(13 nodes) Spleen development network (Poecilia mexicana)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	nkx2-5	NK2 homeobox 5. (318 aa)
	NKX2-3	NK2 homeobox 3. (364 aa)
	LOC106906322	Uncharacterized protein; Belongs to the protein kinase superfamily. (441 aa)
	rc3h1	Ring finger and CCCH-type domains 1b. (1120 aa)
	bcl2l11	Uncharacterized protein. (241 aa)
	rc3h2	Ring finger and CCCH-type domains 2. (1109 aa)
	wdr55	WD repeat-containing protein 55; Nucleolar protein that acts as a modulator of rRNA synthesis. Plays a central role during organogenesis. Belongs to the WD repeat WDR55 family. (415 aa)
	fadd	DED domain-containing protein. (154 aa)
	LOC106903329	SEFIR domain-containing protein. (407 aa)
	nkx2-3	NK2 homeobox 3. (352 aa)
	LOC106933514	TRAF3 interacting protein 2-like. (432 aa)
	tcf21	Transcription factor 21. (175 aa)
	fadd-2	Uncharacterized protein. (236 aa)

Your Current Organism:

Poecilia mexicana

NCBI taxonomy Id: 48701
Other names: shortfin molly

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC106906322	fadd	ENSPMEP00000003287	ENSPMEP00000019233	Uncharacterized protein; Belongs to the protein kinase superfamily.	DED domain-containing protein.	0.970
LOC106906322	fadd-2	ENSPMEP00000003287	ENSPMEP00000033616	Uncharacterized protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.970
fadd	LOC106906322	ENSPMEP00000019233	ENSPMEP00000003287	DED domain-containing protein.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.970
fadd-2	LOC106906322	ENSPMEP00000033616	ENSPMEP00000003287	Uncharacterized protein.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.970
nkx2-5	tcf21	ENSPMEP00000022530	ENSPMEP00000029783	NK2 homeobox 5.	Transcription factor 21.	0.506
rc3h1	rc3h2	ENSPMEP00000007085	ENSPMEP00000012053	Ring finger and CCCH-type domains 1b.	Ring finger and CCCH-type domains 2.	0.799
rc3h2	rc3h1	ENSPMEP00000012053	ENSPMEP00000007085	Ring finger and CCCH-type domains 2.	Ring finger and CCCH-type domains 1b.	0.799
tcf21	nkx2-5	ENSPMEP00000029783	ENSPMEP00000022530	Transcription factor 21.	NK2 homeobox 5.	0.506