Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DST1 | RPB11 | YGL043W | YOL005C | General transcription elongation factor TFIIS; enables RNA polymerase II to read through blocks to elongation by stimulating cleavage of nascent transcripts stalled at transcription arrest sites; maintains RNAPII elongation activity on ribosomal protein genes during conditions of transcriptional stress; Belongs to the TFS-II family. | RNA polymerase II subunit B12.5; part of central core; similar to Rpc19p and bacterial alpha subunit. | 0.999 |
| DST1 | RPB2 | YGL043W | YOR151C | General transcription elongation factor TFIIS; enables RNA polymerase II to read through blocks to elongation by stimulating cleavage of nascent transcripts stalled at transcription arrest sites; maintains RNAPII elongation activity on ribosomal protein genes during conditions of transcriptional stress; Belongs to the TFS-II family. | RNA polymerase II second largest subunit B150; part of central core; similar to bacterial beta subunit. | 0.999 |
| DST1 | RPB3 | YGL043W | YIL021W | General transcription elongation factor TFIIS; enables RNA polymerase II to read through blocks to elongation by stimulating cleavage of nascent transcripts stalled at transcription arrest sites; maintains RNAPII elongation activity on ribosomal protein genes during conditions of transcriptional stress; Belongs to the TFS-II family. | RNA polymerase II third largest subunit B44; part of central core; similar to prokaryotic alpha subunit. | 0.999 |
| DST1 | RPB4 | YGL043W | YJL140W | General transcription elongation factor TFIIS; enables RNA polymerase II to read through blocks to elongation by stimulating cleavage of nascent transcripts stalled at transcription arrest sites; maintains RNAPII elongation activity on ribosomal protein genes during conditions of transcriptional stress; Belongs to the TFS-II family. | RNA polymerase II subunit B32; forms dissociable heterodimer with Rpb7p; Rpb4/7 dissociates from RNAPII as Ser2 CTD phosphorylation increases; Rpb4/7 regulates cellular lifespan via mRNA decay process; involved in recruitment of 3'-end processing factors to transcribing RNAPII complex, export of mRNA to cytoplasm under stress conditions; also involved in translation initiation. | 0.999 |
| DST1 | RPB5 | YGL043W | YBR154C | General transcription elongation factor TFIIS; enables RNA polymerase II to read through blocks to elongation by stimulating cleavage of nascent transcripts stalled at transcription arrest sites; maintains RNAPII elongation activity on ribosomal protein genes during conditions of transcriptional stress; Belongs to the TFS-II family. | RNA polymerase subunit ABC27; common to RNA polymerases I, II, and III; contacts DNA and affects transactivation; Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family. | 0.999 |
| DST1 | RPB9 | YGL043W | YGL070C | General transcription elongation factor TFIIS; enables RNA polymerase II to read through blocks to elongation by stimulating cleavage of nascent transcripts stalled at transcription arrest sites; maintains RNAPII elongation activity on ribosomal protein genes during conditions of transcriptional stress; Belongs to the TFS-II family. | RNA polymerase II subunit B12.6; contacts DNA; mutations affect transcription start site selection and fidelity of transcription. | 0.999 |
| DST1 | RPO21 | YGL043W | YDL140C | General transcription elongation factor TFIIS; enables RNA polymerase II to read through blocks to elongation by stimulating cleavage of nascent transcripts stalled at transcription arrest sites; maintains RNAPII elongation activity on ribosomal protein genes during conditions of transcriptional stress; Belongs to the TFS-II family. | RNA polymerase II largest subunit B220; part of central core; phosphorylation of C-terminal heptapeptide repeat domain regulates association with transcription and splicing factors; similar to bacterial beta-prime. | 0.999 |
| DST1 | SPT15 | YGL043W | YER148W | General transcription elongation factor TFIIS; enables RNA polymerase II to read through blocks to elongation by stimulating cleavage of nascent transcripts stalled at transcription arrest sites; maintains RNAPII elongation activity on ribosomal protein genes during conditions of transcriptional stress; Belongs to the TFS-II family. | TATA-binding protein (TBP); general transcription factor that interacts with other factors to form the preinitiation complex at promoters; essential for viability, highly conserved; yeast gene can complement mutations in human homolog TBP. | 0.995 |
| DST1 | SUA7 | YGL043W | YPR086W | General transcription elongation factor TFIIS; enables RNA polymerase II to read through blocks to elongation by stimulating cleavage of nascent transcripts stalled at transcription arrest sites; maintains RNAPII elongation activity on ribosomal protein genes during conditions of transcriptional stress; Belongs to the TFS-II family. | Transcription factor TFIIB; a general transcription factor required for transcription initiation and start site selection by RNA polymerase II. | 0.998 |
| POL4 | RPB2 | YCR014C | YOR151C | DNA polymerase IV; undergoes pair-wise interactions with Dnl4p-Lif1p and Rad27p to mediate repair of DNA double-strand breaks by non-homologous end joining (NHEJ); homologous to mammalian DNA polymerase beta. | RNA polymerase II second largest subunit B150; part of central core; similar to bacterial beta subunit. | 0.498 |
| POL4 | RPB5 | YCR014C | YBR154C | DNA polymerase IV; undergoes pair-wise interactions with Dnl4p-Lif1p and Rad27p to mediate repair of DNA double-strand breaks by non-homologous end joining (NHEJ); homologous to mammalian DNA polymerase beta. | RNA polymerase subunit ABC27; common to RNA polymerases I, II, and III; contacts DNA and affects transactivation; Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family. | 0.418 |
| POL4 | RPO21 | YCR014C | YDL140C | DNA polymerase IV; undergoes pair-wise interactions with Dnl4p-Lif1p and Rad27p to mediate repair of DNA double-strand breaks by non-homologous end joining (NHEJ); homologous to mammalian DNA polymerase beta. | RNA polymerase II largest subunit B220; part of central core; phosphorylation of C-terminal heptapeptide repeat domain regulates association with transcription and splicing factors; similar to bacterial beta-prime. | 0.494 |
| RPB11 | DST1 | YOL005C | YGL043W | RNA polymerase II subunit B12.5; part of central core; similar to Rpc19p and bacterial alpha subunit. | General transcription elongation factor TFIIS; enables RNA polymerase II to read through blocks to elongation by stimulating cleavage of nascent transcripts stalled at transcription arrest sites; maintains RNAPII elongation activity on ribosomal protein genes during conditions of transcriptional stress; Belongs to the TFS-II family. | 0.999 |
| RPB11 | RPB2 | YOL005C | YOR151C | RNA polymerase II subunit B12.5; part of central core; similar to Rpc19p and bacterial alpha subunit. | RNA polymerase II second largest subunit B150; part of central core; similar to bacterial beta subunit. | 0.999 |
| RPB11 | RPB3 | YOL005C | YIL021W | RNA polymerase II subunit B12.5; part of central core; similar to Rpc19p and bacterial alpha subunit. | RNA polymerase II third largest subunit B44; part of central core; similar to prokaryotic alpha subunit. | 0.999 |
| RPB11 | RPB4 | YOL005C | YJL140W | RNA polymerase II subunit B12.5; part of central core; similar to Rpc19p and bacterial alpha subunit. | RNA polymerase II subunit B32; forms dissociable heterodimer with Rpb7p; Rpb4/7 dissociates from RNAPII as Ser2 CTD phosphorylation increases; Rpb4/7 regulates cellular lifespan via mRNA decay process; involved in recruitment of 3'-end processing factors to transcribing RNAPII complex, export of mRNA to cytoplasm under stress conditions; also involved in translation initiation. | 0.999 |
| RPB11 | RPB5 | YOL005C | YBR154C | RNA polymerase II subunit B12.5; part of central core; similar to Rpc19p and bacterial alpha subunit. | RNA polymerase subunit ABC27; common to RNA polymerases I, II, and III; contacts DNA and affects transactivation; Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family. | 0.999 |
| RPB11 | RPB9 | YOL005C | YGL070C | RNA polymerase II subunit B12.5; part of central core; similar to Rpc19p and bacterial alpha subunit. | RNA polymerase II subunit B12.6; contacts DNA; mutations affect transcription start site selection and fidelity of transcription. | 0.999 |
| RPB11 | RPO21 | YOL005C | YDL140C | RNA polymerase II subunit B12.5; part of central core; similar to Rpc19p and bacterial alpha subunit. | RNA polymerase II largest subunit B220; part of central core; phosphorylation of C-terminal heptapeptide repeat domain regulates association with transcription and splicing factors; similar to bacterial beta-prime. | 0.999 |
| RPB11 | SPT15 | YOL005C | YER148W | RNA polymerase II subunit B12.5; part of central core; similar to Rpc19p and bacterial alpha subunit. | TATA-binding protein (TBP); general transcription factor that interacts with other factors to form the preinitiation complex at promoters; essential for viability, highly conserved; yeast gene can complement mutations in human homolog TBP. | 0.978 |
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