(104 nodes) Protein-tyrosine phosphatase, active site network (Poecilia mexicana)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC106907757	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (184 aa)
	PTPN20	Protein tyrosine phosphatase non-receptor type 20. (221 aa)
	ptprg	Carbonic anhydrase XVI b. (1408 aa)
	LOC106914311	Uncharacterized protein; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (195 aa)
	odf3b	Zgc:77752. (446 aa)
	ptpn11	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (596 aa)
	ptpdc1	Protein tyrosine phosphatase domain containing 1a. (690 aa)
	ptprq	Protein tyrosine phosphatase receptor type Q. (2244 aa)
	LOC106932994	Protein tyrosine phosphatase non-receptor type 11b. (584 aa)
	dusp1	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (376 aa)
	DUSP26	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (200 aa)
	ENSPMEP00000000823	Uncharacterized protein. (327 aa)
	ENSPMEP00000000768	Uncharacterized protein. (312 aa)
	ptpn12	Uncharacterized protein. (795 aa)
	LOC106922645	Si:dkey-175m17.7. (879 aa)
	mtmr2	Myotubularin related protein 2. (683 aa)
	LOC106916778	Tyrosine-protein phosphatase non-receptor type. (431 aa)
	ENSPMEP00000021557	Dual specificity phosphatase 3b. (118 aa)
	ENSPMEP00000021964	Uncharacterized protein; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (187 aa)
	cdkn3	Cyclin-dependent kinase inhibitor 3; May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues. (209 aa)
	LOC106908319	Uncharacterized protein. (485 aa)
	LOC106904485	Protein tyrosine phosphatase receptor type Sa. (1662 aa)
	LOC106915168	Receptor-type tyrosine-protein phosphatase. (700 aa)
	mtmr7	Myotubularin related protein 7a. (651 aa)
	dusp12	Dual specificity phosphatase 12. (303 aa)
	LOC106910569	Protein tyrosine phosphatase non-receptor type 9a. (494 aa)
	dusp16	Dual specificity phosphatase 16. (631 aa)
	dusp5	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (376 aa)
	LOC106921931	Dual specificity phosphatase 2. (315 aa)
	ssh3	Si:ch211-203d1.3. (632 aa)
	LOC106904667	Slingshot protein phosphatase 1b. (679 aa)
	LOC106928785	Protein tyrosine phosphatase receptor type Ua. (1410 aa)
	ptprk	Protein tyrosine phosphatase receptor type K. (1453 aa)
	ptpn21	Protein tyrosine phosphatase non-receptor type 21. (1196 aa)
	dusp19	Uncharacterized protein. (203 aa)
	LOC106919556	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (212 aa)
	ENSPMEP00000027280	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (184 aa)
	MTMR4	Myotubularin related protein 4. (1159 aa)
	ptpn9	Protein tyrosine phosphatase non-receptor type 9a. (568 aa)
	ptpro	Protein tyrosine phosphatase receptor type O. (377 aa)
	PTPN14	Protein tyrosine phosphatase non-receptor type 14. (1253 aa)
	LOC106906457	Protein tyrosine phosphatase non-receptor type 9b. (749 aa)
	LOC106910023	Protein tyrosine phosphatase receptor type Z1b. (1431 aa)
	ENSPMEP00000030993	Uncharacterized protein. (233 aa)
	LOC106918703	Uncharacterized protein. (1490 aa)
	ptpn23	Protein tyrosine phosphatase, non-receptor type 23, a. (1879 aa)
	LOC106922646	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (367 aa)
	LOC106920449	Dual specificity phosphatase 22a. (224 aa)
	LOC106907756	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (226 aa)
	LOC106918628	Protein tyrosine phosphatase receptor type Sa. (1491 aa)
	mtmr3	Myotubularin related protein 3. (1222 aa)
	LOC106904808	Tyrosine-protein phosphatase non-receptor type. (404 aa)
	mtmr6	Myotubularin related protein 6. (657 aa)
	LOC106906222	Uncharacterized protein. (408 aa)
	LOC106917253	Myotubularin related protein 1a. (647 aa)
	dusp23	Dual specificity phosphatase 23a. (151 aa)
	LOC106933821	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (195 aa)
	mtm1	Myotubularin 1. (620 aa)
	LOC106923832	Protein tyrosine phosphatase domain containing 1b. (670 aa)
	LOC106933842	Slingshot protein phosphatase 2a. (1247 aa)
	PTPRB-2	Protein tyrosine phosphatase receptor type B. (1457 aa)
	ENSPMEP00000019243	Si:ch1073-184j22.2; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (170 aa)
	pten	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (446 aa)
	ssh1	Slingshot protein phosphatase 1a. (1030 aa)
	PTPRB	Protein tyrosine phosphatase receptor type B. (2618 aa)
	ENSPMEP00000017818	Uncharacterized protein. (625 aa)
	cdc14a	Cell division cycle 14Ab. (591 aa)
	ENSPMEP00000017416	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (225 aa)
	ENSPMEP00000017345	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (192 aa)
	ptprf	Protein tyrosine phosphatase receptor type Fb. (1913 aa)
	LOC106907754	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (213 aa)
	LOC106919989	Protein tyrosine phosphatase receptor type Ub. (1442 aa)
	dusp10	Dual specificity phosphatase 10. (472 aa)
	ptpra	Receptor-type tyrosine-protein phosphatase alpha. (789 aa)
	LOC106909380	Uncharacterized protein. (406 aa)
	LOC106929895	Protein tyrosine phosphatase non-receptor type 3. (813 aa)
	mtmr14	Myotubularin related protein 14. (657 aa)
	ptprc	Uncharacterized protein. (726 aa)
	LOC106916149	TYR_PHOSPHATASE_2 domain-containing protein. (315 aa)
	ENSPMEP00000012718	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (193 aa)
	LOC106931871	Dual specificity phosphatase 11 (RNA/RNP complex 1-interacting). (362 aa)
	LOC106914115	Transmembrane phosphatase with tensin homology. (512 aa)
	dusp8	Dual specificity phosphatase 8a. (680 aa)
	ENSPMEP00000012202	Protein tyrosine phosphatase non-receptor type 5. (370 aa)
	LOC106916782	Uncharacterized protein. (1450 aa)
	LOC106910736	Slingshot protein phosphatase 2b. (1168 aa)
	LOC106905811	Myotubularin related protein 7b. (577 aa)
	LOC106934271	Uncharacterized protein. (743 aa)
	LOC106908806	Uncharacterized protein. (346 aa)
	rngtt	Polynucleotide 5'-triphosphatase; Bifunctional mRNA-capping enzyme exhibiting RNA 5'- triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5'-diphosphate terminus. (602 aa)
	ptpn4	Protein tyrosine phosphatase non-receptor type 4a. (1027 aa)
	ptpre	Receptor-type tyrosine-protein phosphatase. (636 aa)
	LOC106919542	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (207 aa)
	LOC106919554	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (188 aa)
	DUSP13	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (187 aa)
	ENSPMEP00000009104	Uncharacterized protein. (233 aa)
	epm2a	EPM2A glucan phosphatase, laforin. (316 aa)
	LOC106920242	Uncharacterized protein. (553 aa)
	LOC106919585	Uncharacterized protein. (705 aa)
	LOC106908005	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (412 aa)
	LOC106932081	Uncharacterized protein. (394 aa)
	PTPRD	Protein tyrosine phosphatase receptor type D. (1388 aa)
	dusp14	Dual specificity phosphatase 14; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (212 aa)
	LOC106905232	Protein tyrosine phosphatase non-receptor type 6. (583 aa)

Your Current Organism:

Poecilia mexicana

NCBI taxonomy Id: 48701
Other names: shortfin molly

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DUSP13	ENSPMEP00000012202	ENSPMEP00000009627	ENSPMEP00000012202	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Protein tyrosine phosphatase non-receptor type 5.	0.539
DUSP13	LOC106909380	ENSPMEP00000009627	ENSPMEP00000014763	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Uncharacterized protein.	0.548
DUSP13	PTPN20	ENSPMEP00000009627	ENSPMEP00000004534	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Protein tyrosine phosphatase non-receptor type 20.	0.451
DUSP13	ptprq	ENSPMEP00000009627	ENSPMEP00000002330	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Protein tyrosine phosphatase receptor type Q.	0.519
DUSP26	ENSPMEP00000012202	ENSPMEP00000000899	ENSPMEP00000012202	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Protein tyrosine phosphatase non-receptor type 5.	0.544
DUSP26	LOC106909380	ENSPMEP00000000899	ENSPMEP00000014763	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Uncharacterized protein.	0.548
DUSP26	PTPN20	ENSPMEP00000000899	ENSPMEP00000004534	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Protein tyrosine phosphatase non-receptor type 20.	0.451
DUSP26	ptprq	ENSPMEP00000000899	ENSPMEP00000002330	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Protein tyrosine phosphatase receptor type Q.	0.519
ENSPMEP00000000768	PTPRB	ENSPMEP00000000768	ENSPMEP00000017995	Uncharacterized protein.	Protein tyrosine phosphatase receptor type B.	0.899
ENSPMEP00000000823	LOC106905232	ENSPMEP00000000823	ENSPMEP00000004820	Uncharacterized protein.	Protein tyrosine phosphatase non-receptor type 6.	0.602
ENSPMEP00000000823	LOC106932994	ENSPMEP00000000823	ENSPMEP00000001892	Uncharacterized protein.	Protein tyrosine phosphatase non-receptor type 11b.	0.602
ENSPMEP00000000823	ptpn11	ENSPMEP00000000823	ENSPMEP00000003082	Uncharacterized protein.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.602
ENSPMEP00000009104	LOC106905232	ENSPMEP00000009104	ENSPMEP00000004820	Uncharacterized protein.	Protein tyrosine phosphatase non-receptor type 6.	0.602
ENSPMEP00000009104	LOC106932994	ENSPMEP00000009104	ENSPMEP00000001892	Uncharacterized protein.	Protein tyrosine phosphatase non-receptor type 11b.	0.602
ENSPMEP00000009104	ptpn11	ENSPMEP00000009104	ENSPMEP00000003082	Uncharacterized protein.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.602
ENSPMEP00000012202	DUSP13	ENSPMEP00000012202	ENSPMEP00000009627	Protein tyrosine phosphatase non-receptor type 5.	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.539
ENSPMEP00000012202	DUSP26	ENSPMEP00000012202	ENSPMEP00000000899	Protein tyrosine phosphatase non-receptor type 5.	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.544
ENSPMEP00000012202	ENSPMEP00000012718	ENSPMEP00000012202	ENSPMEP00000012718	Protein tyrosine phosphatase non-receptor type 5.	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.898
ENSPMEP00000012202	ENSPMEP00000017345	ENSPMEP00000012202	ENSPMEP00000017345	Protein tyrosine phosphatase non-receptor type 5.	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.539
ENSPMEP00000012202	ENSPMEP00000017416	ENSPMEP00000012202	ENSPMEP00000017416	Protein tyrosine phosphatase non-receptor type 5.	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.539