STRINGSTRING
gcaD gcaD glmM glmM glmS glmS glgC glgC glgD glgD abfA abfA Aflv_0571 Aflv_0571 Aflv_0886 Aflv_0886 glcK glcK murB murB ptsG ptsG Aflv_2095 Aflv_2095 Aflv_2333 Aflv_2333 pgi pgi galE galE Aflv_2667 Aflv_2667 gtaB gtaB murAA murAA Aflv_2711 Aflv_2711 murAB murAB sacK sacK crr crr
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
gcaDUDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (468 aa)
glmMPhosphomannomutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. (447 aa)
glmSL-glutamine-D-fructose-6-phosphate amidotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (600 aa)
glgCGlucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (407 aa)
glgDADP-glucose pyrophosphorylase. (340 aa)
abfAAlpha-L-arabinofuranosidase. (502 aa)
Aflv_0571Nucleoside-diphosphate-sugar epimerase. (324 aa)
Aflv_0886Nucleoside-diphosphate-sugar pyrophosphorylase fused to phosphomannomutase. (815 aa)
glcKTranscriptional regulator/glucose kinase. (321 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (302 aa)
ptsGPhosphotransferase system (PTS) glucose-specific enzyme IICBA component. (663 aa)
Aflv_2095Predicted UDP-glucose 6-dehydrogenase. (421 aa)
Aflv_2333Phosphomannomutase. (588 aa)
pgiGlucose-6-phosphate isomerase; Belongs to the GPI family. (474 aa)
galEUDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (338 aa)
Aflv_2667UDP-glucose 6-dehydrogenase. (433 aa)
gtaBUTP-glucose-1-phosphate uridylyltransferase. (323 aa)
murAAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (439 aa)
Aflv_2711UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. (400 aa)
murABUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (438 aa)
sacKFructokinase (ribokinase family); Belongs to the carbohydrate kinase PfkB family. (321 aa)
crrPhosphotransferase system (PTS) sucrose-specific enzyme II A component. (160 aa)
Your Current Organism:
Anoxybacillus flavithermus
NCBI taxonomy Id: 491915
Other names: A. flavithermus WK1, Anoxybacillus flavithermus WK1, Anoxybacillus flavithermus str. WK1, Anoxybacillus flavithermus strain WK1
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.