117 items (Poecilia mexicana) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC106912598	Zgc:113162. (253 aa)
	sema6b	Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6Bb; Belongs to the semaphorin family. (870 aa)
	sema3e	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E; Belongs to the semaphorin family. (685 aa)
	ENSPMEP00000000668	Plexin_cytopl domain-containing protein. (161 aa)
	LOC106932286	Dihydropyrimidinase like 3. (310 aa)
	LOC106904565	Dihydropyrimidinase like 5a. (564 aa)
	LOC106908941	Plexin C1. (594 aa)
	LOC106905356	Non-specific serine/threonine protein kinase. (507 aa)
	LOC106919088	Rho GTPase activating protein 35b. (1529 aa)
	LOC106906671	Tyrosine-protein kinase. (537 aa)
	plxnb1	Plexin b1b. (2193 aa)
	LOC106932922	Sema domain-containing protein; Belongs to the semaphorin family. (1171 aa)
	ENSPMEP00000003807	Plexin_cytopl domain-containing protein. (47 aa)
	LOC106931696	Uncharacterized protein. (193 aa)
	LOC106920493	Plexin A2. (1822 aa)
	dpysl5	Dihydropyrimidinase like 5b. (567 aa)
	gsk3b	Glycogen synthase kinase 3 beta, genome duplicate a; Belongs to the protein kinase superfamily. (421 aa)
	LOC106910538	Rho-associated, coiled-coil containing protein kinase 2a; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1329 aa)
	farp2	FERM, RhoGEF and pleckstrin domain protein 2. (1055 aa)
	LOC106925046	Zgc:103559. (447 aa)
	rock1	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1380 aa)
	LOC106912208	Plexin A3. (1138 aa)
	LOC106917766	Si:ch211-129c21.1; Belongs to the semaphorin family. (804 aa)
	ENSPMEP00000006715	Uncharacterized protein. (134 aa)
	ENSPMEP00000006731	Uncharacterized protein. (260 aa)
	sema6a	Semaphorin 6A; Belongs to the semaphorin family. (1004 aa)
	LOC106916349	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1. (705 aa)
	arhgef12	Rho guanine nucleotide exchange factor (GEF) 12a. (1438 aa)
	SEMA4D	Uncharacterized protein; Belongs to the semaphorin family. (883 aa)
	LOC106903887	Uncharacterized protein. (193 aa)
	LOC106926316	PIPK domain-containing protein. (789 aa)
	LOC106905060	Uncharacterized protein; Belongs to the semaphorin family. (770 aa)
	LOC106911171	RAS related. (197 aa)
	cfl2	Cofilin 2 (muscle); Belongs to the actin-binding proteins ADF family. (168 aa)
	LOC106931987	Polymeric immunoglobulin receptor. (311 aa)
	LOC106920794	Talin 2a. (2532 aa)
	ENSPMEP00000009484	Uncharacterized protein. (84 aa)
	LOC106931417	Uncharacterized protein; Belongs to the semaphorin family. (838 aa)
	ENSPMEP00000010756	Sema domain-containing protein. (442 aa)
	nrp1	Neuropilin; Belongs to the neuropilin family. (919 aa)
	LOC106920154	Uncharacterized protein; Belongs to the semaphorin family. (610 aa)
	PAK3	Non-specific serine/threonine protein kinase. (575 aa)
	ENSPMEP00000011819	Plexin_cytopl domain-containing protein. (54 aa)
	ENSPMEP00000011832	Uncharacterized protein. (383 aa)
	limk1	LIM domain kinase 1b. (753 aa)
	sema4b	Sema domain-containing protein; Belongs to the semaphorin family. (834 aa)
	sema6d	Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D, like; Belongs to the semaphorin family. (1109 aa)
	met	MET proto-oncogene, receptor tyrosine kinase. (1418 aa)
	RND1	Rho family GTPase 1. (232 aa)
	ptprc	Uncharacterized protein. (726 aa)
	ENSPMEP00000013461	Uncharacterized protein. (156 aa)
	ENSPMEP00000014323	Protein kinase domain-containing protein. (77 aa)
	pak2	Non-specific serine/threonine protein kinase. (525 aa)
	cdk5	Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
	LOC106918068	Uncharacterized protein. (193 aa)
	LOC106925151	Uncharacterized protein. (193 aa)
	erbb2	Receptor protein-tyrosine kinase. (1286 aa)
	hsp90ab1	Heat shock protein 90, alpha (cytosolic), class B member 1. (723 aa)
	ENSPMEP00000016624	Uncharacterized protein. (411 aa)
	ENSPMEP00000016745	Dihydropyrimidinase like 4. (249 aa)
	LOC106915444	Plexin b1a. (2162 aa)
	LOC106904907	Glycogen synthase kinase 3 alpha b; Belongs to the protein kinase superfamily. (440 aa)
	LOC106918632	Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6Ba; Belongs to the semaphorin family. (849 aa)
	ENSPMEP00000018443	Sema domain-containing protein. (443 aa)
	limk2	LIM domain kinase 2. (684 aa)
	LOC106926573	Uncharacterized protein. (202 aa)
	tyrobp	Uncharacterized protein. (108 aa)
	LOC106912597	Dual specificity testis-specific protein kinase 1-like. (253 aa)
	LOC106907692	Plexin_cytopl domain-containing protein. (74 aa)
	LOC106931768	Ras homolog family member Ca. (193 aa)
	pak1	Non-specific serine/threonine protein kinase. (563 aa)
	sema7a	Semaphorin 7A; Belongs to the semaphorin family. (653 aa)
	LOC106931724	Dihydropyrimidinase like 2b. (650 aa)
	sema3a	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ab; Belongs to the semaphorin family. (801 aa)
	LOC106905410	Uncharacterized protein. (103 aa)
	PLXNA2	Plexin A2. (1882 aa)
	cdk5r2	Cyclin-dependent kinase 5, regulatory subunit 2b (p39). (290 aa)
	LOC106909865	Uncharacterized protein. (230 aa)
	ENSPMEP00000022795	Sema domain-containing protein. (393 aa)
	ENSPMEP00000024054	Uncharacterized protein. (128 aa)
	ROCK2	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1401 aa)
	LOC106915081	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Aa; Belongs to the semaphorin family. (853 aa)
	LOC106920376	Si:ch211-113g11.6; Belongs to the semaphorin family. (471 aa)
	cdk5r1	Cyclin-dependent kinase 5 activator. (302 aa)
	LOC106917759	Phosphatidylinositol-4-phosphate 5-kinase, type I, gamma a. (695 aa)
	ENSPMEP00000025333	Sema domain-containing protein. (598 aa)
	LOC106903969	Uncharacterized protein. (1160 aa)
	LOC106916348	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2. (733 aa)
	plxna1	Sema domain-containing protein. (1948 aa)
	LOC106920294	Cofilin 1; Belongs to the actin-binding proteins ADF family. (176 aa)
	LOC106914967	Rho family GTPase 1b. (232 aa)
	tln2	Talin 2b. (2410 aa)
	dstn	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (159 aa)
	pkhd1l1	Si:ch211-244a23.1. (2931 aa)
	ENSPMEP00000028241	Uncharacterized protein; Belongs to the protein kinase superfamily. (425 aa)
	arhgap35	Uncharacterized protein. (1551 aa)
	LOC106928660	Collapsin response mediator protein 1. (544 aa)
	LOC106927273	LIM domain kinase 1a. (703 aa)
	LOC106929956	Talin 1. (2545 aa)
	LOC106911984	Sema domain-containing protein; Belongs to the semaphorin family. (638 aa)
	ENSPMEP00000029506	Uncharacterized protein. (393 aa)
	LOC106911976	PA14 domain-containing protein. (648 aa)
	LOC106922715	Sema domain-containing protein. (1783 aa)
	LOC106931821	Cyclin-dependent kinase 5 activator. (334 aa)
	plxnb2	Plexin b2b. (1848 aa)
	LOC106926592	Glycogen synthase kinase 3 alpha a; Belongs to the protein kinase superfamily. (409 aa)
	LOC106929823	Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6E; Belongs to the semaphorin family. (1086 aa)
	LOC106918638	Semaphorin 4e; Belongs to the semaphorin family. (753 aa)
	sema3g	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3bl; Belongs to the semaphorin family. (784 aa)
	sema3b	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B; Belongs to the semaphorin family. (809 aa)
	DPYSL2	Dihydropyrimidinase like 2. (582 aa)
	LOC106924514	Dihydropyrimidinase like 3. (569 aa)
	LOC106909963	Sema domain-containing protein; Belongs to the semaphorin family. (772 aa)
	LOC106903328	Tyrosine-protein kinase. (589 aa)
	tlnrd1	Talin rod domain containing 1. (354 aa)
	plxna4	Plexin A4. (1375 aa)
	LOC106923559	Cyclin-dependent kinase 5 activator. (323 aa)

Your Current Organism:

Poecilia mexicana

NCBI taxonomy Id: 48701
Other names: shortfin molly

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DPYSL2	ENSPMEP00000024054	ENSPMEP00000033043	ENSPMEP00000024054	Dihydropyrimidinase like 2.	Uncharacterized protein.	0.565
DPYSL2	LOC106904907	ENSPMEP00000033043	ENSPMEP00000017881	Dihydropyrimidinase like 2.	Glycogen synthase kinase 3 alpha b; Belongs to the protein kinase superfamily.	0.565
DPYSL2	LOC106926592	ENSPMEP00000033043	ENSPMEP00000031453	Dihydropyrimidinase like 2.	Glycogen synthase kinase 3 alpha a; Belongs to the protein kinase superfamily.	0.565
DPYSL2	cdk5	ENSPMEP00000033043	ENSPMEP00000014717	Dihydropyrimidinase like 2.	Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily.	0.631
DPYSL2	gsk3b	ENSPMEP00000033043	ENSPMEP00000004812	Dihydropyrimidinase like 2.	Glycogen synthase kinase 3 beta, genome duplicate a; Belongs to the protein kinase superfamily.	0.565
DPYSL2	met	ENSPMEP00000033043	ENSPMEP00000013002	Dihydropyrimidinase like 2.	MET proto-oncogene, receptor tyrosine kinase.	0.580
DPYSL2	nrp1	ENSPMEP00000033043	ENSPMEP00000011003	Dihydropyrimidinase like 2.	Neuropilin; Belongs to the neuropilin family.	0.443
ENSPMEP00000000668	ENSPMEP00000010756	ENSPMEP00000000668	ENSPMEP00000010756	Plexin_cytopl domain-containing protein.	Sema domain-containing protein.	0.655
ENSPMEP00000000668	ENSPMEP00000014323	ENSPMEP00000000668	ENSPMEP00000014323	Plexin_cytopl domain-containing protein.	Protein kinase domain-containing protein.	0.482
ENSPMEP00000000668	ENSPMEP00000022795	ENSPMEP00000000668	ENSPMEP00000022795	Plexin_cytopl domain-containing protein.	Sema domain-containing protein.	0.729
ENSPMEP00000000668	ENSPMEP00000025333	ENSPMEP00000000668	ENSPMEP00000025333	Plexin_cytopl domain-containing protein.	Sema domain-containing protein.	0.694
ENSPMEP00000000668	LOC106903328	ENSPMEP00000000668	ENSPMEP00000034110	Plexin_cytopl domain-containing protein.	Tyrosine-protein kinase.	0.482
ENSPMEP00000000668	LOC106903887	ENSPMEP00000000668	ENSPMEP00000008213	Plexin_cytopl domain-containing protein.	Uncharacterized protein.	0.487
ENSPMEP00000000668	LOC106903969	ENSPMEP00000000668	ENSPMEP00000025422	Plexin_cytopl domain-containing protein.	Uncharacterized protein.	0.546
ENSPMEP00000000668	LOC106905060	ENSPMEP00000000668	ENSPMEP00000008519	Plexin_cytopl domain-containing protein.	Uncharacterized protein; Belongs to the semaphorin family.	0.586
ENSPMEP00000000668	LOC106905410	ENSPMEP00000000668	ENSPMEP00000021866	Plexin_cytopl domain-containing protein.	Uncharacterized protein.	0.487
ENSPMEP00000000668	LOC106906671	ENSPMEP00000000668	ENSPMEP00000002672	Plexin_cytopl domain-containing protein.	Tyrosine-protein kinase.	0.482
ENSPMEP00000000668	LOC106909963	ENSPMEP00000000668	ENSPMEP00000033777	Plexin_cytopl domain-containing protein.	Sema domain-containing protein; Belongs to the semaphorin family.	0.586
ENSPMEP00000000668	LOC106911171	ENSPMEP00000000668	ENSPMEP00000008651	Plexin_cytopl domain-containing protein.	RAS related.	0.536
ENSPMEP00000000668	LOC106911984	ENSPMEP00000000668	ENSPMEP00000029476	Plexin_cytopl domain-containing protein.	Sema domain-containing protein; Belongs to the semaphorin family.	0.626