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rfc3 rfc3 rpa3 rpa3 LOC106914577 LOC106914577 CPNE3 CPNE3 CPNE3-2 CPNE3-2 LOC106928274 LOC106928274 pole3 pole3 ENSPMEP00000000796 ENSPMEP00000000796 LOC106907485 LOC106907485 rnaseh2b rnaseh2b ENSPMEP00000002167 ENSPMEP00000002167 ENSPMEP00000002183 ENSPMEP00000002183 pola2 pola2 macrod1 macrod1 rnaseh2c rnaseh2c LOC106929990 LOC106929990 mcm7 mcm7 ENSPMEP00000003442 ENSPMEP00000003442 LOC106905247 LOC106905247 LOC106921684 LOC106921684 mcm2 mcm2 stn1 stn1 pcna pcna dna2 dna2 gen1 gen1 ENSPMEP00000007297 ENSPMEP00000007297 LOC106914548 LOC106914548 gdap2 gdap2 pola1 pola1 LOC106928751 LOC106928751 ENSPMEP00000008990 ENSPMEP00000008990 rnaseh2a rnaseh2a atad5 atad5 rfc2 rfc2 fen1 fen1 rpa2 rpa2 LOC106920738 LOC106920738 lig1 lig1 mcm9 mcm9 pold4 pold4 rfc5 rfc5 prim1 prim1 cpne7 cpne7 pole4 pole4 sass6 sass6 LOC106928627 LOC106928627 rnaseh1 rnaseh1 prim2 prim2 cpne2 cpne2 TOR1B TOR1B LOC106917389 LOC106917389 cabp5 cabp5 pold1 pold1 LOC106934012 LOC106934012 LOC106915448 LOC106915448 LOC106915420 LOC106915420 ppil3 ppil3 tor2a tor2a chrac1 chrac1 parp9 parp9 wrnip1 wrnip1 pold3 pold3 LOC106909064 LOC106909064 rfc4 rfc4 cpne4 cpne4 meiob meiob LOC106906886 LOC106906886 LOC106927661 LOC106927661 rfc1 rfc1 LOC106933539 LOC106933539 pole2 pole2 mcm6 mcm6 LOC106910889 LOC106910889 MCMDC2 MCMDC2 shd shd yju2 yju2 ssbp1 ssbp1 tor3a tor3a CPNE9 CPNE9 tor4a tor4a ENSPMEP00000030525 ENSPMEP00000030525 exoc8 exoc8 ENSPMEP00000032072 ENSPMEP00000032072 ENSPMEP00000032240 ENSPMEP00000032240 POLE POLE mcm3 mcm3 LOC106923171 LOC106923171 LOC106906255 LOC106906255 pold2 pold2 mcm4 mcm4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rfc3Replication factor C (activator 1) 3. (376 aa)
rpa3Replication protein A3. (122 aa)
LOC106914577Copine III. (539 aa)
CPNE3Copine 3. (554 aa)
CPNE3-2Copine 3. (541 aa)
LOC106928274Copine Va. (503 aa)
pole3Polymerase (DNA directed), epsilon 3 (p17 subunit). (150 aa)
ENSPMEP00000000796RAD17 checkpoint clamp loader component. (531 aa)
LOC106907485Uncharacterized protein. (485 aa)
rnaseh2bRibonuclease H2, subunit B. (306 aa)
ENSPMEP00000002167Poly [ADP-ribose] polymerase. (334 aa)
ENSPMEP00000002183Macro domain-containing protein. (221 aa)
pola2DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (606 aa)
macrod1Mono-ADP ribosylhydrolase 1. (406 aa)
rnaseh2cRibonuclease H2, subunit C. (136 aa)
LOC106929990Zgc:110269. (351 aa)
mcm7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (724 aa)
ENSPMEP00000003442PRKR interacting protein 1. (165 aa)
LOC106905247Family with sequence similarity 162 member A. (142 aa)
LOC106921684Si:dkey-102f14.5. (416 aa)
mcm2DNA helicase; Belongs to the MCM family. (886 aa)
stn1CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. (363 aa)
pcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (282 aa)
dna2Uncharacterized protein. (1356 aa)
gen1Chromo_2 domain-containing protein. (642 aa)
ENSPMEP00000007297Uncharacterized protein. (216 aa)
LOC106914548Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (221 aa)
gdap2Ganglioside induced differentiation associated protein 2. (495 aa)
pola1DNA polymerase. (1478 aa)
LOC106928751DNA helicase; Belongs to the MCM family. (683 aa)
ENSPMEP00000008990Uncharacterized protein. (137 aa)
rnaseh2aRibonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (255 aa)
atad5AAA domain-containing protein. (825 aa)
rfc2Replication factor C (activator 1) 2. (357 aa)
fen1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa)
rpa2Replication protein A2. (278 aa)
LOC106920738Copine VIII. (568 aa)
lig1DNA ligase. (1002 aa)
mcm9Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (951 aa)
pold4Si:dkey-28b4.7. (108 aa)
rfc5Replication factor C (activator 1) 5. (335 aa)
prim1DNA primase; Belongs to the eukaryotic-type primase small subunit family. (437 aa)
cpne7Copine VII. (561 aa)
pole4Polymerase (DNA-directed), epsilon 4, accessory subunit. (131 aa)
sass6Sas6_CC domain-containing protein. (473 aa)
LOC106928627Copine I. (534 aa)
rnaseh1Ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (295 aa)
prim2DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (508 aa)
cpne2Copine II. (547 aa)
TOR1BTorsin family 1 member B. (359 aa)
LOC106917389Copine Vb. (527 aa)
cabp5Calcium binding protein 5b. (169 aa)
pold1DNA polymerase. (1105 aa)
LOC106934012ATPase family AAA domain containing 5a. (1813 aa)
LOC106915448C2 domain-containing protein. (514 aa)
LOC106915420Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (600 aa)
ppil3Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (171 aa)
tor2aTorsin family 2, member A. (312 aa)
chrac1Chromatin accessibility complex subunit 1. (119 aa)
parp9Uncharacterized protein. (796 aa)
wrnip1WRN helicase interacting protein 1. (596 aa)
pold3Polymerase (DNA-directed), delta 3, accessory subunit. (438 aa)
LOC106909064C2 domain-containing protein. (153 aa)
rfc4Replication factor C (activator 1) 4. (358 aa)
cpne4Copine IVb. (554 aa)
meiobMethionine sulfoxide reductase B1b. (450 aa)
LOC106906886Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (638 aa)
LOC106927661DNA helicase; Belongs to the MCM family. (737 aa)
rfc1Replication factor C subunit 1. (1167 aa)
LOC106933539torsin-2A-like. (312 aa)
pole2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (528 aa)
mcm6DNA helicase; Belongs to the MCM family. (572 aa)
LOC106910889Rep_fac-A_C domain-containing protein. (220 aa)
MCMDC2Minichromosome maintenance domain containing 2. (669 aa)
shdSrc homology 2 domain containing transforming protein D, a. (417 aa)
yju2YJU2 splicing factor homolog. (341 aa)
ssbp1Single-stranded DNA binding protein 1. (147 aa)
tor3aTorsin family 3, member A. (367 aa)
CPNE9Copine family member 9. (543 aa)
tor4aTorsin family 4, member Aa. (440 aa)
ENSPMEP00000030525Uncharacterized protein. (103 aa)
exoc8Exocyst complex component 8. (685 aa)
ENSPMEP00000032072Mono-ADP ribosylhydrolase 2. (243 aa)
ENSPMEP00000032240DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (364 aa)
POLEDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (1123 aa)
mcm3DNA helicase; Belongs to the MCM family. (815 aa)
LOC106923171Poly [ADP-ribose] polymerase. (1804 aa)
LOC106906255RPA_C domain-containing protein. (255 aa)
pold2Polymerase (DNA directed), delta 2, regulatory subunit. (468 aa)
mcm4DNA helicase; Belongs to the MCM family. (868 aa)
Your Current Organism:
Poecilia mexicana
NCBI taxonomy Id: 48701
Other names: shortfin molly
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