(14 nodes) Mixed, incl. rRNA processing, and MafB19-like deaminase network (Neisseria canis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	rlmH	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. (156 aa)
	rsmE	16S rRNA (uracil(1498)-N(3))-methyltransferase; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. (242 aa)
	OSI13062.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (153 aa)
	prmA	Ribosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family. (295 aa)
	OSI12590.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (71 aa)
	rsmI_2	16S rRNA (cytidine(1402)-2'-O)-methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. (293 aa)
	OSI12592.1	YraN family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0102 family. (115 aa)
	glxK	Glycerate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycerate kinase type-1 family. (385 aa)
	OSI12513.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (73 aa)
	rlmL_2	SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the methyltransferase superfamily. (314 aa)
	OSI12515.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (376 aa)
	tadA	Cytidine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (239 aa)
	rluF	Pseudouridylate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pseudouridine synthase RsuA family. (247 aa)
	rlmL_1	RNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the methyltransferase superfamily. (380 aa)

Your Current Organism:

Neisseria canis

NCBI taxonomy Id: 493
Other names: ATCC 14687, CIP 103347, LMG 8383, LMG:8383, N. canis, NCTC 10296, strain H 6

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
OSI12513.1	OSI12515.1	BWD07_05260	BWD07_05270	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.468
OSI12513.1	glxK	BWD07_05260	BWD07_05255	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glycerate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycerate kinase type-1 family.	0.658
OSI12513.1	rlmL_2	BWD07_05260	BWD07_05265	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the methyltransferase superfamily.	0.694
OSI12515.1	OSI12513.1	BWD07_05270	BWD07_05260	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.468
OSI12515.1	glxK	BWD07_05270	BWD07_05255	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glycerate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycerate kinase type-1 family.	0.408
OSI12515.1	rlmL_2	BWD07_05270	BWD07_05265	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the methyltransferase superfamily.	0.516
OSI12590.1	rsmI_2	BWD07_04855	BWD07_04860	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	16S rRNA (cytidine(1402)-2'-O)-methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.	0.489
OSI12592.1	rsmI_2	BWD07_04865	BWD07_04860	YraN family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0102 family.	16S rRNA (cytidine(1402)-2'-O)-methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.	0.630
OSI13062.1	prmA	BWD07_01705	BWD07_01710	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Ribosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.	0.459
glxK	OSI12513.1	BWD07_05255	BWD07_05260	Glycerate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycerate kinase type-1 family.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.658
glxK	OSI12515.1	BWD07_05255	BWD07_05270	Glycerate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycerate kinase type-1 family.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.408
glxK	rlmL_2	BWD07_05255	BWD07_05265	Glycerate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycerate kinase type-1 family.	SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the methyltransferase superfamily.	0.592
glxK	tadA	BWD07_05255	BWD07_05995	Glycerate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycerate kinase type-1 family.	Cytidine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.	0.685
prmA	OSI13062.1	BWD07_01710	BWD07_01705	Ribosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.459
prmA	rlmH	BWD07_01710	BWD07_00700	Ribosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.	0.491
prmA	rsmE	BWD07_01710	BWD07_00840	Ribosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.	16S rRNA (uracil(1498)-N(3))-methyltransferase; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.	0.738
rlmH	prmA	BWD07_00700	BWD07_01710	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.	Ribosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.	0.491
rlmL_1	rlmL_2	BWD07_10925	BWD07_05265	RNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the methyltransferase superfamily.	SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the methyltransferase superfamily.	0.956
rlmL_1	rluF	BWD07_10925	BWD07_10920	RNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the methyltransferase superfamily.	Pseudouridylate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pseudouridine synthase RsuA family.	0.793
rlmL_2	OSI12513.1	BWD07_05265	BWD07_05260	SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the methyltransferase superfamily.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.694