STRINGSTRING
ercc4 ercc4 cetn2 cetn2 rfc3 rfc3 rpa3 rpa3 pole3 pole3 LOC106904547 LOC106904547 ddx11 ddx11 ENSPMEP00000003442 ENSPMEP00000003442 ercc6 ercc6 stn1 stn1 ENSPMEP00000006549 ENSPMEP00000006549 pcna pcna ddb1 ddb1 atad5 atad5 rfc2 rfc2 rpa2 rpa2 cul4a cul4a lig1 lig1 pold4 pold4 rfc5 rfc5 wdr76 wdr76 pole4 pole4 sass6 sass6 rad23a rad23a ercc3 ercc3 rbx1 rbx1 cabp5 cabp5 pold1 pold1 LOC106934012 LOC106934012 LOC106915420 LOC106915420 bivm bivm fbh1 fbh1 ddb2 ddb2 ppil3 ppil3 chrac1 chrac1 gtf2h3 gtf2h3 pold3 pold3 fbxw12 fbxw12 rfc4 rfc4 ercc2 ercc2 meiob meiob ccnh ccnh LOC106906886 LOC106906886 clspn clspn rfc1 rfc1 xpc xpc ercc8 ercc8 pole2 pole2 LOC106910274 LOC106910274 LOC106910889 LOC106910889 LOC106924837 LOC106924837 shd shd yju2 yju2 gtf2h4 gtf2h4 mnat1 mnat1 ercc1 ercc1 gtf2h5 gtf2h5 ENSPMEP00000031841 ENSPMEP00000031841 ENSPMEP00000032240 ENSPMEP00000032240 POLE POLE cdk7 cdk7 LOC106908444 LOC106908444 LOC106911701 LOC106911701 LOC106906255 LOC106906255 cdk20 cdk20 xpa xpa ercc5 ercc5 gtf2h1 gtf2h1 pold2 pold2 cul4b cul4b LOC106925147 LOC106925147
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ercc4Excision repair cross-complementation group 4. (892 aa)
cetn2Centrin, EF-hand protein, 2. (229 aa)
rfc3Replication factor C (activator 1) 3. (376 aa)
rpa3Replication protein A3. (122 aa)
pole3Polymerase (DNA directed), epsilon 3 (p17 subunit). (150 aa)
LOC106904547RAD23 homolog B, nucleotide excision repair protein. (392 aa)
ddx11DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11. (902 aa)
ENSPMEP00000003442PRKR interacting protein 1. (165 aa)
ercc6Excision repair cross-complementation group 6. (1446 aa)
stn1CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. (363 aa)
ENSPMEP00000006549Uncharacterized protein. (264 aa)
pcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (282 aa)
ddb1Damage-specific DNA binding protein 1. (1139 aa)
atad5AAA domain-containing protein. (825 aa)
rfc2Replication factor C (activator 1) 2. (357 aa)
rpa2Replication protein A2. (278 aa)
cul4aCullin 4A; Belongs to the cullin family. (646 aa)
lig1DNA ligase. (1002 aa)
pold4Si:dkey-28b4.7. (108 aa)
rfc5Replication factor C (activator 1) 5. (335 aa)
wdr76WD repeat-containing protein 76; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. Belongs to the WD repeat DDB2/WDR76 family. (589 aa)
pole4Polymerase (DNA-directed), epsilon 4, accessory subunit. (131 aa)
sass6Sas6_CC domain-containing protein. (473 aa)
rad23aRAD23 homolog A, nucleotide excision repair protein a. (382 aa)
ercc3Excision repair cross-complementation group 3. (780 aa)
rbx1Ring-box 1, E3 ubiquitin protein ligase. (108 aa)
cabp5Calcium binding protein 5b. (169 aa)
pold1DNA polymerase. (1105 aa)
LOC106934012ATPase family AAA domain containing 5a. (1813 aa)
LOC106915420Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (600 aa)
bivmBasic, immunoglobulin-like variable motif containing. (502 aa)
fbh1F-box DNA helicase 1. (1057 aa)
ddb2Damage-specific DNA binding protein 2. (492 aa)
ppil3Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (171 aa)
chrac1Chromatin accessibility complex subunit 1. (119 aa)
gtf2h3General transcription factor IIH, polypeptide 3. (300 aa)
pold3Polymerase (DNA-directed), delta 3, accessory subunit. (438 aa)
fbxw12Si:ch73-142c19.1. (474 aa)
rfc4Replication factor C (activator 1) 4. (358 aa)
ercc2Excision repair cross-complementation group 2. (739 aa)
meiobMethionine sulfoxide reductase B1b. (450 aa)
ccnhCyclin H; Belongs to the cyclin family. (319 aa)
LOC106906886Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (638 aa)
clspnUncharacterized protein. (859 aa)
rfc1Replication factor C subunit 1. (1167 aa)
xpcXeroderma pigmentosum, complementation group C. (930 aa)
ercc8Excision repair cross-complementation group 8. (401 aa)
pole2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (528 aa)
LOC106910274General transcription factor IIH, polypeptide 2. (181 aa)
LOC106910889Rep_fac-A_C domain-containing protein. (220 aa)
LOC106924837Centrin 4. (171 aa)
shdSrc homology 2 domain containing transforming protein D, a. (417 aa)
yju2YJU2 splicing factor homolog. (341 aa)
gtf2h4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (421 aa)
mnat1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (311 aa)
ercc1Excision repair cross-complementation group 1. (356 aa)
gtf2h5General transcription factor IIH, polypeptide 5. (71 aa)
ENSPMEP00000031841annotation not available (264 aa)
ENSPMEP00000032240DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (364 aa)
POLEDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (1123 aa)
cdk7Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (360 aa)
LOC106908444C2H2-type domain-containing protein. (1324 aa)
LOC106911701General transcription factor IIH, polypeptide 2. (169 aa)
LOC106906255RPA_C domain-containing protein. (255 aa)
cdk20Cyclin-dependent kinase 20; Belongs to the protein kinase superfamily. (352 aa)
xpaXeroderma pigmentosum, complementation group A. (275 aa)
ercc5Excision repair cross-complementation group 5. (1093 aa)
gtf2h1General transcription factor IIH, polypeptide 1. (550 aa)
pold2Polymerase (DNA directed), delta 2, regulatory subunit. (468 aa)
cul4bCullin 4B; Belongs to the cullin family. (868 aa)
LOC106925147Zinc finger protein 609b. (1107 aa)
Your Current Organism:
Poecilia mexicana
NCBI taxonomy Id: 48701
Other names: shortfin molly
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