(26 nodes) Protein K48-linked deubiquitination network (Poecilia mexicana)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	usp7	Ubiquitin specific peptidase 7 (herpes virus-associated); Belongs to the peptidase C19 family. (1184 aa)
	yod1	YOD1 deubiquitinase. (300 aa)
	cskmt	Methyltranfer_dom domain-containing protein. (273 aa)
	mindy2	MINDY lysine 48 deubiquitinase 2. (608 aa)
	LOC106921659	OTU domain-containing protein. (227 aa)
	otud3	OTU deubiquitinase 3. (358 aa)
	usp37	Ubiquitin carboxyl-terminal hydrolase. (952 aa)
	ENSPMEP00000008218	Ubiquitinyl hydrolase 1. (244 aa)
	otud5	OTU deubiquitinase 5a. (551 aa)
	mindy4	Si:dkey-30h22.11. (611 aa)
	otud7b	OTU deubiquitinase 7B. (913 aa)
	OTUB2	OTU deubiquitinase, ubiquitin aldehyde binding 2. (227 aa)
	usp5	Ubiquitin carboxyl-terminal hydrolase. (829 aa)
	bap1	Ubiquitin carboxyl-terminal hydrolase. (727 aa)
	mindy3	MINDY lysine 48 deubiquitinase 3. (501 aa)
	otub1	Ubiquitin thioesterase. (266 aa)
	usp33	Ubiquitin carboxyl-terminal hydrolase. (914 aa)
	otud7a	OTU deubiquitinase 7A. (956 aa)
	usp8	Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. (1075 aa)
	tnfaip3	Tumor necrosis factor, alpha-induced protein 3. (824 aa)
	usp20	Ubiquitin carboxyl-terminal hydrolase. (936 aa)
	otud4	OTU domain-containing protein. (918 aa)
	mindy1	MINDY lysine 48 deubiquitinase 1. (589 aa)
	vcpip1	Valosin containing protein (p97)/p47 complex interacting protein 1. (1164 aa)
	ENSPMEP00000029501	Uncharacterized protein. (436 aa)
	ENSPMEP00000029786	MINDY lysine 48 deubiquitinase 2. (409 aa)

Your Current Organism:

Poecilia mexicana

NCBI taxonomy Id: 48701
Other names: shortfin molly

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPMEP00000029501	usp37	ENSPMEP00000029501	ENSPMEP00000008116	Uncharacterized protein.	Ubiquitin carboxyl-terminal hydrolase.	0.413
ENSPMEP00000029501	usp5	ENSPMEP00000029501	ENSPMEP00000014638	Uncharacterized protein.	Ubiquitin carboxyl-terminal hydrolase.	0.655
ENSPMEP00000029501	usp8	ENSPMEP00000029501	ENSPMEP00000024932	Uncharacterized protein.	Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family.	0.403
LOC106921659	usp37	ENSPMEP00000005048	ENSPMEP00000008116	OTU domain-containing protein.	Ubiquitin carboxyl-terminal hydrolase.	0.535
LOC106921659	usp7	ENSPMEP00000005048	ENSPMEP00000001792	OTU domain-containing protein.	Ubiquitin specific peptidase 7 (herpes virus-associated); Belongs to the peptidase C19 family.	0.415
LOC106921659	usp8	ENSPMEP00000005048	ENSPMEP00000024932	OTU domain-containing protein.	Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family.	0.770
OTUB2	usp37	ENSPMEP00000014187	ENSPMEP00000008116	OTU deubiquitinase, ubiquitin aldehyde binding 2.	Ubiquitin carboxyl-terminal hydrolase.	0.535
OTUB2	usp7	ENSPMEP00000014187	ENSPMEP00000001792	OTU deubiquitinase, ubiquitin aldehyde binding 2.	Ubiquitin specific peptidase 7 (herpes virus-associated); Belongs to the peptidase C19 family.	0.415
OTUB2	usp8	ENSPMEP00000014187	ENSPMEP00000024932	OTU deubiquitinase, ubiquitin aldehyde binding 2.	Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family.	0.770
bap1	usp5	ENSPMEP00000018488	ENSPMEP00000014638	Ubiquitin carboxyl-terminal hydrolase.	Ubiquitin carboxyl-terminal hydrolase.	0.455
cskmt	usp37	ENSPMEP00000002864	ENSPMEP00000008116	Methyltranfer_dom domain-containing protein.	Ubiquitin carboxyl-terminal hydrolase.	0.513
cskmt	usp8	ENSPMEP00000002864	ENSPMEP00000024932	Methyltranfer_dom domain-containing protein.	Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family.	0.513
otub1	usp37	ENSPMEP00000022805	ENSPMEP00000008116	Ubiquitin thioesterase.	Ubiquitin carboxyl-terminal hydrolase.	0.577
otub1	usp7	ENSPMEP00000022805	ENSPMEP00000001792	Ubiquitin thioesterase.	Ubiquitin specific peptidase 7 (herpes virus-associated); Belongs to the peptidase C19 family.	0.415
otub1	usp8	ENSPMEP00000022805	ENSPMEP00000024932	Ubiquitin thioesterase.	Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family.	0.836
otub1	yod1	ENSPMEP00000022805	ENSPMEP00000002112	Ubiquitin thioesterase.	YOD1 deubiquitinase.	0.521
otud3	otud4	ENSPMEP00000005194	ENSPMEP00000026311	OTU deubiquitinase 3.	OTU domain-containing protein.	0.463
otud3	otud7a	ENSPMEP00000005194	ENSPMEP00000024057	OTU deubiquitinase 3.	OTU deubiquitinase 7A.	0.410
otud3	otud7b	ENSPMEP00000005194	ENSPMEP00000011784	OTU deubiquitinase 3.	OTU deubiquitinase 7B.	0.410
otud4	otud3	ENSPMEP00000026311	ENSPMEP00000005194	OTU domain-containing protein.	OTU deubiquitinase 3.	0.463