STRINGSTRING
YDR034W-B YDR034W-B YGL217C YGL217C SCM4 SCM4 YHR069C-A YHR069C-A YIL134C-A YIL134C-A YJL133C-A YJL133C-A YJL136W-A YJL136W-A YJL197C-A YJL197C-A YJR038C YJR038C BUD28 BUD28 YLR124W YLR124W YLR125W YLR125W YLR126C YLR126C YMR182W-A YMR182W-A GTO3 GTO3 YOL024W YOL024W MAM3 MAM3 YOR073W-A YOR073W-A MRX4 MRX4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
YDR034W-BCysteine-rich and transmembrane domain-containing protein YDR034W-B; Predicted tail-anchored plasma membrane protein; contains conserved CYSTM module; related proteins in other organisms may be involved in response to stress; N- and C-terminal fusion proteins localize to the cell periphery; YDR034W-B has a paralog, YBR056W-A, that arose from the whole genome duplication; Belongs to the CYSTM1 family. (51 aa)
YGL217CPutative uncharacterized protein YGL217C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF KIP3/YGL216W. (113 aa)
SCM4Protein SCM4; Mitochondrial outer membrane protein of unknown function; predicted to have 4 transmembrane segments; import is mediated by Tom70p and Mim1p; interacts genetically with a cdc4 mutation; SCM4 has a paralog, ATG33, that arose from the whole genome duplication. (187 aa)
YHR069C-APutative uncharacterized membrane protein YHR069C-A; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; completely overlaps ORF TRM5/YHR070W. (120 aa)
YIL134C-AUncharacterized protein YIL134C-A; Putative protein of unknown function; identified by fungal homology and RT-PCR. (67 aa)
YJL133C-AUncharacterized protein YJL133C-A; Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies. (74 aa)
YJL136W-AUncharacterized protein YJL136W-A; Putative protein of unknown function; identified by SAGE. (27 aa)
YJL197C-AUncharacterized protein YJL197C-A; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; completely overlaps the verified gene YJL197C/UBP12. (93 aa)
YJR038CPutative uncharacterized protein YJR038C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data. (120 aa)
BUD28Putative uncharacterized protein BUD28; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; not conserved in closely related Saccharomyces species; 98% of ORF overlaps the verified gene RPL22A; diploid mutant displays a weak budding pattern phenotype in a systematic assay. (125 aa)
YLR124WPutative uncharacterized protein YLR124W; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data. (114 aa)
YLR125WPutative protein of unknown function; mutant has decreased Ty3 transposition; YLR125W is not an essential gene. (136 aa)
YLR126CPutative glutamine amidotransferase; has Aft1p-binding motif in the promoter; may be involved in copper and iron homeostasis; YLR126C is not an essential protein; relocalizes from nucleus to cytoplasmic foci upon DNA replication stress. (251 aa)
YMR182W-AUncharacterized protein YMR182W-A; Putative protein of unknown function. (28 aa)
GTO3Glutathione S-transferase omega-like 3; Omega class glutathione transferase; putative cytosolic localization. (366 aa)
YOL024WPutative protein of unknown function; predicted to have thiol-disulfide oxidoreductase active site; YOL024W has a paralog, IGD1, that arose from the whole genome duplication. (172 aa)
MAM3Protein required for normal mitochondrial morphology; has similarity to hemolysins. (706 aa)
YOR073W-APutative uncharacterized protein YOR073W-A; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially/completely overlaps the verified ORF CDC21/YOR074C; identified by RT-PCR. (77 aa)
MRX4MIOREX complex component 4; Protein that associates with mitochondrial ribosome; green fluorescent protein (GFP)-fusion protein localizes to the mitochondrion; expression may be cell cycle-regulated. (430 aa)
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: ATCC 18824, Candida robusta, Mycoderma cerevisiae, NRRL Y-12632, S. cerevisiae, Saccharomyces capensis, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, yeast
Server load: low (32%) [HD]