STRINGSTRING
acpP_1 acpP_1 fabF fabF accD accD OSI13454.1 OSI13454.1 fabI fabI accB accB accC accC fabG_1 fabG_1 BWD07_03650 BWD07_03650 fabZ fabZ OSI12206.1 OSI12206.1 metN_2 metN_2 accA accA OSI12030.1 OSI12030.1 fabF2_3 fabF2_3 fabG-1_2 fabG-1_2 OSI12033.1 OSI12033.1 OSI12034.1 OSI12034.1 OSI12035.1 OSI12035.1 OSI12036.1 OSI12036.1 acpP_2 acpP_2 OSI12038.1 OSI12038.1 OSI12041.1 OSI12041.1 OSI12077.1 OSI12077.1 OSI12044.1 OSI12044.1 OSI12045.1 OSI12045.1 OSI12078.1 OSI12078.1 OSI12047.1 OSI12047.1 OSI12048.1 OSI12048.1 OSI12079.1 OSI12079.1 OSI12049.1 OSI12049.1 OSI12050.1 OSI12050.1 OSI12051.1 OSI12051.1 fabF2_2 fabF2_2 OSI12057.1 OSI12057.1 fabF2_1 fabF2_1 OSI12058.1 OSI12058.1 fabH fabH fabD fabD fabG fabG fabA fabA fabB fabB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
acpP_1Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (78 aa)
fabFBeta-ketoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (415 aa)
accDacetyl-CoA carboxylase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (289 aa)
OSI13454.1SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (362 aa)
fabIEnoyl-[acyl-carrier-protein] reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (260 aa)
accBacetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (151 aa)
accCacetyl-CoA carboxylase biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (452 aa)
fabG_13-oxoacyl-ACP reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (253 aa)
BWD07_03650Hypothetical protein; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (351 aa)
fabZ3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (152 aa)
OSI12206.1ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (416 aa)
metN_2ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (298 aa)
accAacetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (319 aa)
OSI12030.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the P-Pant transferase superfamily. (204 aa)
fabF2_3beta-ketoacyl-ACP synthase II; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (409 aa)
fabG-1_23-oxoacyl-ACP reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (242 aa)
OSI12033.1Thioester dehydrase; Derived by automated computational analysis using gene prediction method: Protein Homology. (162 aa)
OSI12034.13-oxoacyl-ACP synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (248 aa)
OSI12035.11-acyl-sn-glycerol-3-phosphate acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (252 aa)
OSI12036.1Acyl carrier protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (85 aa)
acpP_2Acyl carrier protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (81 aa)
OSI12038.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (179 aa)
OSI12041.1AMP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (571 aa)
OSI12077.1Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (240 aa)
OSI12044.1Glycosyl transferase family 2; Derived by automated computational analysis using gene prediction method: Protein Homology. (313 aa)
OSI12045.14-hydroxybenzoyl-CoA thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (145 aa)
OSI12078.1Hypothetical protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). (197 aa)
OSI12047.1Dialkylrecorsinol condensing enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. (302 aa)
OSI12048.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (387 aa)
OSI12079.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (147 aa)
OSI12049.1Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (332 aa)
OSI12050.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (797 aa)
OSI12051.1FAD-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (412 aa)
fabF2_2Beta-ketoacyl-[acyl-carrier-protein] synthase II; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (402 aa)
OSI12057.1Acyl carrier protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (96 aa)
fabF2_1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (348 aa)
OSI12058.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (243 aa)
fabH3-oxoacyl-ACP synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (319 aa)
fabD[acyl-carrier-protein] S-malonyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (308 aa)
fabG3-oxoacyl-ACP reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (248 aa)
fabA3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length. (174 aa)
fabBBeta-ketoacyl-[acyl-carrier-protein] synthase I; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (403 aa)
Your Current Organism:
Neisseria canis
NCBI taxonomy Id: 493
Other names: ATCC 14687, CIP 103347, LMG 8383, LMG:8383, N. canis, NCTC 10296, strain H 6
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.