59 items (Poecilia mexicana) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC106929649	C1q domain-containing protein. (618 aa)
	LOC106904616	Uncharacterized protein. (566 aa)
	prdx5	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (190 aa)
	LOC106907628	GLOBIN domain-containing protein; Belongs to the globin family. (144 aa)
	fancc	FA complementation group C. (578 aa)
	pxdn	Peroxidasin. (1571 aa)
	ENSPMEP00000020334	Eosinophil peroxidase. (397 aa)
	rfk	Riboflavin kinase. (169 aa)
	LOC106926553	Uncharacterized protein; Belongs to the complex I 75 kDa subunit family. (731 aa)
	LOC106906293	NADPH oxidase organizer 1b. (467 aa)
	ccn1	Cellular communication network factor 1. (376 aa)
	noxo1	NADPH oxidase organizer 1a. (516 aa)
	ncf2	Neutrophil cytosolic factor 2. (506 aa)
	LOC106921903	Peroxiredoxin 4. (261 aa)
	LOC106928169	Innate immunity activator b. (613 aa)
	sh3pxd2b	SH3 and PX domains 2B. (926 aa)
	gbf1	Golgi brefeldin A resistant guanine nucleotide exchange factor 1. (1865 aa)
	ncf1	Neutrophil cytosolic factor 1. (411 aa)
	PRDX2	Peroxiredoxin 2. (197 aa)
	NDUFS1	NADH:ubiquinone oxidoreductase core subunit S1; Belongs to the complex I 75 kDa subunit family. (739 aa)
	ENSPMEP00000004544	Platelet-derived growth factor beta polypeptide b; Belongs to the PDGF/VEGF growth factor family. (428 aa)
	LOC106919778	Platelet-derived growth factor beta polypeptide a; Belongs to the PDGF/VEGF growth factor family. (561 aa)
	ncf4	Neutrophil cytosolic factor 4. (350 aa)
	LOC106917018	SH3 and PX domains 2Aa. (1082 aa)
	bnip3	BCL2 interacting protein 3. (191 aa)
	ENSPMEP00000010375	Si:dkey-238f9.1. (156 aa)
	LOC106907191	NADH:ubiquinone oxidoreductase core subunit S1; Belongs to the complex I 75 kDa subunit family. (756 aa)
	nnt	Nicotinamide nucleotide transhydrogenase. (1087 aa)
	LOC106924098	Cytochrome b-245, alpha polypeptide. (197 aa)
	NDUFA13	NADH:ubiquinone oxidoreductase subunit A13. (144 aa)
	LOC106914125	Uncharacterized protein. (1095 aa)
	LOC106924766	Nicotinamide nucleotide transhydrogenase 2. (1030 aa)
	ndufs4	NADH:ubiquinone oxidoreductase subunit S4. (170 aa)
	ENSPMEP00000014332	Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. (128 aa)
	nox4	FAD-binding FR-type domain-containing protein. (560 aa)
	TPO	Thyroid peroxidase. (832 aa)
	ENSPMEP00000034487	Uncharacterized protein. (119 aa)
	ccn2	Cellular communication network factor 2a. (346 aa)
	LOC106914095	Superoxide dismutase [Cu-Zn]-like. (154 aa)
	LOC106919351	Dual oxidase 2. (323 aa)
	LOC106919349	Dual oxidase. (1497 aa)
	LOC106931359	Innate immunity activator a. (567 aa)
	LOC106925485	Myeloid-specific peroxidase. (826 aa)
	sod2	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (225 aa)
	spast	Spastin; Belongs to the AAA ATPase family. (479 aa)
	ccs	Copper chaperone for superoxide dismutase. (307 aa)
	ENSPMEP00000027716	TAFA chemokine like family member 4b. (176 aa)
	cat	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (527 aa)
	nrros	Negative regulator of reactive oxygen species. (685 aa)
	LOC106912535	Zgc:73226. (182 aa)
	lrrk2	Leucine-rich repeat kinase 2. (2252 aa)
	prdx3	Peroxiredoxin 3. (248 aa)
	ndufs3	NADH:ubiquinone oxidoreductase core subunit S3; Belongs to the complex I 30 kDa subunit family. (260 aa)
	nox5	NADPH oxidase, EF-hand calcium binding domain 5. (700 aa)
	SOD1	Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (154 aa)
	bcl2	BCL2 apoptosis regulator b. (229 aa)
	sod3	Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (215 aa)
	LOC106919016	Peroxiredoxin 1. (199 aa)
	LOC106904491	AlaDh_PNT_C domain-containing protein. (793 aa)

Your Current Organism:

Poecilia mexicana

NCBI taxonomy Id: 48701
Other names: shortfin molly

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPMEP00000014332	LOC106907628	ENSPMEP00000014332	ENSPMEP00000021059	Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family.	GLOBIN domain-containing protein; Belongs to the globin family.	0.696
ENSPMEP00000014332	cat	ENSPMEP00000014332	ENSPMEP00000027352	Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family.	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	0.487
ENSPMEP00000014332	rfk	ENSPMEP00000014332	ENSPMEP00000019799	Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family.	Riboflavin kinase.	0.823
ENSPMEP00000014332	sod2	ENSPMEP00000014332	ENSPMEP00000028422	Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family.	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	0.664
ENSPMEP00000020334	LOC106914095	ENSPMEP00000020334	ENSPMEP00000031047	Eosinophil peroxidase.	Superoxide dismutase [Cu-Zn]-like.	0.420
ENSPMEP00000020334	LOC106919016	ENSPMEP00000020334	ENSPMEP00000023065	Eosinophil peroxidase.	Peroxiredoxin 1.	0.440
ENSPMEP00000020334	LOC106919351	ENSPMEP00000020334	ENSPMEP00000030698	Eosinophil peroxidase.	Dual oxidase 2.	0.456
ENSPMEP00000020334	LOC106924098	ENSPMEP00000020334	ENSPMEP00000011759	Eosinophil peroxidase.	Cytochrome b-245, alpha polypeptide.	0.597
ENSPMEP00000020334	LOC106925485	ENSPMEP00000020334	ENSPMEP00000028727	Eosinophil peroxidase.	Myeloid-specific peroxidase.	0.572
ENSPMEP00000020334	LOC106929649	ENSPMEP00000020334	ENSPMEP00000021881	Eosinophil peroxidase.	C1q domain-containing protein.	0.588
ENSPMEP00000020334	SOD1	ENSPMEP00000020334	ENSPMEP00000024363	Eosinophil peroxidase.	Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family.	0.420
ENSPMEP00000020334	TPO	ENSPMEP00000020334	ENSPMEP00000016489	Eosinophil peroxidase.	Thyroid peroxidase.	0.902
ENSPMEP00000020334	cat	ENSPMEP00000020334	ENSPMEP00000027352	Eosinophil peroxidase.	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	0.590
ENSPMEP00000020334	nox5	ENSPMEP00000020334	ENSPMEP00000025171	Eosinophil peroxidase.	NADPH oxidase, EF-hand calcium binding domain 5.	0.617
ENSPMEP00000020334	sod3	ENSPMEP00000020334	ENSPMEP00000016588	Eosinophil peroxidase.	Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family.	0.420
LOC106904491	LOC106914095	ENSPMEP00000022608	ENSPMEP00000031047	AlaDh_PNT_C domain-containing protein.	Superoxide dismutase [Cu-Zn]-like.	0.512
LOC106904491	SOD1	ENSPMEP00000022608	ENSPMEP00000024363	AlaDh_PNT_C domain-containing protein.	Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family.	0.512
LOC106904491	cat	ENSPMEP00000022608	ENSPMEP00000027352	AlaDh_PNT_C domain-containing protein.	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	0.733
LOC106904491	nnt	ENSPMEP00000022608	ENSPMEP00000011459	AlaDh_PNT_C domain-containing protein.	Nicotinamide nucleotide transhydrogenase.	0.898
LOC106904491	sod2	ENSPMEP00000022608	ENSPMEP00000028422	AlaDh_PNT_C domain-containing protein.	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	0.727