node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ENSPMEP00000007622 | ENSPMEP00000025026 | ENSPMEP00000007622 | ENSPMEP00000025026 | Iron-sulfur cluster assembly enzyme b; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | Frataxin. | 0.979 |
ENSPMEP00000007622 | LOC106918392 | ENSPMEP00000007622 | ENSPMEP00000023730 | Iron-sulfur cluster assembly enzyme b; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | BolA family member 2; Belongs to the BolA/IbaG family. | 0.439 |
ENSPMEP00000007622 | LOC106928075 | ENSPMEP00000007622 | ENSPMEP00000005232 | Iron-sulfur cluster assembly enzyme b; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). | 0.589 |
ENSPMEP00000007622 | SDHB | ENSPMEP00000007622 | ENSPMEP00000001618 | Iron-sulfur cluster assembly enzyme b; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). | 0.589 |
ENSPMEP00000007622 | ciapin1 | ENSPMEP00000007622 | ENSPMEP00000000869 | Iron-sulfur cluster assembly enzyme b; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | Anamorsin; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electron [...] | 0.486 |
ENSPMEP00000007622 | fdx1 | ENSPMEP00000007622 | ENSPMEP00000006794 | Iron-sulfur cluster assembly enzyme b; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | 2Fe-2S ferredoxin-type domain-containing protein. | 0.934 |
ENSPMEP00000007622 | fdx2 | ENSPMEP00000007622 | ENSPMEP00000007066 | Iron-sulfur cluster assembly enzyme b; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | Ferredoxin 2. | 0.936 |
ENSPMEP00000007622 | fech | ENSPMEP00000007622 | ENSPMEP00000013827 | Iron-sulfur cluster assembly enzyme b; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. | 0.577 |
ENSPMEP00000007622 | glrx5 | ENSPMEP00000007622 | ENSPMEP00000003429 | Iron-sulfur cluster assembly enzyme b; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | Glutaredoxin 5 homolog (S. cerevisiae). | 0.492 |
ENSPMEP00000007622 | isca1 | ENSPMEP00000007622 | ENSPMEP00000029884 | Iron-sulfur cluster assembly enzyme b; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | Iron-sulfur cluster assembly 1. | 0.920 |
ENSPMEP00000007622 | isca2 | ENSPMEP00000007622 | ENSPMEP00000027318 | Iron-sulfur cluster assembly enzyme b; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | Iron-sulfur cluster assembly 2. | 0.920 |
ENSPMEP00000025026 | ENSPMEP00000007622 | ENSPMEP00000025026 | ENSPMEP00000007622 | Frataxin. | Iron-sulfur cluster assembly enzyme b; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | 0.979 |
ENSPMEP00000025026 | LOC106904782 | ENSPMEP00000025026 | ENSPMEP00000020530 | Frataxin. | Uncharacterized protein. | 0.557 |
ENSPMEP00000025026 | LOC106918392 | ENSPMEP00000025026 | ENSPMEP00000023730 | Frataxin. | BolA family member 2; Belongs to the BolA/IbaG family. | 0.526 |
ENSPMEP00000025026 | LOC106918413 | ENSPMEP00000025026 | ENSPMEP00000002276 | Frataxin. | Uncharacterized protein. | 0.557 |
ENSPMEP00000025026 | LOC106928075 | ENSPMEP00000025026 | ENSPMEP00000005232 | Frataxin. | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). | 0.679 |
ENSPMEP00000025026 | LOC106930666 | ENSPMEP00000025026 | ENSPMEP00000013467 | Frataxin. | Ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1. | 0.528 |
ENSPMEP00000025026 | SDHB | ENSPMEP00000025026 | ENSPMEP00000001618 | Frataxin. | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). | 0.679 |
ENSPMEP00000025026 | UQCRFS1 | ENSPMEP00000025026 | ENSPMEP00000011807 | Frataxin. | Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. | 0.528 |
ENSPMEP00000025026 | ciapin1 | ENSPMEP00000025026 | ENSPMEP00000000869 | Frataxin. | Anamorsin; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electron [...] | 0.561 |