STRINGSTRING
LOC106903560 LOC106903560 LOC106920633 LOC106920633 LOC106909302 LOC106909302 hhip hhip sfrp2 sfrp2 dlg5 dlg5 LOC106927838 LOC106927838 mks1 mks1 TGFBR2 TGFBR2 wnt6 wnt6 ctnnbip1 ctnnbip1 tmem59l tmem59l lrp6 lrp6 SMAD4 SMAD4 nrarp nrarp med1 med1 LOC106903221 LOC106903221 gdnf gdnf ILK ILK sars1 sars1 LOC106925627 LOC106925627 ENSPMEP00000026667 ENSPMEP00000026667 timeless timeless LOC106923514 LOC106923514 pkd1 pkd1 ilk ilk tcf21 tcf21 ppp3r1 ppp3r1 LOC106931781 LOC106931781 LOC106919274 LOC106919274 LOC106919996 LOC106919996 LOC106929752 LOC106929752 LOC106931238 LOC106931238 LOC106917549 LOC106917549 LOC106929094 LOC106929094 edn1 edn1 gbx2 gbx2 LOC106911519 LOC106911519 spry1 spry1 ctsz ctsz LOC106930956 LOC106930956 LOC106932859 LOC106932859 ENSPMEP00000004999 ENSPMEP00000004999 srf srf greb1 greb1 ar ar lef1 lef1 LOC106920283 LOC106920283 LOC106928804 LOC106928804 wt1 wt1 LOC106908804 LOC106908804 LOC106925465 LOC106925465 LOC106907870 LOC106907870 ctsh ctsh LOC106909474 LOC106909474
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC106903560Nuclear factor of activated T cells 4. (891 aa)
LOC106920633Sprouty RTK signaling antagonist 2. (347 aa)
LOC106909302Mothers against decapentaplegic homolog. (534 aa)
hhipHedgehog interacting protein. (697 aa)
sfrp2Secreted frizzled-related protein 2. (295 aa)
dlg5Discs, large homolog 5a (Drosophila); Belongs to the MAGUK family. (2067 aa)
LOC106927838Uncharacterized protein. (341 aa)
mks1MKS transition zone complex subunit 1. (492 aa)
TGFBR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (547 aa)
wnt6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
ctnnbip1Catenin, beta interacting protein 1. (81 aa)
tmem59lTransmembrane protein 59-like. (340 aa)
lrp6Low density lipoprotein receptor-related protein 6. (1608 aa)
SMAD4Mothers against decapentaplegic homolog. (510 aa)
nrarpNOTCH regulated ankyrin repeat protein a. (112 aa)
med1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1793 aa)
LOC106903221Androgen receptor beta. (755 aa)
gdnfGlial cell line-derived neurotrophic factor; Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high- affinity dopamine uptake. (254 aa)
ILKIntegrin linked kinase. (452 aa)
sars1Seryl-tRNA synthetase. (503 aa)
LOC106925627Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (163 aa)
ENSPMEP00000026667Uncharacterized protein. (565 aa)
timelessTimeless circadian clock. (1250 aa)
LOC106923514Mothers against decapentaplegic homolog. (503 aa)
pkd1Polycystic kidney disease 1a. (4429 aa)
ilkUncharacterized protein. (452 aa)
tcf21Transcription factor 21. (175 aa)
ppp3r1Uncharacterized protein. (160 aa)
LOC106931781MADS-box domain-containing protein. (472 aa)
LOC106919274Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (184 aa)
LOC106919996Transforming growth factor beta; Belongs to the TGF-beta family. (380 aa)
LOC106929752Dystroglycan 1. (892 aa)
LOC106931238WT1 transcription factor a. (445 aa)
LOC106917549TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (593 aa)
LOC106929094Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (306 aa)
edn1Endothelin 1. (207 aa)
gbx2Gastrulation brain homeobox 2. (342 aa)
LOC106911519Uncharacterized protein. (186 aa)
spry1Sprouty homolog 1, antagonist of FGF signaling (Drosophila). (358 aa)
ctszCathepsin Z; Belongs to the peptidase C1 family. (303 aa)
LOC106930956Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (362 aa)
LOC106932859NK3 homeobox 1. (196 aa)
ENSPMEP00000004999Musculin (activated B-cell factor-1). (163 aa)
srfSerum response factor b. (601 aa)
greb1Growth regulating estrogen receptor binding 1. (1998 aa)
arUncharacterized protein. (681 aa)
lef1Lymphoid enhancer-binding factor 1. (364 aa)
LOC106920283Heparan-sulfate 6-O-sulfotransferase; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate. (456 aa)
LOC106928804Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family. (469 aa)
wt1WT1 transcription factor b. (422 aa)
LOC106908804Peptidase S72 domain-containing protein. (907 aa)
LOC106925465Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family. (444 aa)
LOC106907870Colony stimulating factor 1b (macrophage). (291 aa)
ctshCathepsin H; Belongs to the peptidase C1 family. (325 aa)
LOC106909474Low density lipoprotein receptor-related protein 5. (1600 aa)
Your Current Organism:
Poecilia mexicana
NCBI taxonomy Id: 48701
Other names: shortfin molly
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.