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glnQ glnQ cstA cstA qoxA qoxA qoxB qoxB qoxC qoxC cysP cysP Aflv_0324 Aflv_0324 Aflv_0433 Aflv_0433 Aflv_0554 Aflv_0554 secF secF pstC pstC pstA pstA pstBB pstBB cobD-2 cobD-2 Aflv_2822 Aflv_2822 Aflv_1141 Aflv_1141 Aflv_1150 Aflv_1150 Aflv_1167 Aflv_1167 Aflv_1218 Aflv_1218 rbsA rbsA Aflv_1326 Aflv_1326 Aflv_1327 Aflv_1327 Aflv_1336 Aflv_1336 nosY nosY ctaD ctaD Aflv_1360 Aflv_1360 Aflv_1388 Aflv_1388 alsT alsT Aflv_1406 Aflv_1406 alsT-2 alsT-2 treP treP gltT gltT fruA fruA mtlR mtlR mtlA-2 mtlA-2 Aflv_1593 Aflv_1593 msmX msmX Aflv_1657 Aflv_1657 fliI fliI Aflv_1797 Aflv_1797 Aflv_1863 Aflv_1863 ctaF ctaF ctaE ctaE ctaD-2 ctaD-2 ctaC ctaC ptsG ptsG mrpG mrpG mrpF mrpF mrpE mrpE mrpD mrpD mrpC mrpC mrpB mrpB mrpA mrpA msmX-3 msmX-3 Aflv_1989 Aflv_1989 rbsA-2 rbsA-2 Aflv_2022 Aflv_2022 cobQ cobQ Aflv_2189 Aflv_2189 Aflv_2190 Aflv_2190 Aflv_2194 Aflv_2194 Aflv_2273 Aflv_2273 msmX-2 msmX-2 Aflv_2307 Aflv_2307 araP araP Aflv_2428 Aflv_2428 metN metN secG secG secA secA sunT sunT secA-2 secA-2 rbsA-3 rbsA-3 nuoN nuoN nuoM nuoM nuoL nuoL nuoJ nuoJ nuoC nuoC nuoB nuoB nuoA nuoA atpD atpD atpA atpA ahpF ahpF Aflv_2781 Aflv_2781 sacP sacP
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
glnQABC-type glutamine transport system, ATPase component. (240 aa)
cstACarbon starvation membrane protein. (539 aa)
qoxACytochrome aa3 quinol oxidase subunit II; Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I. (324 aa)
qoxBCytochrome aa3 quinol oxidase subunit I; Belongs to the heme-copper respiratory oxidase family. (665 aa)
qoxCCytochrome aa3 quinol oxidase subunit III. (201 aa)
cysPSulfate permease. (348 aa)
Aflv_0324Ca2+/H+ antiporter; Ca(+)/H(+) antiporter that extrudes calcium in exchange for external protons. (349 aa)
Aflv_0433Maltose permease, MFS type. (383 aa)
Aflv_0554Permease, involved in lantibiotic resistance. (147 aa)
secFPreprotein translocase subunits SecDF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. (748 aa)
pstCABC-type phosphate transport system, permease component; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (337 aa)
pstAABC-type phosphate transport system, permease component. (293 aa)
pstBBABC-type phosphate transport system, ATPase component; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. (269 aa)
cobD-2Cobalamin biosynthesis protein CobD/CbiB; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (310 aa)
Aflv_2822Spermidine/putrescine transport system permease protein. (270 aa)
Aflv_1141Predicted sulfate permease MFS superfamily. (581 aa)
Aflv_1150Uncharacterized conserved protein. (298 aa)
Aflv_1167Kef-type K+ transport system (membrane and NAD-binding components); Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. (608 aa)
Aflv_1218Cation transport ATPase. (803 aa)
rbsAABC-type ribose transport system, ATPase component; Part of the ABC transporter complex XylFGH involved in xylose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Xylose importer (TC 3.A.1.2.4) family. (517 aa)
Aflv_1326ABC-type multidrug transport system, ATPase and permease component. (584 aa)
Aflv_1327ABC-type multidrug transport system, ATPase and permease component. (609 aa)
Aflv_1336Cation transport ATPase, contains heavy metal-binding domain. (689 aa)
nosYABC-type transport system involved in multi-copper enzyme maturation, permease component. (269 aa)
ctaDCytochrome c oxidase (b(o/a)3-type) chain I; Belongs to the heme-copper respiratory oxidase family. (549 aa)
Aflv_1360Cytochrome c oxidase (b(o/a)3-type) chain II. (157 aa)
Aflv_1388Na+-driven multidrug efflux pump. (446 aa)
alsTNa+/alanine symporter. (474 aa)
Aflv_1406ABC-type multidrug transport system, permease component. (326 aa)
alsT-2Na+/alanine symporter. (477 aa)
trePPhosphotransferase system (PTS) trehalose-specific enzyme II, BC component. (467 aa)
gltTProton/sodium-glutamate symport protein; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. (408 aa)
fruAPhosphotransferase system (PTS) fructose-specific enzyme II, ABC subunits. (620 aa)
mtlRTranscriptional antiterminator of mannitol metabolism. (691 aa)
mtlA-2Phosphotransferase system (PTS) mannitol-specific IIBC component. (466 aa)
Aflv_1593ABC-type glycerol-3-phosphate transport system permease component. (292 aa)
msmXABC-type glycerol-3-phosphate transport system, ATPase component; Belongs to the ABC transporter superfamily. (366 aa)
Aflv_1657Sulfate permease. (489 aa)
fliIFlagellar biosynthesis/type III secretory pathway ATPase FliI. (437 aa)
Aflv_1797Cation transport ATPase. (889 aa)
Aflv_1863Predicted membrane protein. (154 aa)
ctaFCytochrome caa3 oxidase (subunit IV). (110 aa)
ctaECytochrome caa3 oxidase (subunit III). (206 aa)
ctaD-2Cytochrome caa3 oxidase (subunit I); Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (622 aa)
ctaCCytochrome caa3 oxidase (subunit II); Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B). (354 aa)
ptsGPhosphotransferase system (PTS) glucose-specific enzyme IICBA component. (663 aa)
mrpGMultisubunit Na+/H+ antiporter, G subunit. (119 aa)
mrpFMultisubunit Na+/H+ antiporter, F subunit. (91 aa)
mrpEMultisubunit Na+/H+ antiporter, E subunit. (158 aa)
mrpDMultisubunit Na+/H+ antiporter, D subunit. (490 aa)
mrpCMultisubunit Na+/H+ antiporter, C subunit. (110 aa)
mrpBMultisubunit Na+/H+ antiporter, B subunit. (140 aa)
mrpAMultisubunit Na+/H+ antiporter, A subunit. (821 aa)
msmX-3Spermidine/putrescine transport system ATP-binding protein; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family. (330 aa)
Aflv_1989Amino acid transporter. (506 aa)
rbsA-2ABC-type sugar transport system, ATPase component. (497 aa)
Aflv_2022ABC-type sugar transport system, permease component. (296 aa)
cobQCobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (504 aa)
Aflv_2189ABC-type maltose/maltodextrin transport system, permease component. (280 aa)
Aflv_2190ABC-type maltose/maltodextrin transport system, permease component. (440 aa)
Aflv_2194Na+-driven multidrug efflux pump. (450 aa)
Aflv_2273ABC-type sugar transport system, permease component. (431 aa)
msmX-2ABC-type sugar transport system, ATPase component; Belongs to the ABC transporter superfamily. (370 aa)
Aflv_2307ABC-type amino acid transport system, ATPase component. (254 aa)
araPABC-type sugar transport system, permease component. (308 aa)
Aflv_2428Na+-dependent transporters of the SNF family. (503 aa)
metNABC-type metal ion transport system, ATPase component; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. (342 aa)
secGPreprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. (82 aa)
secAPreprotein translocase subunit SecA (ATPase, RNA helicase); Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. (856 aa)
sunTABC-type bacteriocin/lantibiotic exporter; Contains an N-terminal double-glycine peptidase domain. (731 aa)
secA-2Preprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. (798 aa)
rbsA-3ABC-type ribose transport system, ATPase component; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family. (496 aa)
nuoNNADH dehydrogenase subunit N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family. (500 aa)
nuoMNADH dehydrogenase subunit M. (503 aa)
nuoLNADH dehydrogenase subunit L. (618 aa)
nuoJNADH dehydrogenase subunit J; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (169 aa)
nuoCNADH dehydrogenase subunit C. (366 aa)
nuoBNADH dehydrogenase subunit B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (177 aa)
nuoANADH dehydrogenase subunit A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family. (132 aa)
atpDF0F1-type ATP synthase, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (473 aa)
atpAF0F1-type ATP synthase, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (507 aa)
ahpFAlkyl hydroperoxide reductase large subunit. (509 aa)
Aflv_2781Nucleoside permease; Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family. (434 aa)
sacPPhosphotransferase system (PTS) sucrose-specific enzyme IIBC component. (456 aa)
Your Current Organism:
Anoxybacillus flavithermus
NCBI taxonomy Id: 491915
Other names: A. flavithermus WK1, Anoxybacillus flavithermus WK1, Anoxybacillus flavithermus str. WK1, Anoxybacillus flavithermus strain WK1
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