node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AMF1 | GEX1 | YOR378W | YCL073C | Low affinity NH4+ transporter; member of the DHA2 family of drug:H+ anti porters; putative paralog of ATR1; but not required for boron tolerance; non-essential gene; Belongs to the major facilitator superfamily. | Glutathione exchanger 1; Proton:glutathione antiporter; localized to the vacuolar and plasma membranes; imports glutathione from the vacuole and exports it through the plasma membrane; has a role in resistance to oxidative stress and modulation of the PKA pathway; GEX1 has a paralog, GEX2, that arose from a segmental duplication. | 0.540 |
AMF1 | VBA2 | YOR378W | YBR293W | Low affinity NH4+ transporter; member of the DHA2 family of drug:H+ anti porters; putative paralog of ATR1; but not required for boron tolerance; non-essential gene; Belongs to the major facilitator superfamily. | Permease of basic amino acids in the vacuolar membrane; Belongs to the major facilitator superfamily. | 0.749 |
AMF1 | VBA4 | YOR378W | YDR119W | Low affinity NH4+ transporter; member of the DHA2 family of drug:H+ anti porters; putative paralog of ATR1; but not required for boron tolerance; non-essential gene; Belongs to the major facilitator superfamily. | Protein of unknown function; proposed role as a basic amino acid permease based on phylogeny; GFP-fusion protein localizes to vacuolar membrane; physical interaction with Atg27p suggests a possible role in autophagy; non-essential gene; Belongs to the major facilitator superfamily. | 0.702 |
GEX1 | AMF1 | YCL073C | YOR378W | Glutathione exchanger 1; Proton:glutathione antiporter; localized to the vacuolar and plasma membranes; imports glutathione from the vacuole and exports it through the plasma membrane; has a role in resistance to oxidative stress and modulation of the PKA pathway; GEX1 has a paralog, GEX2, that arose from a segmental duplication. | Low affinity NH4+ transporter; member of the DHA2 family of drug:H+ anti porters; putative paralog of ATR1; but not required for boron tolerance; non-essential gene; Belongs to the major facilitator superfamily. | 0.540 |
GEX1 | VBA2 | YCL073C | YBR293W | Glutathione exchanger 1; Proton:glutathione antiporter; localized to the vacuolar and plasma membranes; imports glutathione from the vacuole and exports it through the plasma membrane; has a role in resistance to oxidative stress and modulation of the PKA pathway; GEX1 has a paralog, GEX2, that arose from a segmental duplication. | Permease of basic amino acids in the vacuolar membrane; Belongs to the major facilitator superfamily. | 0.479 |
GEX1 | VBA4 | YCL073C | YDR119W | Glutathione exchanger 1; Proton:glutathione antiporter; localized to the vacuolar and plasma membranes; imports glutathione from the vacuole and exports it through the plasma membrane; has a role in resistance to oxidative stress and modulation of the PKA pathway; GEX1 has a paralog, GEX2, that arose from a segmental duplication. | Protein of unknown function; proposed role as a basic amino acid permease based on phylogeny; GFP-fusion protein localizes to vacuolar membrane; physical interaction with Atg27p suggests a possible role in autophagy; non-essential gene; Belongs to the major facilitator superfamily. | 0.517 |
VBA2 | AMF1 | YBR293W | YOR378W | Permease of basic amino acids in the vacuolar membrane; Belongs to the major facilitator superfamily. | Low affinity NH4+ transporter; member of the DHA2 family of drug:H+ anti porters; putative paralog of ATR1; but not required for boron tolerance; non-essential gene; Belongs to the major facilitator superfamily. | 0.749 |
VBA2 | GEX1 | YBR293W | YCL073C | Permease of basic amino acids in the vacuolar membrane; Belongs to the major facilitator superfamily. | Glutathione exchanger 1; Proton:glutathione antiporter; localized to the vacuolar and plasma membranes; imports glutathione from the vacuole and exports it through the plasma membrane; has a role in resistance to oxidative stress and modulation of the PKA pathway; GEX1 has a paralog, GEX2, that arose from a segmental duplication. | 0.479 |
VBA2 | VBA4 | YBR293W | YDR119W | Permease of basic amino acids in the vacuolar membrane; Belongs to the major facilitator superfamily. | Protein of unknown function; proposed role as a basic amino acid permease based on phylogeny; GFP-fusion protein localizes to vacuolar membrane; physical interaction with Atg27p suggests a possible role in autophagy; non-essential gene; Belongs to the major facilitator superfamily. | 0.698 |
VBA2 | YJL163C | YBR293W | YJL163C | Permease of basic amino acids in the vacuolar membrane; Belongs to the major facilitator superfamily. | Uncharacterized membrane protein YJL163C; Putative protein of unknown function. | 0.791 |
VBA2 | YMR155W | YBR293W | YMR155W | Permease of basic amino acids in the vacuolar membrane; Belongs to the major facilitator superfamily. | Uncharacterized membrane protein YMR155W; Putative protein of unknown function; identified as interacting with Hsp82p in a high-throughput two-hybrid screen. | 0.616 |
VBA4 | AMF1 | YDR119W | YOR378W | Protein of unknown function; proposed role as a basic amino acid permease based on phylogeny; GFP-fusion protein localizes to vacuolar membrane; physical interaction with Atg27p suggests a possible role in autophagy; non-essential gene; Belongs to the major facilitator superfamily. | Low affinity NH4+ transporter; member of the DHA2 family of drug:H+ anti porters; putative paralog of ATR1; but not required for boron tolerance; non-essential gene; Belongs to the major facilitator superfamily. | 0.702 |
VBA4 | GEX1 | YDR119W | YCL073C | Protein of unknown function; proposed role as a basic amino acid permease based on phylogeny; GFP-fusion protein localizes to vacuolar membrane; physical interaction with Atg27p suggests a possible role in autophagy; non-essential gene; Belongs to the major facilitator superfamily. | Glutathione exchanger 1; Proton:glutathione antiporter; localized to the vacuolar and plasma membranes; imports glutathione from the vacuole and exports it through the plasma membrane; has a role in resistance to oxidative stress and modulation of the PKA pathway; GEX1 has a paralog, GEX2, that arose from a segmental duplication. | 0.517 |
VBA4 | VBA2 | YDR119W | YBR293W | Protein of unknown function; proposed role as a basic amino acid permease based on phylogeny; GFP-fusion protein localizes to vacuolar membrane; physical interaction with Atg27p suggests a possible role in autophagy; non-essential gene; Belongs to the major facilitator superfamily. | Permease of basic amino acids in the vacuolar membrane; Belongs to the major facilitator superfamily. | 0.698 |
VBA4 | YMR155W | YDR119W | YMR155W | Protein of unknown function; proposed role as a basic amino acid permease based on phylogeny; GFP-fusion protein localizes to vacuolar membrane; physical interaction with Atg27p suggests a possible role in autophagy; non-essential gene; Belongs to the major facilitator superfamily. | Uncharacterized membrane protein YMR155W; Putative protein of unknown function; identified as interacting with Hsp82p in a high-throughput two-hybrid screen. | 0.456 |
YJL163C | VBA2 | YJL163C | YBR293W | Uncharacterized membrane protein YJL163C; Putative protein of unknown function. | Permease of basic amino acids in the vacuolar membrane; Belongs to the major facilitator superfamily. | 0.791 |
YJL163C | YMR155W | YJL163C | YMR155W | Uncharacterized membrane protein YJL163C; Putative protein of unknown function. | Uncharacterized membrane protein YMR155W; Putative protein of unknown function; identified as interacting with Hsp82p in a high-throughput two-hybrid screen. | 0.920 |
YMR155W | VBA2 | YMR155W | YBR293W | Uncharacterized membrane protein YMR155W; Putative protein of unknown function; identified as interacting with Hsp82p in a high-throughput two-hybrid screen. | Permease of basic amino acids in the vacuolar membrane; Belongs to the major facilitator superfamily. | 0.616 |
YMR155W | VBA4 | YMR155W | YDR119W | Uncharacterized membrane protein YMR155W; Putative protein of unknown function; identified as interacting with Hsp82p in a high-throughput two-hybrid screen. | Protein of unknown function; proposed role as a basic amino acid permease based on phylogeny; GFP-fusion protein localizes to vacuolar membrane; physical interaction with Atg27p suggests a possible role in autophagy; non-essential gene; Belongs to the major facilitator superfamily. | 0.456 |
YMR155W | YJL163C | YMR155W | YJL163C | Uncharacterized membrane protein YMR155W; Putative protein of unknown function; identified as interacting with Hsp82p in a high-throughput two-hybrid screen. | Uncharacterized membrane protein YJL163C; Putative protein of unknown function. | 0.920 |