STRINGSTRING
pold2 pold2 cul4b cul4b gtf2h5 gtf2h5 LOC106925417 LOC106925417 LOC106931831 LOC106931831 LOC106926029 LOC106926029 ENSPMEP00000030828 ENSPMEP00000030828 wbp1 wbp1 ENSPMEP00000031523 ENSPMEP00000031523 polk polk ENSPMEP00000032240 ENSPMEP00000032240 POLE POLE cdk7 cdk7 LOC106923920 LOC106923920 LOC106911701 LOC106911701 rfc3 rfc3 rpa3 rpa3 pole3 pole3 polr2c polr2c LOC106909031 LOC106909031 polr2a polr2a lig3 lig3 parp3 parp3 usp7 usp7 RCBTB1 RCBTB1 LOC106904547 LOC106904547 cops2 cops2 COPS6 COPS6 LOC106914335 LOC106914335 cops7a cops7a polr2d polr2d ercc6 ercc6 LOC106911418 LOC106911418 tcea1 tcea1 ino80d ino80d actr5 actr5 rnf111 rnf111 LOC106905387 LOC106905387 POLR2E POLR2E pcna pcna kxd1 kxd1 cops4 cops4 prpf19 prpf19 polr2g polr2g LOC106914402 LOC106914402 ENSPMEP00000008453 ENSPMEP00000008453 TCEANC TCEANC actr8 actr8 sumo1 sumo1 ddb1 ddb1 LOC106911565 LOC106911565 nrde2 nrde2 LOC106909638 LOC106909638 xab2 xab2 atad5 atad5 ino80b ino80b polr2b polr2b rfc2 rfc2 ENSPMEP00000010995 ENSPMEP00000010995 rpa2 rpa2 cul4a cul4a ino80c ino80c lig1 lig1 ppp1r42 ppp1r42 parp1 parp1 pold4 pold4 rfc5 rfc5 wdr76 wdr76 pole4 pole4 uba52 uba52 LOC106919377 LOC106919377 rpap3 rpap3 usp40 usp40 rad23a rad23a ercc3 ercc3 ENSPMEP00000014498 ENSPMEP00000014498 LOC106923389 LOC106923389 LOC106928565 LOC106928565 LOC106926030 LOC106926030 tfpt tfpt rbx1 rbx1 gps1 gps1 ube2n ube2n polr2f polr2f pold1 pold1 LOC106934012 LOC106934012 ppie ppie cops3 cops3 LOC106908123 LOC106908123 LOC106915420 LOC106915420 polr2j polr2j bivm bivm ddb2 ddb2 kctd2 kctd2 ino80 ino80 LOC106905490 LOC106905490 ercc4 ercc4 LOC106926528 LOC106926528 gtf2h3 gtf2h3 pold3 pold3 parp2 parp2 ZNF830 ZNF830 cops8 cops8 ercc1 ercc1 LOC106929849 LOC106929849 sumo2 sumo2 polr2l polr2l rps27a rps27a LOC106924789 LOC106924789 mnat1 mnat1 gtf2h4 gtf2h4 LOC106924837 LOC106924837 cops5 cops5 LOC106910889 LOC106910889 tceanc2 tceanc2 actb actb LOC106910274 LOC106910274 mcrs1 mcrs1 LOC106926296 LOC106926296 xrcc1 xrcc1 LOC106933455 LOC106933455 ENSPMEP00000026342 ENSPMEP00000026342 pole2 pole2 LOC106920276 LOC106920276 LOC106918268 LOC106918268 chd1l chd1l ercc8 ercc8 xpc xpc rfc1 rfc1 ENSPMEP00000024553 ENSPMEP00000024553 polr2i polr2i polr2h polr2h ENSPMEP00000023683 ENSPMEP00000023683 ino80e ino80e LOC106916471 LOC106916471 aqr aqr LOC106906886 LOC106906886 ccnh ccnh LOC106906894 LOC106906894 meiob meiob ercc2 ercc2 ENSPMEP00000021685 ENSPMEP00000021685 LOC106909028 LOC106909028 rfc4 rfc4 nfrkb nfrkb YY1 YY1 ruvbl1 ruvbl1 ube2v2 ube2v2 ube2i ube2i polr2k polr2k LOC106906255 LOC106906255 xpa xpa ercc5 ercc5 gtf2h1 gtf2h1
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
pold2Polymerase (DNA directed), delta 2, regulatory subunit. (468 aa)
cul4bCullin 4B; Belongs to the cullin family. (868 aa)
gtf2h5General transcription factor IIH, polypeptide 5. (71 aa)
LOC106925417Small ubiquitin-related modifier. (94 aa)
LOC106931831Protein inhibitor of activated STAT, 1b. (656 aa)
LOC106926029Uncharacterized protein. (177 aa)
ENSPMEP00000030828Ubiquitin-like domain-containing protein. (112 aa)
wbp1Uncharacterized protein. (483 aa)
ENSPMEP00000031523Transcription elongation factor A (SII), 3. (315 aa)
polkPolymerase (DNA directed) kappa. (898 aa)
ENSPMEP00000032240DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (364 aa)
POLEDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (1123 aa)
cdk7Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (360 aa)
LOC106923920Small ubiquitin-related modifier. (94 aa)
LOC106911701General transcription factor IIH, polypeptide 2. (169 aa)
rfc3Replication factor C (activator 1) 3. (376 aa)
rpa3Replication protein A3. (122 aa)
pole3Polymerase (DNA directed), epsilon 3 (p17 subunit). (150 aa)
polr2cPolymerase (RNA) II (DNA directed) polypeptide C. (275 aa)
LOC106909031Uncharacterized protein. (121 aa)
polr2aDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1907 aa)
lig3DNA ligase. (998 aa)
parp3Poly [ADP-ribose] polymerase. (522 aa)
usp7Ubiquitin specific peptidase 7 (herpes virus-associated); Belongs to the peptidase C19 family. (1184 aa)
RCBTB1RCC1 and BTB domain containing protein 1. (554 aa)
LOC106904547RAD23 homolog B, nucleotide excision repair protein. (392 aa)
cops2COP9 signalosome subunit 2. (443 aa)
COPS6COP9 signalosome subunit 6. (316 aa)
LOC106914335Ubiquitinyl hydrolase 1. (783 aa)
cops7aCOP9 constitutive photomorphogenic homolog subunit 7A. (269 aa)
polr2dPolymerase (RNA) II (DNA directed) polypeptide D. (144 aa)
ercc6Excision repair cross-complementation group 6. (1446 aa)
LOC106911418Uncharacterized protein; Belongs to the actin family. (142 aa)
tcea1Transcription elongation factor A (SII), 1. (311 aa)
ino80dINO80 complex subunit Da. (1007 aa)
actr5Actin related protein 5; Belongs to the actin family. (624 aa)
rnf111Ring finger protein 111. (1021 aa)
LOC106905387Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1. (531 aa)
POLR2ERNA polymerase II subunit E. (210 aa)
pcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (282 aa)
kxd1KxDL motif containing 1. (186 aa)
cops4COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis). (406 aa)
prpf19Pre-mRNA processing factor 19. (505 aa)
polr2gPolymerase (RNA) II (DNA directed) polypeptide G-like. (172 aa)
LOC106914402Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2. (527 aa)
ENSPMEP00000008453Uncharacterized protein. (154 aa)
TCEANCTranscription elongation factor A N-terminal and central domain containing. (321 aa)
actr8Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily. (644 aa)
sumo1Small ubiquitin-related modifier. (111 aa)
ddb1Damage-specific DNA binding protein 1. (1139 aa)
LOC106911565PHD finger protein 3. (1653 aa)
nrde2NRDE-2, necessary for RNA interference, domain containing. (1205 aa)
LOC106909638High mobility group nucleosome binding domain 6. (97 aa)
xab2XPA binding protein 2. (849 aa)
atad5AAA domain-containing protein. (825 aa)
ino80bINO80 complex subunit B. (339 aa)
polr2bDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
rfc2Replication factor C (activator 1) 2. (357 aa)
ENSPMEP00000010995Uncharacterized protein. (230 aa)
rpa2Replication protein A2. (278 aa)
cul4aCullin 4A; Belongs to the cullin family. (646 aa)
ino80cINO80 complex subunit C. (216 aa)
lig1DNA ligase. (1002 aa)
ppp1r42Protein phosphatase 1, regulatory subunit 42. (291 aa)
parp1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1015 aa)
pold4Si:dkey-28b4.7. (108 aa)
rfc5Replication factor C (activator 1) 5. (335 aa)
wdr76WD repeat-containing protein 76; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. Belongs to the WD repeat DDB2/WDR76 family. (589 aa)
pole4Polymerase (DNA-directed), epsilon 4, accessory subunit. (131 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
LOC106919377UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (153 aa)
rpap3RNA polymerase II associated protein 3. (637 aa)
usp40Ubiquitin specific peptidase 40; Belongs to the peptidase C19 family. (1291 aa)
rad23aRAD23 homolog A, nucleotide excision repair protein a. (382 aa)
ercc3Excision repair cross-complementation group 3. (780 aa)
ENSPMEP00000014498Si:cabz01080528.1. (599 aa)
LOC106923389Ubiquitin-like domain-containing protein. (77 aa)
LOC106928565Si:ch73-290k24.6. (745 aa)
LOC106926030Uncharacterized protein. (166 aa)
tfptTCF3 (E2A) fusion partner. (199 aa)
rbx1Ring-box 1, E3 ubiquitin protein ligase. (108 aa)
gps1G protein pathway suppressor 1. (396 aa)
ube2nUbiquitin-conjugating enzyme E2Nb; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
polr2fPolymerase (RNA) II (DNA directed) polypeptide F. (127 aa)
pold1DNA polymerase. (1105 aa)
LOC106934012ATPase family AAA domain containing 5a. (1813 aa)
ppiePeptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily. (301 aa)
cops3COP9 signalosome subunit 3. (423 aa)
LOC106908123Uncharacterized protein. (375 aa)
LOC106915420Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (600 aa)
polr2jPolymerase (RNA) II (DNA directed) polypeptide J. (117 aa)
bivmBasic, immunoglobulin-like variable motif containing. (502 aa)
ddb2Damage-specific DNA binding protein 2. (492 aa)
kctd2Potassium channel tetramerization domain containing 2. (271 aa)
ino80INO80 complex ATPase subunit. (1038 aa)
LOC106905490MPN domain-containing protein. (276 aa)
ercc4Excision repair cross-complementation group 4. (892 aa)
LOC106926528Transcription elongation factor A (SII), 2. (319 aa)
gtf2h3General transcription factor IIH, polypeptide 3. (300 aa)
pold3Polymerase (DNA-directed), delta 3, accessory subunit. (438 aa)
parp2Poly [ADP-ribose] polymerase. (650 aa)
ZNF830Zinc finger protein 830. (335 aa)
cops8COP9 signalosome subunit 8. (191 aa)
ercc1Excision repair cross-complementation group 1. (356 aa)
LOC106929849SCY domain-containing protein. (125 aa)
sumo2Small ubiquitin-related modifier. (95 aa)
polr2lPolymerase (RNA) II (DNA directed) polypeptide L. (67 aa)
rps27aRibosomal protein S27a. (156 aa)
LOC106924789Protein inhibitor of activated STAT, 1a. (706 aa)
mnat1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (311 aa)
gtf2h4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (421 aa)
LOC106924837Centrin 4. (171 aa)
cops5COP9 signalosome subunit 5. (377 aa)
LOC106910889Rep_fac-A_C domain-containing protein. (220 aa)
tceanc2Uncharacterized protein. (218 aa)
actbUncharacterized protein. (375 aa)
LOC106910274General transcription factor IIH, polypeptide 2. (181 aa)
mcrs1Microspherule protein 1. (466 aa)
LOC106926296Si:ch73-1a9.3. (79 aa)
xrcc1X-ray repair complementing defective repair in Chinese hamster cells 1. (627 aa)
LOC106933455E1A binding protein p300 b. (2290 aa)
ENSPMEP00000026342Uncharacterized protein. (652 aa)
pole2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (528 aa)
LOC106920276Small ubiquitin-related modifier. (96 aa)
LOC106918268YY1 transcription factor. (422 aa)
chd1lChromodomain helicase DNA binding protein 1-like. (957 aa)
ercc8Excision repair cross-complementation group 8. (401 aa)
xpcXeroderma pigmentosum, complementation group C. (930 aa)
rfc1Replication factor C subunit 1. (1167 aa)
ENSPMEP00000024553Uncharacterized protein. (95 aa)
polr2iDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (126 aa)
polr2hDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
ENSPMEP00000023683Uncharacterized protein; Belongs to the actin family. (202 aa)
ino80eINO80 complex subunit E. (231 aa)
LOC106916471Von Willebrand factor A domain containing 5B2. (1013 aa)
aqrAquarius intron-binding spliceosomal factor. (1471 aa)
LOC106906886Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (638 aa)
ccnhCyclin H; Belongs to the cyclin family. (319 aa)
LOC106906894UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
meiobMethionine sulfoxide reductase B1b. (450 aa)
ercc2Excision repair cross-complementation group 2. (739 aa)
ENSPMEP00000021685Uncharacterized protein; Belongs to the actin family. (224 aa)
LOC106909028Uncharacterized protein. (375 aa)
rfc4Replication factor C (activator 1) 4. (358 aa)
nfrkbNuclear factor related to kappaB binding protein. (1277 aa)
YY1YY1 transcription factor b. (367 aa)
ruvbl1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
ube2v2Ubiquitin-conjugating enzyme E2 variant 2. (145 aa)
ube2iUbiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
polr2kPolymerase (RNA) II (DNA directed) polypeptide K. (58 aa)
LOC106906255RPA_C domain-containing protein. (255 aa)
xpaXeroderma pigmentosum, complementation group A. (275 aa)
ercc5Excision repair cross-complementation group 5. (1093 aa)
gtf2h1General transcription factor IIH, polypeptide 1. (550 aa)
Your Current Organism:
Poecilia mexicana
NCBI taxonomy Id: 48701
Other names: shortfin molly
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