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| | DKAM_0744 | Putative transcriptional regulatory protein. (135 aa) |
| | DKAM_0754 | DEAD/DEAH box helicase domain protein. (762 aa) |
| | DKAM_0780 | DUF83 domain containing protein; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family. (173 aa) |
| | cas2 | CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (95 aa) |
| | cas1 | CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (328 aa) |
| | DKAM_0792 | CRISPR-associated (Cas) DxTHG family protein; COG1517,(Csx1). (486 aa) |
| | cysS | cysteinyl-tRNA synthetase. (481 aa) |
| | DKAM_0805 | Endonuclease (RecB family)-like protein. (233 aa) |
| | DKAM_0806 | COG1533 DNA repair photolyase; pfam04055, Radical_SAM, Radical SAM superfamily. (381 aa) |
| | DKAM_0811 | N2,N2-dimethylguanosine tRNA methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. (396 aa) |
| | flpA | Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. (237 aa) |
| | DKAM_0016 | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (255 aa) |
| | DKAM_0028 | Translin. (244 aa) |
| | DKAM_0032 | Phosphatases-like protein. (227 aa) |
| | DKAM_0034 | TatD-related deoxyribonuclease. (236 aa) |
| | DKAM_0039 | Putative translation factor; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. (359 aa) |
| | DKAM_0040 | Putative circadian clock protein, KaiC. (262 aa) |
| | tmcA | Predicted P-loop ATPase fused to an acetyltransferase; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP). (814 aa) |
| | DKAM_0043 | Putative circadian clock protein, KaiC; Belongs to the UPF0273 family. (260 aa) |
| | DKAM_0047 | tRNA-splicing endonuclease. (98 aa) |
| | DKAM_0052 | Glycyl-tRNA synthetase. (583 aa) |
| | DKAM_0054 | DNA-directed RNA polymerase subunit P. (49 aa) |
| | tfb | Transcription initiation factor IIB (TFIIB); Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). (319 aa) |
| | DKAM_0059 | Threonyl/alanyl tRNA synthetase. (235 aa) |
| | DKAM_0094 | Small nuclear ribonucleoprotein, LSM family. (93 aa) |
| | DKAM_0096 | Protein of unknown function DUF91. (80 aa) |
| | DKAM_0104 | Indolepyruvate ferredoxin oxidoreductase, alpha subunit. (145 aa) |
| | DKAM_0106 | Exonuclease of the beta-lactamase fold involved in RNA processing-like protein. (362 aa) |
| | DKAM_0112 | Phospholipase D-related protein. (197 aa) |
| | DKAM_0114 | IS element ISDka1 orfB, putative transposase. (404 aa) |
| | rgy | Reverse gyrase; Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication; In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family. (1334 aa) |
| | DKAM_0847 | methionyl-tRNA synthetase, beta subunit. (108 aa) |
| | taw3 | TYW3 domain containing protein; S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72; Belongs to the TYW3 family. (220 aa) |
| | DKAM_0852 | Hypothetical protein. (65 aa) |
| | dtdA | tRNA_deacylase domain containing protein; D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo. (272 aa) |
| | nfi | Endonuclease V; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. (219 aa) |
| | priL | DNA primase, large subunit; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. (381 aa) |
| | aspS | aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). (420 aa) |
| | DKAM_0922 | Transcription initiation factor TFIIIB. (262 aa) |
| | DKAM_0923 | Hypothetical protein. (83 aa) |
| | DKAM_0960 | ISC1913-like resolvase. (103 aa) |
| | DKAM_0961 | Nuclease (SNase domain protein); COG1525 Micrococcal nuclease (thermonuclease) homologs. (837 aa) |
| | DKAM_0981 | CRISPR-associated protein Cas4; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family. (214 aa) |
| | DKAM_0986 | Endonuclease IV. (288 aa) |
| | DKAM_0991 | Putative uncharacterized protein; Pfam00430, ATP-synt_B, ATP synthase B/B' CF(0). (97 aa) |
| | proS | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (479 aa) |
| | xerA | Phage integrase family protein; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Belongs to the 'phage' integrase family. XerA subfamily. (321 aa) |
| | DKAM_1005 | Phosphoesterase, DHHA1. (321 aa) |
| | DKAM_1032 | Transposase, IS605 OrfB family; Probably pseudogene. (124 aa) |
| | rpoK | DNA-directed RNA polymerase subunit K; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit family. (106 aa) |
| | topA | DNA topoisomerase I family A; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing [...] (679 aa) |
| | DKAM_1042 | IS element ISDka1 orfA, putative resolvase. (216 aa) |
| | DKAM_1043 | IS element ISDka1 orfB, putative transposase. (429 aa) |
| | DKAM_1053 | valyl-tRNA synthetase. (817 aa) |
| | DKAM_1054 | Predicted metal-dependent phosphoesterases (PHP family). (232 aa) |
| | DKAM_1057 | Metal dependent phosphohydrolase. (208 aa) |
| | DKAM_1058 | N-glycosylase/DNA lyase. (283 aa) |
| | DKAM_1063 | RNA (Cytosine-C(5)-)-methyltransferase. (386 aa) |
| | DKAM_1064 | COG1439 Predicted nucleic acid-binding protein, consists of a PIN domain and a Zn-ribbon module. (172 aa) |
| | DKAM_1066 | Predicted methyltransferase. (333 aa) |
| | fen | Flap structure-specific endonuclease; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair [...] (363 aa) |
| | DKAM_1074 | Putative transcription elongation factor, nusA. (143 aa) |
| | DKAM_1075 | tRNA pseudouridine synthase D. (370 aa) |
| | DKAM_1082 | RNA modification enzyme, MiaB family. (432 aa) |
| | DKAM_1088 | Predicted RNA-binding protein (contains KH domains). (211 aa) |
| | alaS | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (908 aa) |
| | DKAM_1115 | COG1534 Predicted RNA-binding protein containing KH domain, possibly ribosomal protein. (97 aa) |
| | rnp4 | RNAse P, Rpr2/Rpp21 subunit; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. (125 aa) |
| | nep1 | Probable ribosome biogenesis protein NEP1-like protein; Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA. (234 aa) |
| | DKAM_1118 | Anaerobic ribonucleoside triphosphate reductase; Protein product contain self-splicing intein. (848 aa) |
| | DKAM_1125 | Primase. (598 aa) |
| | DKAM_1139 | Pfam01951, DUF101, Protein of unknown function DUF101. (155 aa) |
| | truB | tRNA pseudouridine synthase; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily. (345 aa) |
| | rnp1 | Ribonuclease P protein component 1, Rpp29; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 1 family. (92 aa) |
| | DKAM_1180 | DEAD/DEAH box helicase domain protein. (932 aa) |
| | pcn-2 | DNA polymerase sliding clamp B1; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family. (254 aa) |
| | DKAM_1192 | Protein of unknown function DUF701, zinc-binding putative. (119 aa) |
| | DKAM_1196 | Hypothetical protein. (37 aa) |
| | DKAM_1203 | Predicted endonuclease-methyltransferase fusion protein. (1241 aa) |
| | rtcB | Protein of unknown function UPF0027; Belongs to the RtcB family. (482 aa) |
| | hisS | histidyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. (440 aa) |
| | DKAM_1212 | tRNA intron endonuclease, catalytic-like protein. (178 aa) |
| | radA | DNA repair and recombination protein radA; Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules. (328 aa) |
| | thrS | threonyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. (614 aa) |
| | top6A | Type 2 DNA topoisomerase VI subunit A; Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family. (433 aa) |
| | top6B | Type 2 DNA topoisomerase VI subunit B; Relaxes both positive and negative superturns and exhibits a strong decatenase activity. (530 aa) |
| | rgy-2 | Reverse gyrase; Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication; In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family. (1212 aa) |
| | DKAM_1235 | DUF367 containing protein; Probable pre-rRNA processing protein involved in ribosome biogenesis; Belongs to the TSR3 family. (174 aa) |
| | tyrS | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 4 subfamily. (361 aa) |
| | DKAM_1244 | IS element ISDka1 orfB, putative transposase; C-terminal shortening, may be pseudogene. (325 aa) |
| | DKAM_1245 | IS element ISDka1 orfA, putative resolvase. (214 aa) |
| | DKAM_1249 | COG1594 DNA-directed RNA polymerase, subunit M / Transcription elongation factor TFIIS. (100 aa) |
| | DKAM_1256 | Prefoldin, molecular chaperone implicated in de novo protein folding, alpha subunit. (163 aa) |
| | tgtA | tRNA-guanine transglycosylase, various specificities; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. (520 aa) |
| | DKAM_1259 | Small nuclear ribonucleoprotein (snRNP) - like protein. (149 aa) |
| | DKAM_1264 | RecB-family nuclease-like protein; COG4080 RecB-family nuclease. (150 aa) |
| | tfe | Transcription factor TFIIE, alpha subunit; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongatio [...] (159 aa) |
| | DKAM_1271 | SpoU-like RNA methylase; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. (179 aa) |
| | DKAM_1281 | COG4113 Predicted nucleic acid-binding protein, contains PIN domain. (135 aa) |
| | rtcA | Probable RNA 3'-terminal phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing. (357 aa) |
| | DKAM_1287 | mRNA 3'-end polyadenylation factor; COG1782 Predicted metal-dependent RNase, consists of a metallo-beta-lactamase domain and an RNA-binding KH domain; pfam00753, Lactamase_B, Metallo-beta-lactamase superfamily. (647 aa) |
| | dnaG | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. (408 aa) |
| | DKAM_1294 | Small nuclear ribonucleoprotein (snRNP) - like protein. (75 aa) |
| | DKAM_1295 | COG0417 DNA polymerase elongation subunit (family B); pfam00136, DNA_pol_B, DNA polymerase family B; pfam03104, DNA_pol_B_exo, DNA polymerase family B, exonuclease domain; smart00486, POLBc, DNA polymerase type-B family; DNA polymerase alpha, delta, epsilon and zeta chain (eukaryota), DNA polymerases in archaea. (797 aa) |
| | pelA | Putative translation factor Pelota - like protein; May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity. (356 aa) |
| | DKAM_1308 | Methyltransferase type 11; COG2519 tRNA(1-methyladenosine) methyltransferase and related methyltransferases. (265 aa) |
| | DKAM_1314 | COG0417 DNA polymerase elongation subunit (family B); pfam00136, DNA_pol_B, DNA polymerase family B; pfam03104, DNA_pol_B_exo, DNA polymerase family B, exonuclease domain; smart00486, POLBc, DNA polymerase type-B family; DNA polymerase alpha, delta, epsilon and zeta chain (eukaryota), DNA polymerases in archaea. (856 aa) |
| | DKAM_1316 | COG1236 Predicted exonuclease of the beta-lactamase fold involved in RNA processing. (425 aa) |
| | DKAM_1320 | Hypothetical protein. (74 aa) |
| | DKAM_1321 | Probable brix domain-containing ribosomal biogenesis protein; Probably involved in the biogenesis of the ribosome. (177 aa) |
| | rrp42 | Probable exosome complex exonuclease 2; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site. (286 aa) |
| | rrp41 | Probable exosome complex exonuclease 1; Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails. (242 aa) |
| | rrp4 | Exosome complex RNA-binding protein Rrp4; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome. (239 aa) |
| | rnp2 | Ribonuclease P protein component 2; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 2 family. (155 aa) |
| | DKAM_1329 | COG1603 RNase P/RNase MRP subunit p30. (208 aa) |
| | DKAM_1337 | Phosphoesterase, RecJ domain protein. (373 aa) |
| | DKAM_1340 | Mn2+-dependent serine/threonine protein kinase. (225 aa) |
| | kae1 | Putative O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37; Belongs to the KAE1 / TsaD family. (355 aa) |
| | DKAM_1345 | DNA-directed RNA polymerase subunit E'. (190 aa) |
| | DKAM_1346 | Predicted nucleic acid-binding protein, containing PIN domain; COG1412 Uncharacterized proteins of PilT N-term./Vapc superfamily. (140 aa) |
| | rpl7ae | 50S ribosomal protein L7Ae; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs. (127 aa) |
| | gltX | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (578 aa) |
| | rpoN | DNA-directed RNA polymerase subunit N; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoN/eukaryotic RPB10 RNA polymerase subunit family. (76 aa) |
| | rpoD | DNA-directed RNA polymerase subunit D; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoD/eukaryotic RPB3 RNA polymerase subunit family. (280 aa) |
| | nusA | NusA family KH domain protein; Participates in transcription termination. Belongs to the NusA family. (148 aa) |
| | rpoA2 | DNA-directed RNA polymerase, subunit A'; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (406 aa) |
| | DKAM_1374 | DNA-directed RNA polymerase subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (886 aa) |
| | DKAM_1375 | DNA-directed RNA polymerase, subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1149 aa) |
| | rpoH | DNA-directed RNA polymerase subunit H; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family. (83 aa) |
| | cdc6 | Cell division control protein 6 - like protein, cdc6; Involved in regulation of DNA replication. (394 aa) |
| | DKAM_1400 | COG1672 Predicted ATPase (AAA+ superfamily). (370 aa) |
| | DKAM_1403 | COG0565 rRNA methylase. (234 aa) |
| | DKAM_1405 | COG0030 Dimethyladenosine transferase (rRNA methylation); Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (278 aa) |
| | DKAM_1407 | Pfam03874, RNA_pol_Rpb4, RNA polymerase Rpb4; pfam09417, RNA_pol_III_C17, RNA polymerase III subunit C17; smart00657, RPOL4c, DNA-directed RNA-polymerase II subunit. (124 aa) |
| | pus10 | Predicted pseudouridylate synthase; Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs. (447 aa) |
| | csl4 | Predicted RNA-binding protein (consists of S1 domain and a Zn-ribbon domain); Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. (181 aa) |
| | DKAM_1416 | DNA-directed RNA polymerase, subunit L. (93 aa) |
| | DKAM_1418 | DNA-directed RNA polymerase subunit M. (75 aa) |
| | pcn-3 | DNA polymerase sliding clamp subunit B2 (PCNA - like protein); Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. (249 aa) |
| | priS | Probable DNA primase small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer sy [...] (374 aa) |
| | nop10 | Nucleolar RNA-binding protein Nop10p; Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA. (66 aa) |
| | DKAM_1426 | Hypothetical protein. (164 aa) |
| | DKAM_1427 | Cell division control protein 6 - like protein, cdc6; Involved in regulation of DNA replication. (414 aa) |
| | DKAM_1457 | COG0180 Tryptophanyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (371 aa) |
| | DKAM_1464 | TatD-related deoxyribonuclease; Pfam01026, TatD_DNase, TatD related DNase; COG1831 Predicted metal-dependent hydrolase (urease superfamily). (281 aa) |
| | DKAM_1473 | IS element ISDka1 orfA, putative resolvase. (216 aa) |
| | DKAM_1474 | IS element ISDka1 orfB, putative transposase. (432 aa) |
| | DKAM_0115 | IS element ISDka1 orfA, putative resolvase. (214 aa) |
| | DKAM_0125 | Histone acetyltransferase, ELP3 family. (491 aa) |
| | DKAM_0140 | Uncharacterized Zn-finger containing protein. (120 aa) |
| | DKAM_0145 | Putative GTPase or GTP-binding protein. (397 aa) |
| | DKAM_0147 | AAA ATPase. (206 aa) |
| | DKAM_0151 | Putative ATP-dependent helicase. (886 aa) |
| | DKAM_0161 | Phosphoesterase, DHHA1. (340 aa) |
| | DKAM_0189 | phenylalanyl-tRNA synthetase subunit beta. (557 aa) |
| | DKAM_0194 | Pfam01035, DNA_binding_1, 6-O-methylguanine DNA methyltransferase, DNA binding domain. (94 aa) |
| | DKAM_0223 | Radical SAM domain protein. (231 aa) |
| | PheS | pheS; phenylalanyl-tRNA synthetase subunit alpha. (520 aa) |
| | DKAM_0238 | Radical SAM domain protein; COG0731 Fe-S oxidoreductases. (310 aa) |
| | DKAM_0246 | IS element ISDka1 orfB, putative transposase. (429 aa) |
| | DKAM_0247 | IS element ISDka1 orfA, putative resolvase. (214 aa) |
| | DKAM_0251 | Hypothetical protein; COG1720 Uncharacterized conserved protein;~pfam01980, UPF0066, Uncharacterised protein family UPF0066. (173 aa) |
| | tbp | Transcription factor - TATA-box-binding protein; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation. (194 aa) |
| | lig | ATP-dependent DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. (610 aa) |
| | DKAM_0281 | Predicted uracil-DNA glycosylase; K02334 DNA polymerase bacteriophage-type. (216 aa) |
| | cca | tRNA nucleotidyltransferase (CCA-adding enzyme); Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. (466 aa) |
| | pcn | DNA polymerase sliding clamp A; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. (246 aa) |
| | DKAM_0328 | Methyltransferase; COG2520 Predicted methyltransferase. (286 aa) |
| | DKAM_0329 | Endonuclease III; HhH-GPD family protein; K01741 DNA-(apurinic or apyrimidinic site) lyase; COG0177 Predicted EndoIII-related endonuclease. (238 aa) |
| | DKAM_0330 | asparaginyl-tRNA synthetase. (432 aa) |
| | DKAM_0333 | Transposase, IS605 OrfB family; Probably pseudogene. (98 aa) |
| | DKAM_0354 | Putative uncharacterized protein; COG2404 Predicted phosphohydrolase (DHH superfamily). (314 aa) |
| | DKAM_0360 | Metallophosphoesterase; K06953; COG1407 Predicted ICC-like phosphoesterases. (300 aa) |
| | DKAM_0367 | Iron-sulfur cluster loop. (317 aa) |
| | DKAM_0379 | Protein of unknown function DUF650; Involved in DNA damage repair; Belongs to the Nre family. (413 aa) |
| | DKAM_0380 | DNA repair photolyase; Radical SAM domain protein. (265 aa) |
| | DKAM_0437 | tRNA synthetase, class II (D, K and N); COG0017 Aspartyl/asparaginyl-tRNA synthetases. (388 aa) |
| | DKAM_0438 | IS element ISDka1 orfA, putative resolvase. (214 aa) |
| | DKAM_0439 | IS element ISDka1 orfB, putative transposase. (429 aa) |
| | fau-1 | RNA-loop binding protein FAU-1; Probable RNase involved in rRNA stability through maturation and/or degradation of precursor rRNAs. Binds to RNA in loop regions with AU-rich sequences. (474 aa) |
| | serS | Seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (459 aa) |
| | tiaS | Predicted DNA-binding protein; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA. (451 aa) |
| | DKAM_0485 | Pfam01555, N6_N4_Mtase, DNA methylase; COG0863 DNA modification methylase. (317 aa) |
| | DKAM_0492 | COG0037 Predicted ATPase of the PP-loop superfamily implicated in cell cycle control. (339 aa) |
| | DKAM_0500 | Arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (758 aa) |
| | rnz | Beta-lactamase domain protein; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family. (249 aa) |
| | DKAM_0539 | Putative RNA methylase; COG3432 Predicted transcriptional regulator; COG3432 Predicted transcriptional regulator. (340 aa) |
| | DKAM_0543 | Heavy metal translocating P-type ATPase; COG2217 Cation transport ATPase; pfam00702, Hydrolase, haloacid dehalogenase-like hydrolase; pfam08282, Hydrolase_3, haloacid dehalogenase-like hydrolase. (202 aa) |
| | DKAM_0547 | methionyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (498 aa) |
| | DKAM_0556 | IS element ISDka1 orfA, putative resolvase. (218 aa) |
| | DKAM_0557 | IS element ISDka1 orfB, putative transposase; Probably pseudogene. (246 aa) |
| | DKAM_0563 | Hypothetical protein. (48 aa) |
| | DKAM_0586 | Pfam01189, Nol1_Nop2_Fmu, NOL1/NOP2/sun family; COG0144 tRNA and rRNA cytosine-C5-methylases. (340 aa) |
| | ileS | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1058 aa) |
| | DKAM_0609 | Methyltransferase type 12; COG0500 SAM-dependent methyltransferases. (221 aa) |
| | DKAM_0610 | DNA double-strand break repair rad50 ATPase; SMC domain protein. (818 aa) |
| | DKAM_0613 | DNA double-strand break repair protein mre11; COG0420 DNA repair exonuclease. (427 aa) |
| | lysS | lysyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (546 aa) |
| | DKAM_0624 | leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (971 aa) |
| | hjc | Holliday junction resolvase; A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products; Belongs to the Holliday junction resolvase Hjc family. (146 aa) |
| | taw1 | Wyosine base formation; Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe). (364 aa) |
| | DKAM_0663 | Single-strand DNA-binding protein. (158 aa) |
| | DKAM_0664 | Endonuclease III (nth1). (165 aa) |
| | DKAM_0671 | Hypothetical protein. (177 aa) |
| | DKAM_0676 | ERCC4 domain protein; Repair endonuclease XPF (Aeropyrum pernix)homolog. (238 aa) |
| | DKAM_0681 | IS element ISDka2 orfA. (118 aa) |
| | DKAM_0682 | IS element ISDka2 orfB. (437 aa) |
| | DKAM_0687 | MCM family protein; COG1241 Predicted ATPase involved in replication control, Cdc46/Mcm family; Belongs to the MCM family. (700 aa) |
| | rfcS | Replication factor C small subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcS subfamily. (326 aa) |
| | rfcL | Replication factor C large subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcL subfamily. (426 aa) |
| | thiI | Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (482 aa) |
| | hel308 | DEAD/DEAH box helicase domain protein; DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks. (717 aa) |
| | DKAM_0722 | ATPase, PP-loop superfamily. (321 aa) |
