node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BUD25 | BUD5 | YER014C-A | YCR038C | Protein involved in bud-site selection; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern. | Bud site selection protein 5; GTP/GDP exchange factor for Rsr1p (Bud1p); required for both axial and bipolar budding patterns; mutants exhibit random budding in all cell types. | 0.759 |
BUD25 | DSE1 | YER014C-A | YER124C | Protein involved in bud-site selection; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern. | Protein DSE1; Daughter cell-specific protein; may regulate cross-talk between the mating and filamentation pathways; deletion affects cell separation after division and sensitivity to alpha-factor and drugs affecting the cell wall; relocalizes from bud neck to cytoplasm upon DNA replication stress; Belongs to the WD repeat DSE1 family. | 0.698 |
BUD25 | DSE2 | YER014C-A | YHR143W | Protein involved in bud-site selection; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern. | Protein DSE2; Daughter cell-specific secreted protein with similarity to glucanases; degrades cell wall from the daughter side causing daughter to separate from mother; expression is repressed by cAMP. | 0.698 |
BUD25 | EGT2 | YER014C-A | YNL327W | Protein involved in bud-site selection; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern. | Protein EGT2; Glycosylphosphatidylinositol (GPI)-anchored cell wall endoglucanase; required for proper cell separation after cytokinesis; expression is activated by Swi5p and tightly regulated in a cell cycle-dependent manner. | 0.697 |
BUD25 | RAX1 | YER014C-A | YOR301W | Protein involved in bud-site selection; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern. | Protein involved in bud site selection during bipolar budding; localization requires Rax2p; has similarity to members of the insulin-related peptide superfamily. | 0.750 |
BUD25 | RAX2 | YER014C-A | YLR084C | Protein involved in bud-site selection; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern. | Bud site selection protein RAX2; N-glycosylated protein; involved in the maintenance of bud site selection during bipolar budding; localization requires Rax1p; RAX2 mRNA stability is regulated by Mpt5p. | 0.691 |
BUD5 | BUD25 | YCR038C | YER014C-A | Bud site selection protein 5; GTP/GDP exchange factor for Rsr1p (Bud1p); required for both axial and bipolar budding patterns; mutants exhibit random budding in all cell types. | Protein involved in bud-site selection; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern. | 0.759 |
BUD5 | DSE1 | YCR038C | YER124C | Bud site selection protein 5; GTP/GDP exchange factor for Rsr1p (Bud1p); required for both axial and bipolar budding patterns; mutants exhibit random budding in all cell types. | Protein DSE1; Daughter cell-specific protein; may regulate cross-talk between the mating and filamentation pathways; deletion affects cell separation after division and sensitivity to alpha-factor and drugs affecting the cell wall; relocalizes from bud neck to cytoplasm upon DNA replication stress; Belongs to the WD repeat DSE1 family. | 0.510 |
BUD5 | DSE2 | YCR038C | YHR143W | Bud site selection protein 5; GTP/GDP exchange factor for Rsr1p (Bud1p); required for both axial and bipolar budding patterns; mutants exhibit random budding in all cell types. | Protein DSE2; Daughter cell-specific secreted protein with similarity to glucanases; degrades cell wall from the daughter side causing daughter to separate from mother; expression is repressed by cAMP. | 0.485 |
BUD5 | EGT2 | YCR038C | YNL327W | Bud site selection protein 5; GTP/GDP exchange factor for Rsr1p (Bud1p); required for both axial and bipolar budding patterns; mutants exhibit random budding in all cell types. | Protein EGT2; Glycosylphosphatidylinositol (GPI)-anchored cell wall endoglucanase; required for proper cell separation after cytokinesis; expression is activated by Swi5p and tightly regulated in a cell cycle-dependent manner. | 0.463 |
BUD5 | RAX1 | YCR038C | YOR301W | Bud site selection protein 5; GTP/GDP exchange factor for Rsr1p (Bud1p); required for both axial and bipolar budding patterns; mutants exhibit random budding in all cell types. | Protein involved in bud site selection during bipolar budding; localization requires Rax2p; has similarity to members of the insulin-related peptide superfamily. | 0.836 |
BUD5 | RAX2 | YCR038C | YLR084C | Bud site selection protein 5; GTP/GDP exchange factor for Rsr1p (Bud1p); required for both axial and bipolar budding patterns; mutants exhibit random budding in all cell types. | Bud site selection protein RAX2; N-glycosylated protein; involved in the maintenance of bud site selection during bipolar budding; localization requires Rax1p; RAX2 mRNA stability is regulated by Mpt5p. | 0.807 |
DSE1 | BUD25 | YER124C | YER014C-A | Protein DSE1; Daughter cell-specific protein; may regulate cross-talk between the mating and filamentation pathways; deletion affects cell separation after division and sensitivity to alpha-factor and drugs affecting the cell wall; relocalizes from bud neck to cytoplasm upon DNA replication stress; Belongs to the WD repeat DSE1 family. | Protein involved in bud-site selection; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern. | 0.698 |
DSE1 | BUD5 | YER124C | YCR038C | Protein DSE1; Daughter cell-specific protein; may regulate cross-talk between the mating and filamentation pathways; deletion affects cell separation after division and sensitivity to alpha-factor and drugs affecting the cell wall; relocalizes from bud neck to cytoplasm upon DNA replication stress; Belongs to the WD repeat DSE1 family. | Bud site selection protein 5; GTP/GDP exchange factor for Rsr1p (Bud1p); required for both axial and bipolar budding patterns; mutants exhibit random budding in all cell types. | 0.510 |
DSE1 | DSE2 | YER124C | YHR143W | Protein DSE1; Daughter cell-specific protein; may regulate cross-talk between the mating and filamentation pathways; deletion affects cell separation after division and sensitivity to alpha-factor and drugs affecting the cell wall; relocalizes from bud neck to cytoplasm upon DNA replication stress; Belongs to the WD repeat DSE1 family. | Protein DSE2; Daughter cell-specific secreted protein with similarity to glucanases; degrades cell wall from the daughter side causing daughter to separate from mother; expression is repressed by cAMP. | 0.980 |
DSE1 | EGT2 | YER124C | YNL327W | Protein DSE1; Daughter cell-specific protein; may regulate cross-talk between the mating and filamentation pathways; deletion affects cell separation after division and sensitivity to alpha-factor and drugs affecting the cell wall; relocalizes from bud neck to cytoplasm upon DNA replication stress; Belongs to the WD repeat DSE1 family. | Protein EGT2; Glycosylphosphatidylinositol (GPI)-anchored cell wall endoglucanase; required for proper cell separation after cytokinesis; expression is activated by Swi5p and tightly regulated in a cell cycle-dependent manner. | 0.925 |
DSE1 | RAX1 | YER124C | YOR301W | Protein DSE1; Daughter cell-specific protein; may regulate cross-talk between the mating and filamentation pathways; deletion affects cell separation after division and sensitivity to alpha-factor and drugs affecting the cell wall; relocalizes from bud neck to cytoplasm upon DNA replication stress; Belongs to the WD repeat DSE1 family. | Protein involved in bud site selection during bipolar budding; localization requires Rax2p; has similarity to members of the insulin-related peptide superfamily. | 0.538 |
DSE1 | RAX2 | YER124C | YLR084C | Protein DSE1; Daughter cell-specific protein; may regulate cross-talk between the mating and filamentation pathways; deletion affects cell separation after division and sensitivity to alpha-factor and drugs affecting the cell wall; relocalizes from bud neck to cytoplasm upon DNA replication stress; Belongs to the WD repeat DSE1 family. | Bud site selection protein RAX2; N-glycosylated protein; involved in the maintenance of bud site selection during bipolar budding; localization requires Rax1p; RAX2 mRNA stability is regulated by Mpt5p. | 0.639 |
DSE2 | BUD25 | YHR143W | YER014C-A | Protein DSE2; Daughter cell-specific secreted protein with similarity to glucanases; degrades cell wall from the daughter side causing daughter to separate from mother; expression is repressed by cAMP. | Protein involved in bud-site selection; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern. | 0.698 |
DSE2 | BUD5 | YHR143W | YCR038C | Protein DSE2; Daughter cell-specific secreted protein with similarity to glucanases; degrades cell wall from the daughter side causing daughter to separate from mother; expression is repressed by cAMP. | Bud site selection protein 5; GTP/GDP exchange factor for Rsr1p (Bud1p); required for both axial and bipolar budding patterns; mutants exhibit random budding in all cell types. | 0.485 |