(12 nodes) Signal transduction network (Neisseria canis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	OSI13356.1	RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (452 aa)
	rssB	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (223 aa)
	qseC	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (437 aa)
	OSI12657.1	Chemotaxis protein CheX; Derived by automated computational analysis using gene prediction method: Protein Homology. (152 aa)
	cheY	Response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (121 aa)
	frzE	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (723 aa)
	kinA	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (542 aa)
	zraR_1	Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (589 aa)
	ompR	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (225 aa)
	baeS	Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (464 aa)
	zraR_2	Sigma-54-dependent Fis family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (564 aa)
	OSI06652.1	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (129 aa)

Your Current Organism:

Neisseria canis

NCBI taxonomy Id: 493
Other names: ATCC 14687, CIP 103347, LMG 8383, LMG:8383, N. canis, NCTC 10296, strain H 6

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
OSI06652.1	baeS	BWD07_12395	BWD07_08400	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.981
OSI06652.1	cheY	BWD07_12395	BWD07_04245	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	Response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.809
OSI06652.1	frzE	BWD07_12395	BWD07_04250	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.634
OSI06652.1	kinA	BWD07_12395	BWD07_08210	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.870
OSI06652.1	qseC	BWD07_12395	BWD07_01060	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.917
OSI06652.1	zraR_1	BWD07_12395	BWD07_08215	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.417
OSI06652.1	zraR_2	BWD07_12395	BWD07_09870	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	Sigma-54-dependent Fis family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.714
OSI12657.1	cheY	BWD07_04240	BWD07_04245	Chemotaxis protein CheX; Derived by automated computational analysis using gene prediction method: Protein Homology.	Response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.937
OSI12657.1	frzE	BWD07_04240	BWD07_04250	Chemotaxis protein CheX; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.952
OSI12657.1	zraR_1	BWD07_04240	BWD07_08215	Chemotaxis protein CheX; Derived by automated computational analysis using gene prediction method: Protein Homology.	Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.403
OSI13356.1	baeS	BWD07_00120	BWD07_08400	RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.812
OSI13356.1	kinA	BWD07_00120	BWD07_08210	RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.933
OSI13356.1	qseC	BWD07_00120	BWD07_01060	RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.451
OSI13356.1	zraR_1	BWD07_00120	BWD07_08215	RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.982
OSI13356.1	zraR_2	BWD07_00120	BWD07_09870	RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	Sigma-54-dependent Fis family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.895
baeS	OSI06652.1	BWD07_08400	BWD07_12395	Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.981
baeS	OSI13356.1	BWD07_08400	BWD07_00120	Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	0.812
baeS	cheY	BWD07_08400	BWD07_04245	Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.876
baeS	frzE	BWD07_08400	BWD07_04250	Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.874
baeS	kinA	BWD07_08400	BWD07_08210	Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.982