node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Aflv_0474 | ackA | Aflv_0474 | Aflv_0480 | Acetyl-coenzyme A synthetase. | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | 0.926 |
Aflv_0474 | acsA | Aflv_0474 | Aflv_0462 | Acetyl-coenzyme A synthetase. | Acyl-coenzyme A synthetase. | 0.917 |
Aflv_0474 | pta | Aflv_0474 | Aflv_2760 | Acetyl-coenzyme A synthetase. | Phosphotransacetylase. | 0.916 |
ackA | Aflv_0474 | Aflv_0480 | Aflv_0474 | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | Acetyl-coenzyme A synthetase. | 0.926 |
ackA | acsA | Aflv_0480 | Aflv_0462 | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | Acyl-coenzyme A synthetase. | 0.926 |
ackA | pfkA | Aflv_0480 | Aflv_0499 | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. | 0.416 |
ackA | pta | Aflv_0480 | Aflv_2760 | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | Phosphotransacetylase. | 0.998 |
acsA | Aflv_0474 | Aflv_0462 | Aflv_0474 | Acyl-coenzyme A synthetase. | Acetyl-coenzyme A synthetase. | 0.917 |
acsA | ackA | Aflv_0462 | Aflv_0480 | Acyl-coenzyme A synthetase. | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | 0.926 |
acsA | pta | Aflv_0462 | Aflv_2760 | Acyl-coenzyme A synthetase. | Phosphotransacetylase. | 0.916 |
eno | fbaA | Aflv_2514 | Aflv_2729 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Fructose-1,6-bisphosphate aldolase. | 0.970 |
eno | glyA | Aflv_2514 | Aflv_2713 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Glycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.467 |
eno | mdh | Aflv_2514 | Aflv_0506 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.585 |
eno | pfkA | Aflv_2514 | Aflv_0499 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. | 0.864 |
eno | pgm | Aflv_2514 | Aflv_2515 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the BPG-independent phosphoglycerate mutase family. | 0.996 |
eno | serA | Aflv_2514 | Aflv_1055 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.456 |
fbaA | eno | Aflv_2729 | Aflv_2514 | Fructose-1,6-bisphosphate aldolase. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.970 |
fbaA | glpX | Aflv_2729 | Aflv_2726 | Fructose-1,6-bisphosphate aldolase. | Fructose-1,6-bisphosphatase (Class II). | 0.969 |
fbaA | glyA | Aflv_2729 | Aflv_2713 | Fructose-1,6-bisphosphate aldolase. | Glycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.469 |
fbaA | pfkA | Aflv_2729 | Aflv_0499 | Fructose-1,6-bisphosphate aldolase. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. | 0.964 |