(6 nodes) Mixed, incl. PAS domain, and NusB family network (Neisseria canis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ntrX	Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (433 aa)
	walK	PAS domain-containing sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (703 aa)
	OSI09904.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (200 aa)
	rsmB_1	16S rRNA (cytosine(967)-C(5))-methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. (420 aa)
	fmt	methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (307 aa)
	def	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (167 aa)

Your Current Organism:

Neisseria canis

NCBI taxonomy Id: 493
Other names: ATCC 14687, CIP 103347, LMG 8383, LMG:8383, N. canis, NCTC 10296, strain H 6

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
OSI09904.1	def	BWD07_11115	BWD07_11130	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	0.745
OSI09904.1	fmt	BWD07_11115	BWD07_11125	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.	0.809
OSI09904.1	ntrX	BWD07_11115	BWD07_11105	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.885
OSI09904.1	rsmB_1	BWD07_11115	BWD07_11120	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	16S rRNA (cytosine(967)-C(5))-methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.	0.825
OSI09904.1	walK	BWD07_11115	BWD07_11110	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	PAS domain-containing sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.917
def	OSI09904.1	BWD07_11130	BWD07_11115	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.745
def	fmt	BWD07_11130	BWD07_11125	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.	0.976
def	ntrX	BWD07_11130	BWD07_11105	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.740
def	rsmB_1	BWD07_11130	BWD07_11120	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	16S rRNA (cytosine(967)-C(5))-methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.	0.780
def	walK	BWD07_11130	BWD07_11110	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	PAS domain-containing sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.745
fmt	OSI09904.1	BWD07_11125	BWD07_11115	methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.809
fmt	def	BWD07_11125	BWD07_11130	methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	0.976
fmt	ntrX	BWD07_11125	BWD07_11105	methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.	Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.810
fmt	rsmB_1	BWD07_11125	BWD07_11120	methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.	16S rRNA (cytosine(967)-C(5))-methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.	0.945
fmt	walK	BWD07_11125	BWD07_11110	methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.	PAS domain-containing sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.809
ntrX	OSI09904.1	BWD07_11105	BWD07_11115	Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.885
ntrX	def	BWD07_11105	BWD07_11130	Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	0.740
ntrX	fmt	BWD07_11105	BWD07_11125	Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.	0.810
ntrX	rsmB_1	BWD07_11105	BWD07_11120	Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	16S rRNA (cytosine(967)-C(5))-methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.	0.815
ntrX	walK	BWD07_11105	BWD07_11110	Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	PAS domain-containing sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.980