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MRPL16 MRPL16 MRPS9 MRPS9 MRPL27 MRPL27 MRPL32 MRPL32 IMG1 IMG1 IMG2 IMG2 MRX14 MRX14 MRPL7 MRPL7 MRPS28 MRPS28 MRP20 MRP20 MRPL28 MRPL28 RML2 RML2 MNP1 MNP1 MRPL9 MRPL9 MRPL6 MRPL6 MRPL8 MRPL8 MRPL38 MRPL38 MRPL4 MRPL4 MRPL39 MRPL39 YML6 YML6 MRPL3 MRPL3 MRPL24 MRPL24 MRPL33 MRPL33 MRP7 MRP7 MRPL22 MRPL22 MRPL17 MRPL17 MRPL10 MRPL10 MRPL23 MRPL23 MRPS16 MRPS16 RTC6 RTC6 MRPL51 MRPL51
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MRPL16Mitochondrial ribosomal protein of the large subunit; homologous to bacterial L16 ribosomal protein; synthetic lethality with hac1 mutation suggests a possible role in synthesis of precursors for protein glycosylation. (232 aa)
MRPS9Mitochondrial ribosomal protein of the small subunit. (278 aa)
MRPL27Mitochondrial ribosomal protein of the large subunit; homolog of human Bcl-2 interacting protein BMRP. (146 aa)
MRPL32Mitochondrial ribosomal protein of the large subunit; protein abundance increases in response to DNA replication stress. (183 aa)
IMG1Mitochondrial ribosomal protein of the large subunit; required for respiration and for maintenance of the mitochondrial genome. (169 aa)
IMG2Mitochondrial ribosomal protein of the large subunit; conserved in metazoa, with similarity to human mitochondrial ribosomal protein MRPL49. (146 aa)
MRX14Putative mitochondrial ribosomal protein of the large subunit; similar to E. coli L34 ribosomal protein; required for respiratory growth, as are most mitochondrial ribosomal proteins; protein increases in abundance and relocalizes to the plasma membrane upon DNA replication stress. (105 aa)
MRPL7Mitochondrial ribosomal protein of the large subunit; MRPL7 produces both YmL5 and YmL7, which are two different modified forms of the same protein. (292 aa)
MRPS28Mitochondrial ribosomal protein of the small subunit. (286 aa)
MRP20Mitochondrial ribosomal protein of the large subunit. (263 aa)
MRPL28Mitochondrial ribosomal protein of the large subunit; protein abundance increases in response to DNA replication stress. (147 aa)
RML2Mitochondrial ribosomal protein of the large subunit (L2); has similarity to E. coli L2 ribosomal protein; mutant allele (fat21) causes inability to utilize oleate, and induce oleic acid oxidation; may interfere with activity of the Adr1p transcription factor. (393 aa)
MNP1Mitochondrial ribosomal protein of the large subunit; has similarity to E. coli L7/L12 and human MRPL7 ribosomal proteins; associates with the mitochondrial nucleoid; required for normal respiratory growth. (194 aa)
MRPL9Mitochondrial ribosomal protein of the large subunit. (269 aa)
MRPL6Mitochondrial ribosomal protein of the large subunit. (214 aa)
MRPL8Mitochondrial ribosomal protein of the large subunit. (238 aa)
MRPL38Mitochondrial ribosomal protein of the large subunit; appears as two protein spots (YmL34 and YmL38) on two-dimensional SDS gels; protein abundance increases in response to DNA replication stress. (138 aa)
MRPL4Mitochondrial ribosomal protein of the large subunit; homolog of prokaryotic L29 ribosomal protein; located at the ribosomal tunnel exit. (319 aa)
MRPL39Mitochondrial ribosomal protein of the large subunit. (70 aa)
YML6Mitochondrial ribosomal protein of the large subunit; has similarity to E. coli L4 ribosomal protein and human mitoribosomal MRP-L4 protein; essential for viability, unlike most other mitoribosomal proteins. (286 aa)
MRPL3Mitochondrial ribosomal protein of the large subunit; located in close proximity to the polypeptide exit channel of the ribosome; mutations in human homolog MRPL44 cause childhood cardiomyopathy; human MRPL44 deficiency results in inefficient assembly of the mitochondrial ribosome, and in tissue-specific respiratory chain deficiency, manifesting as either Complex I+Complex IV or Complex IV deficiency, depending on a cell type; Belongs to the ribonuclease III family. Mitochondrion- specific ribosomal protein mL44 subfamily. (390 aa)
MRPL24Mitochondrial ribosomal protein of the large subunit; two mitochondrial ribosomal proteins, YmL14 and YmL24, have been assigned to the same gene. (258 aa)
MRPL33Mitochondrial ribosomal protein of the large subunit. (86 aa)
MRP7Mitochondrial ribosomal protein of the large subunit. (371 aa)
MRPL22Mitochondrial ribosomal protein of the large subunit. (309 aa)
MRPL17Mitochondrial ribosomal protein of the large subunit. (281 aa)
MRPL10Mitochondrial ribosomal protein of the large subunit; appears as two protein spots (YmL10 and YmL18) on two-dimensional SDS gels. (322 aa)
MRPL23Mitochondrial ribosomal protein of the large subunit; localizes to vacuole in response to H2O2. (163 aa)
MRPS16Mitochondrial ribosomal protein of the small subunit. (121 aa)
RTC654S ribosomal protein RTC6, mitochondrial; Protein involved in translation; mutants have defects in biogenesis of nuclear ribosomes; sequence similar to prokaryotic ribosomal protein L36, may be a mitochondrial ribosomal protein; protein abundance increases in response to DNA replication stress; Belongs to the bacterial ribosomal protein bL36 family. (93 aa)
MRPL51Mitochondrial ribosomal protein of the large subunit. (140 aa)
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: ATCC 18824, Candida robusta, Mycoderma cerevisiae, NRRL Y-12632, S. cerevisiae, Saccharomyces capensis, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, yeast
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