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NCW2 | Cell wall biogenesis protein NCW2; Structural constituent of the cell wall; attached to the plasma membrane by a GPI-anchor; expression is upregulated in response to cell wall stress; null mutant is sensitive to the antifungal agent polyhexamethylene biguanide, resistant to zymolyase treatment and has increased chitin deposition. (254 aa) | ||||
PAU22 | Protein of unknown function; member of the seripauperin multigene family encoded mainly in subtelomeric regions; SWAT-GFP fusion protein localizes to the endoplasmic reticulum and vacuole, while mCherry fusion localizes to just the vacuole; identical to Pau21p; encodes two proteins that are translated from two different start codons. (164 aa) | ||||
PAU21 | Seripauperin-21; Protein of unknown function; member of the seripauperin multigene family encoded mainly in subtelomeric regions; SWAT-GFP, seamless-GFP and mCherry fusion proteins localize to the cytosol; identical to Pau22p; encodes two proteins that are translated from 2 different start codons; Belongs to the SRP1/TIP1 family. Seripauperin subfamily. (164 aa) | ||||
TIR2 | Cold shock-induced protein TIR2; Putative cell wall mannoprotein; member of the Srp1p/Tip1p family of serine-alanine-rich proteins; transcription is induced by cold shock and anaerobiosis; TIR2 has a paralog, TIR3, that arose from the whole genome duplication. (251 aa) | ||||
TIR4 | Cell wall mannoprotein; expressed under anaerobic conditions and required for anaerobic growth; transcription is also induced by cold shock; member of the Srp1p/Tip1p family of serine-alanine-rich proteins. (487 aa) | ||||
PAU20 | Seripauperin-20; Protein of unknown function; member of the seripauperin multigene family encoded mainly in subtelomeric regions; SWAT-GFP and mCherry fusion proteins localize to the vacuole; expression induced by low temperature and also by anaerobic conditions; induced during alcoholic fermentation. (120 aa) | ||||
PAU6 | Member of the seripauperin multigene family; encoded mainly in subtelomeric regions; SWAT-GFP fusion protein localizes to the endoplasmic reticulum and vacuole, while mCherry fusion localizes to just the vacuole; active during alcoholic fermentation; regulated by anaerobiosis; negatively regulated by oxygen; repressed by heme; identical to Pau18p. (120 aa) | ||||
KRE1 | Cell wall glycoprotein involved in beta-glucan assembly; serves as a K1 killer toxin membrane receptor. (313 aa) | ||||
PAU19 | Protein of unknown function; member of the seripauperin multigene family encoded mainly in subtelomeric regions. (124 aa) | ||||
PAU8 | Seripauperin-11; Protein of unknown function; member of the seripauperin multigene family encoded mainly in subtelomeric regions; Belongs to the SRP1/TIP1 family. Seripauperin subfamily. (120 aa) | ||||
PAU7 | Seripauperin-7; Member of the seripauperin multigene family; active during alcoholic fermentation, regulated by anaerobiosis, inhibited by oxygen, repressed by heme; Belongs to the SRP1/TIP1 family. Seripauperin subfamily. (55 aa) | ||||
PAU9 | Protein of unknown function; member of the seripauperin multigene family encoded mainly in subtelomeric regions; SWAT-GFP and mCherry fusion proteins localize to the endoplasmic reticulum and vacuole respectively. (42 aa) | ||||
TIP1 | Temperature shock-inducible protein 1; Major cell wall mannoprotein with possible lipase activity; transcription is induced by heat- and cold-shock; member of the Srp1p/Tip1p family of serine-alanine-rich proteins. (210 aa) | ||||
PAU24 | Seripauperin-24; Cell wall mannoprotein; has similarity to Tir1p, Tir2p, Tir3p, and Tir4p; member of the seripauperin multigene family encoded mainly in subtelomeric regions; expressed under anaerobic conditions, completely repressed during aerobic growth; Belongs to the SRP1/TIP1 family. Seripauperin subfamily. (120 aa) | ||||
PAU3 | Seripauperin-3; Member of the seripauperin multigene family; encoded mainly in subtelomeric region; active during alcoholic fermentation; regulated by anaerobiosis; negatively regulated by oxygen; repressed by heme. (124 aa) | ||||
SED1 | Cell wall protein SED1; Major stress-induced structural GPI-cell wall glycoprotein; associates with translating ribosomes, possible role in mitochondrial genome maintenance; ORF contains two distinct variable minisatellites; SED1 has a paralog, SPI1, that arose from the whole genome duplication. (338 aa) | ||||
PAU10 | Seripauperin-10; Protein of unknown function; SWAT-GFP fusion protein localizes to the endoplasmic reticulum and vacuole, while mCherry fusion localizes to the vacuole; member of the seripauperin multigene family encoded mainly in subtelomeric regions; Belongs to the SRP1/TIP1 family. Seripauperin subfamily. (120 aa) | ||||
PAU2 | Seripauperin-2; Member of the seripauperin multigene family; encoded mainly in subtelomeric region; active during alcoholic fermentation; regulated by anaerobiosis; negatively regulated by oxygen; repressed by heme. (120 aa) | ||||
TIR1 | Cold shock-induced protein TIR1; Cell wall mannoprotein; expression is downregulated at acidic pH and induced by cold shock and anaerobiosis; abundance is increased in cells cultured without shaking; member of the Srp1p/Tip1p family of serine-alanine-rich proteins; Belongs to the SRP1/TIP1 family. (254 aa) | ||||
SPI1 | GPI-anchored cell wall protein involved in weak acid resistance; basal expression requires Msn2p/Msn4p; expression is induced under conditions of stress and during the diauxic shift; SPI1 has a paralog, SED1, that arose from the whole genome duplication; Belongs to the SED1 family. (148 aa) | ||||
PAU5 | Seripauperin-5; Member of the seripauperin multigene family; encoded mainly in subtelomeric regions; induced during alcoholic fermentation; induced by low temperature and also by anaerobic conditions; negatively regulated by oxygen and repressed by heme. (122 aa) | ||||
PAU11 | Putative protein of unknown function; member of the seripauperin multigene family encoded mainly in subtelomeric regions; mRNA expression appears to be regulated by SUT1 and UPC2. (120 aa) | ||||
PAU12 | Seripauperin-12; Protein of unknown function; member of the seripauperin multigene family encoded mainly in subtelomeric regions; SWAT-GFP fusion protein localizes to both the endoplasmic reticulum and vacuole. (120 aa) | ||||
PAU13 | Seripauperin-13; Protein of unknown function; member of the seripauperin multigene family encoded mainly in subtelomeric regions; expression is induced after ethanol shock; SWAT-GFP and mCherry fusion proteins localize to the endoplasmic reticulum and vacuole respectively; Belongs to the SRP1/TIP1 family. Seripauperin subfamily. (120 aa) | ||||
ANS1 | Probable GPI-anchored protein ANS1; Putative GPI protein; SWAT-GFP and mCherry fusion proteins localize to the vacuole; transcription dependent upon Azf1p. (159 aa) | ||||
TIR3 | Cell wall mannoprotein; member of Srp1p/Tip1p family of serine-alanine-rich proteins; expressed under anaerobic conditions and required for anaerobic growth; TIR3 has a paralog, TIR2, that arose from the whole genome duplication. (269 aa) | ||||
PAU14 | Seripauperin-14; Protein of unknown function; member of the seripauperin multigene family encoded mainly in subtelomeric regions; identical to Pau1p; Belongs to the SRP1/TIP1 family. Seripauperin subfamily. (120 aa) | ||||
PAU15 | Seripauperin-15; Protein of unknown function; member of the seripauperin multigene family encoded mainly in subtelomeric regions; SWAT-GFP and mCherry fusion proteins localize to the vacuole; Belongs to the SRP1/TIP1 family. Seripauperin subfamily. (124 aa) | ||||
CIS3 | Cell wall mannoprotein CIS3; Mannose-containing glycoprotein constituent of the cell wall; member of the PIR (proteins with internal repeats) family. (227 aa) | ||||
HSP150 | Cell wall mannoprotein HSP150; O-mannosylated heat shock protein; secreted and covalently attached to the cell wall via beta-1,3-glucan and disulfide bridges; required for cell wall stability; induced by heat shock, oxidative stress, and nitrogen limitation; HSP150 has a paralog, PIR3, that arose from the whole genome duplication. (413 aa) | ||||
PIR5 | Cell wall protein PIR5; Putative protein of unknown function; member of the PIR (Proteins with Internal Repeats) family of cell wall proteins; SWAT-GFP fusion protein localizes to the endoplasmic reticulum and vacuole, and mCherry fusion localizes to the vacuole; non-essential gene that is required for sporulation; mRNA is weakly cell cycle regulated, peaking in mitosis; YJL160C has a paralog, PIR1, that arose from the whole genome duplication. (287 aa) | ||||
PAU1 | Member of the seripauperin multigene family; encoded mainly in subtelomeric regions; SWAT-GFP and mCherry fusion proteins localize to the vacuole; active during alcoholic fermentation; regulated by anaerobiosis, negatively regulated by oxygen; repressed by heme; identical to Pau14p. (120 aa) | ||||
DAN1 | Cell wall mannoprotein; has similarity to Tir1p, Tir2p, Tir3p, and Tir4p; expressed under anaerobic conditions, completely repressed during aerobic growth. (298 aa) | ||||
DAN4 | Cell wall mannoprotein; has similarity to Tir1p, Tir2p, Tir3p, and Tir4p; expressed under anaerobic conditions, completely repressed during aerobic growth; Belongs to the SRP1/TIP1 family. (1161 aa) | ||||
CWP1 | Cell wall mannoprotein that localizes to birth scars of daughter cells; linked to a beta-1,3- and beta-1,6-glucan heteropolymer through a phosphodiester bond; required for propionic acid resistance; Belongs to the SRP1/TIP1 family. (239 aa) | ||||
CWP2 | Covalently linked cell wall mannoprotein; major constituent of the cell wall; plays a role in stabilizing the cell wall; involved in low pH resistance; precursor is GPI-anchored. (92 aa) | ||||
PIR3 | O-glycosylated covalently-bound cell wall protein; required for cell wall stability; expression is cell cycle regulated, peaking in M/G1 and also subject to regulation by the cell integrity pathway; coding sequence contains length polymorphisms in different strains; PIR3 has a paralog, HSP150, that arose from the whole genome duplication. (325 aa) | ||||
PIR1 | O-glycosylated protein required for cell wall stability; attached to the cell wall via beta-1,3-glucan; mediates mitochondrial translocation of Apn1p; expression regulated by the cell integrity pathway and by Swi5p during the cell cycle; PIR1 has a paralog, YJL160C, that arose from the whole genome duplication. (341 aa) | ||||
PAU16 | Seripauperin-16; Protein of unknown function; member of the seripauperin multigene family encoded mainly in subtelomeric regions; SWAT-GFP and mCherry fusion proteins localize to the vacuole; Belongs to the SRP1/TIP1 family. Seripauperin subfamily. (123 aa) | ||||
PAU17 | Seripauperin-17; Protein of unknown function; member of the seripauperin multigene family encoded mainly in subtelomeric regions; SWAT-GFP and mCherry fusion proteins localize to the vacuole; YLL025W is not an essential gene; Belongs to the SRP1/TIP1 family. Seripauperin subfamily. (124 aa) | ||||
PAU18 | Seripauperin-18; Protein of unknown function; member of the seripauperin multigene family encoded mainly in subtelomeric regions; identical to Pau6p; Belongs to the SRP1/TIP1 family. Seripauperin subfamily. (120 aa) | ||||
PAU23 | Seripauperin-23; Cell wall mannoprotein; has similarity to Tir1p, Tir2p, Tir3p, and Tir4p; member of the seripauperin multigene family encoded mainly in subtelomeric regions; expressed under anaerobic conditions, completely repressed during aerobic growth; Belongs to the SRP1/TIP1 family. Seripauperin subfamily. (124 aa) | ||||
CCW12 | Cell wall mannoprotein; plays a role in maintenance of newly synthesized areas of cell wall; localizes to periphery of small buds, septum region of larger buds, and shmoo tip; CCW12 has a paralog, YDR134C, that arose from the whole genome duplication. (133 aa) | ||||
CCW14 | Covalently linked cell wall glycoprotein; present in the inner layer of the cell wall; Belongs to the CCW14 family. (238 aa) | ||||
PAU4 | Seripauperin-4; Member of the seripauperin multigene family; encoded mainly in subtelomeric regions; SWAT-GFP fusion protein localizes to the endoplasmic reticulum and vacuole, while mCherry fusion localizes to just the vacuole; active during alcoholic fermentation; regulated by anaerobiosis; negatively regulated by oxygen; repressed by heme. (120 aa) |