(19 nodes) Sulfur metabolism, and Polyamine transport network (Neisseria canis)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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protein homology

Your Input:
	potF_1	Hypothetical protein; Required for the activity of the bacterial periplasmic transport system of putrescine; Belongs to the bacterial solute-binding protein PotD/PotF family. (391 aa)
	potF_2	Polyamine ABC transporter substrate-binding protein; Required for the activity of the bacterial periplasmic transport system of putrescine; Belongs to the bacterial solute-binding protein PotD/PotF family. (380 aa)
	sbp	Sulfate ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (345 aa)
	cysA	Sulfate ABC transporter ATP-binding protein; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Sulfate/tungstate importer (TC 3.A.1.6) family. (360 aa)
	cysW	Sulfate ABC transporter permease subunit CysW; Derived by automated computational analysis using gene prediction method: Protein Homology. (283 aa)
	cysU_1	Sulfate ABC transporter permease subunit CysT; Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (275 aa)
	fbpC_3	Fe3+/spermidine/putrescine ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily. (342 aa)
	fbpB	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (537 aa)
	OSI12505.1	Fe(3+) ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (330 aa)
	ycbX_2	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (275 aa)
	potA	Polyamine ABC transporter ATP-binding protein; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system. (372 aa)
	potH	Putrescine/spermidine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (322 aa)
	ydcV	Polyamine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (297 aa)
	cysJ	Sulfite reductase [NADPH] flavoprotein, alpha-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. (591 aa)
	cysN	Sulfate adenylyltransferase; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (436 aa)
	cysI	Sulfite reductase subunit beta; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (588 aa)
	cysD	Sulfate adenylyltransferase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (306 aa)
	cysH	Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. (243 aa)
	potD-1	Polyamine ABC transporter substrate-binding protein; Required for the activity of the bacterial periplasmic transport system of putrescine; Belongs to the bacterial solute-binding protein PotD/PotF family. (380 aa)

Your Current Organism:

Neisseria canis

NCBI taxonomy Id: 493
Other names: ATCC 14687, CIP 103347, LMG 8383, LMG:8383, N. canis, NCTC 10296, strain H 6

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
OSI12505.1	cysU_1	BWD07_05220	BWD07_03100	Fe(3+) ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Sulfate ABC transporter permease subunit CysT; Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.	0.468
OSI12505.1	fbpB	BWD07_05220	BWD07_05215	Fe(3+) ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.997
OSI12505.1	fbpC_3	BWD07_05220	BWD07_05210	Fe(3+) ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Fe3+/spermidine/putrescine ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.	0.987
OSI12505.1	potA	BWD07_05220	BWD07_08560	Fe(3+) ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Polyamine ABC transporter ATP-binding protein; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.	0.562
OSI12505.1	potH	BWD07_05220	BWD07_08565	Fe(3+) ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Putrescine/spermidine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.468
OSI12505.1	sbp	BWD07_05220	BWD07_03085	Fe(3+) ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Sulfate ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.468
OSI12505.1	ydcV	BWD07_05220	BWD07_08570	Fe(3+) ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Polyamine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.468
cysA	cysD	BWD07_03090	BWD07_09300	Sulfate ABC transporter ATP-binding protein; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Sulfate/tungstate importer (TC 3.A.1.6) family.	Sulfate adenylyltransferase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.978
cysA	cysH	BWD07_03090	BWD07_09305	Sulfate ABC transporter ATP-binding protein; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Sulfate/tungstate importer (TC 3.A.1.6) family.	Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.	0.793
cysA	cysI	BWD07_03090	BWD07_09295	Sulfate ABC transporter ATP-binding protein; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Sulfate/tungstate importer (TC 3.A.1.6) family.	Sulfite reductase subunit beta; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.	0.727
cysA	cysJ	BWD07_03090	BWD07_09285	Sulfate ABC transporter ATP-binding protein; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Sulfate/tungstate importer (TC 3.A.1.6) family.	Sulfite reductase [NADPH] flavoprotein, alpha-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.	0.699
cysA	cysN	BWD07_03090	BWD07_09290	Sulfate ABC transporter ATP-binding protein; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Sulfate/tungstate importer (TC 3.A.1.6) family.	Sulfate adenylyltransferase; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.	0.981
cysA	cysU_1	BWD07_03090	BWD07_03100	Sulfate ABC transporter ATP-binding protein; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Sulfate/tungstate importer (TC 3.A.1.6) family.	Sulfate ABC transporter permease subunit CysT; Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.	0.999
cysA	cysW	BWD07_03090	BWD07_03095	Sulfate ABC transporter ATP-binding protein; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Sulfate/tungstate importer (TC 3.A.1.6) family.	Sulfate ABC transporter permease subunit CysW; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
cysA	fbpB	BWD07_03090	BWD07_05215	Sulfate ABC transporter ATP-binding protein; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Sulfate/tungstate importer (TC 3.A.1.6) family.	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.416
cysA	fbpC_3	BWD07_03090	BWD07_05210	Sulfate ABC transporter ATP-binding protein; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Sulfate/tungstate importer (TC 3.A.1.6) family.	Fe3+/spermidine/putrescine ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.	0.600
cysA	potA	BWD07_03090	BWD07_08560	Sulfate ABC transporter ATP-binding protein; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Sulfate/tungstate importer (TC 3.A.1.6) family.	Polyamine ABC transporter ATP-binding protein; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.	0.585
cysA	potH	BWD07_03090	BWD07_08565	Sulfate ABC transporter ATP-binding protein; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Sulfate/tungstate importer (TC 3.A.1.6) family.	Putrescine/spermidine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.492
cysA	sbp	BWD07_03090	BWD07_03085	Sulfate ABC transporter ATP-binding protein; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Sulfate/tungstate importer (TC 3.A.1.6) family.	Sulfate ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
cysA	ydcV	BWD07_03090	BWD07_08570	Sulfate ABC transporter ATP-binding protein; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Sulfate/tungstate importer (TC 3.A.1.6) family.	Polyamine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.531