain 2b.	0.879
ENSPMEP00000005594	dnali1	ENSPMEP00000005594	ENSPMEP00000016447	Uncharacterized protein.	Dynein, axonemal, light intermediate chain 1.	0.587
ENSPMEP00000005594	dync1li2	ENSPMEP00000005594	ENSPMEP00000025695	Uncharacterized protein.	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.	0.959
ENSPMEP00000005594	dync2li1	ENSPMEP00000005594	ENSPMEP00000030136	Uncharacterized protein.	Dynein, cytoplasmic 2, light intermediate chain 1.	0.828
ENSPMEP00000005608	LOC106921027	ENSPMEP00000005608	ENSPMEP00000001151	WD_REPEATS_REGION domain-containing protein.	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.	0.957
ENSPMEP00000005608	LOC106932927	ENSPMEP00000005608	ENSPMEP00000023122	WD_REPEATS_REGION domain-containing protein.	Dynein, cytoplasmic 1, intermediate chain 2a.	0.878
ENSPMEP00000005608	LOC106934095	ENSPMEP00000005608	ENSPMEP00000030943	WD_REPEATS_REGION domain-containing protein.	Dynein, cytoplasmic 1, intermediate chain 2b.	0.878
ENSPMEP00000005608	dnali1	ENSPMEP00000005608	ENSPMEP00000016447	WD_REPEATS_REGION domain-containing protein.	Dynein, axonemal, light intermediate chain 1.	0.587
ENSPMEP00000005608	dync1li2	ENSPMEP00000005608	ENSPMEP00000025695	WD_REPEATS_REGION domain-containing protein.	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.	0.959
ENSPMEP00000005608	dync2li1	ENSPMEP00000005608	ENSPMEP00000030136	WD_REPEATS_REGION domain-containing protein.	Dynein, cytoplasmic 2, light intermediate chain 1.	0.828
ENSPMEP00000009594	LOC106921027	ENSPMEP00000009594	ENSPMEP00000001151	WD_REPEATS_REGION domain-containing protein.	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.	0.760
ENSPMEP00000009594	dnal1	ENSPMEP00000009594	ENSPMEP00000011823	WD_REPEATS_REGION domain-containing protein.	Dynein, axonemal, light chain 1.	0.419
ENSPMEP00000009594	dnali1	ENSPMEP00000009594	ENSPMEP00000016447	WD_REPEATS_REGION domain-containing protein.	Dynein, axonemal, light intermediate chain 1.	0.587
ENSPMEP00000009594	dync1li2	ENSPMEP00000009594	ENSPMEP00000025695	WD_REPEATS_REGION domain-containing protein.	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.	0.760
ENSPMEP00000009594	dync2li1	ENSPMEP00000009594	ENSPMEP00000030136	WD_REPEATS_REGION domain-containing protein.	Dynein, cytoplasmic 2, light intermediate chain 1.	0.789
ENSPMEP00000022367	LOC106921027	ENSPMEP00000022367	ENSPMEP00000001151	WD_REPEATS_REGION domain-containing protein.	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.	0.760
ENSPMEP00000022367	dnali1	ENSPMEP00000022367	ENSPMEP00000016447	WD_REPEATS_REGION domain-containing protein.	Dynein, axonemal, light intermediate chain 1.	0.658
ENSPMEP00000022367	dync1li2	ENSPMEP00000022367	ENSPMEP00000025695	WD_REPEATS_REGION domain-containing protein.	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.	0.760