STRINGSTRING
mlaD mlaD OSI12454.1 OSI12454.1 trxB trxB brfA brfA bfr bfr secA secA porB_1 porB_1 emrB emrB msbA msbA OSI12323.1 OSI12323.1 secF secF secD secD yfkJ yfkJ tpx tpx OSI12008.1 OSI12008.1 resA resA ampG ampG OSI11800.1 OSI11800.1 porB_2 porB_2 bcp bcp lrp1_2 lrp1_2 luxA luxA yajR yajR yjbI yjbI sodB_2 sodB_2 fbp_1 fbp_1 OSI11046.1 OSI11046.1 sucB sucB bcr bcr OSI10317.1 OSI10317.1 OSI09915.1 OSI09915.1 BWD07_11600 BWD07_11600 tufA_2 tufA_2 OSI06669.1 OSI06669.1 OSI06643.1 OSI06643.1 OSI06634.1 OSI06634.1 OSI06630.1 OSI06630.1 OSI13371.1 OSI13371.1 lrp lrp lrp1_1 lrp1_1 sodB_1 sodB_1 sodC sodC rpoZ rpoZ ribD ribD etp etp secG secG OSI13119.1 OSI13119.1 ynfM ynfM rpoA rpoA secY secY OSI13016.1 OSI13016.1 ndk ndk OSI12897.1 OSI12897.1 OSI12915.1 OSI12915.1 lplT lplT gsiA gsiA trxA trxA aceF aceF ftnA ftnA OSI12533.1 OSI12533.1 fkpA fkpA hsrA hsrA rpoC rpoC rpoB rpoB secE secE
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
mlaDOuter membrane lipid asymmetry maintenance protein MlaD; Derived by automated computational analysis using gene prediction method: Protein Homology. (170 aa)
OSI12454.1Elongation factor Tu; Derived by automated computational analysis using gene prediction method: Protein Homology. (91 aa)
trxBThioredoxin-disulfide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (317 aa)
brfABacterioferritin; Iron-storage protein. (154 aa)
bfrBacterioferritin; Iron-storage protein. (157 aa)
secAPreprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family. (921 aa)
porB_1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (102 aa)
emrBMFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (440 aa)
msbALipid A export permease/ATP-binding protein MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. (616 aa)
OSI12323.1Elongation factor Tu; Derived by automated computational analysis using gene prediction method: Protein Homology. (42 aa)
secFProtein-export membrane protein SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (311 aa)
secDProtein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (621 aa)
yfkJProtein-tyrosine-phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. (156 aa)
tpxLipid hydroperoxide peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily. (165 aa)
OSI12008.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (120 aa)
resAThioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (162 aa)
ampGMFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (510 aa)
OSI11800.1Glutamate--cysteine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (448 aa)
porB_2Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (361 aa)
bcpPeroxiredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (144 aa)
lrp1_2AsnC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (154 aa)
luxALuciferase family oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (335 aa)
yajRHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (460 aa)
yjbIGlobin; Derived by automated computational analysis using gene prediction method: Protein Homology. (165 aa)
sodB_2Hypothetical protein; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (193 aa)
fbp_1Peptidylprolyl isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (108 aa)
OSI11046.1Multidrug ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (620 aa)
sucBDihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (396 aa)
bcrBcr/CflA family drug resistance efflux transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (405 aa)
OSI10317.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (470 aa)
OSI09915.1Elongation factor Tu; Derived by automated computational analysis using gene prediction method: Protein Homology. (42 aa)
BWD07_116002OG-Fe(II) oxygenase; Internal stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (468 aa)
tufA_2Translation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (344 aa)
OSI06669.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (138 aa)
OSI06643.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (80 aa)
OSI06634.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (114 aa)
OSI06630.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (84 aa)
OSI13371.1Protein disulfide oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (170 aa)
lrpTranscriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (154 aa)
lrp1_1ArsR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (161 aa)
sodB_1Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (207 aa)
sodCSuperoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (174 aa)
rpoZDNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (68 aa)
ribDRiboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (368 aa)
etpPhosphotyrosine protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. (144 aa)
secGPreprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. (115 aa)
OSI13119.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (492 aa)
ynfMMFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (386 aa)
rpoADNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (327 aa)
secYPreprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. (430 aa)
OSI13016.1Alkylhydroperoxidase; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. (180 aa)
ndkNucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (141 aa)
OSI12897.1MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (533 aa)
OSI12915.1Thiol reductase thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (176 aa)
lplTHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (435 aa)
gsiAMicrocin ABC transporter ATP-binding protein; With YejAEF is involved in resistance to microcin C; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily. (513 aa)
trxAThiol reductase thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thioredoxin family. (109 aa)
aceFDihydrolipoyllysine-residue acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (545 aa)
ftnAFerritin; Iron-storage protein. (164 aa)
OSI12533.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (476 aa)
fkpAHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (208 aa)
hsrAHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (228 aa)
rpoCDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1392 aa)
rpoBDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1392 aa)
secEPreprotein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family. (160 aa)
Your Current Organism:
Neisseria canis
NCBI taxonomy Id: 493
Other names: ATCC 14687, CIP 103347, LMG 8383, LMG:8383, N. canis, NCTC 10296, strain H 6
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