(9 nodes) Streptomycin biosynthesis network (Methanobrevibacter curvatus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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gene neighborhood

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Your Input:
	rmlA_1	Glucose-1-phosphate thymidylyltransferase. (430 aa)
	rfbC	dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (182 aa)
	ino1	Inositol-3-phosphate synthase. (368 aa)
	strL	dTDP-4-dehydrorhamnose reductase. (287 aa)
	rmlA_2	Glucose-1-phosphate thymidylyltransferase. (291 aa)
	algC	Phosphomannomutase/phosphoglucomutase; Belongs to the phosphohexose mutase family. (453 aa)
	rmlC	dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (184 aa)
	rfbB	dTDP-glucose 4,6-dehydratase. (334 aa)
	glmM_2	Phosphoglucosamine mutase; Belongs to the phosphohexose mutase family. (454 aa)

Your Current Organism:

Methanobrevibacter curvatus

NCBI taxonomy Id: 49547
Other names: DSM 11111, M. curvatus, strain RFM-2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
algC	ino1	MBCUR_14510	MBCUR_13800	Phosphomannomutase/phosphoglucomutase; Belongs to the phosphohexose mutase family.	Inositol-3-phosphate synthase.	0.666
algC	rmlA_1	MBCUR_14510	MBCUR_03940	Phosphomannomutase/phosphoglucomutase; Belongs to the phosphohexose mutase family.	Glucose-1-phosphate thymidylyltransferase.	0.983
algC	rmlA_2	MBCUR_14510	MBCUR_14200	Phosphomannomutase/phosphoglucomutase; Belongs to the phosphohexose mutase family.	Glucose-1-phosphate thymidylyltransferase.	0.753
glmM_2	ino1	MBCUR_04770	MBCUR_13800	Phosphoglucosamine mutase; Belongs to the phosphohexose mutase family.	Inositol-3-phosphate synthase.	0.666
glmM_2	rmlA_1	MBCUR_04770	MBCUR_03940	Phosphoglucosamine mutase; Belongs to the phosphohexose mutase family.	Glucose-1-phosphate thymidylyltransferase.	0.983
glmM_2	rmlA_2	MBCUR_04770	MBCUR_14200	Phosphoglucosamine mutase; Belongs to the phosphohexose mutase family.	Glucose-1-phosphate thymidylyltransferase.	0.753
ino1	algC	MBCUR_13800	MBCUR_14510	Inositol-3-phosphate synthase.	Phosphomannomutase/phosphoglucomutase; Belongs to the phosphohexose mutase family.	0.666
ino1	glmM_2	MBCUR_13800	MBCUR_04770	Inositol-3-phosphate synthase.	Phosphoglucosamine mutase; Belongs to the phosphohexose mutase family.	0.666
rfbB	rfbC	MBCUR_15690	MBCUR_06650	dTDP-glucose 4,6-dehydratase.	dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.	0.979
rfbB	rmlA_1	MBCUR_15690	MBCUR_03940	dTDP-glucose 4,6-dehydratase.	Glucose-1-phosphate thymidylyltransferase.	0.993
rfbB	rmlA_2	MBCUR_15690	MBCUR_14200	dTDP-glucose 4,6-dehydratase.	Glucose-1-phosphate thymidylyltransferase.	0.995
rfbB	rmlC	MBCUR_15690	MBCUR_15680	dTDP-glucose 4,6-dehydratase.	dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.	0.989
rfbB	strL	MBCUR_15690	MBCUR_14190	dTDP-glucose 4,6-dehydratase.	dTDP-4-dehydrorhamnose reductase.	0.999
rfbC	rfbB	MBCUR_06650	MBCUR_15690	dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.	dTDP-glucose 4,6-dehydratase.	0.979
rfbC	rmlA_1	MBCUR_06650	MBCUR_03940	dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.	Glucose-1-phosphate thymidylyltransferase.	0.589
rfbC	rmlA_2	MBCUR_06650	MBCUR_14200	dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.	Glucose-1-phosphate thymidylyltransferase.	0.745
rfbC	strL	MBCUR_06650	MBCUR_14190	dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.	dTDP-4-dehydrorhamnose reductase.	0.991
rmlA_1	algC	MBCUR_03940	MBCUR_14510	Glucose-1-phosphate thymidylyltransferase.	Phosphomannomutase/phosphoglucomutase; Belongs to the phosphohexose mutase family.	0.983
rmlA_1	glmM_2	MBCUR_03940	MBCUR_04770	Glucose-1-phosphate thymidylyltransferase.	Phosphoglucosamine mutase; Belongs to the phosphohexose mutase family.	0.983
rmlA_1	rfbB	MBCUR_03940	MBCUR_15690	Glucose-1-phosphate thymidylyltransferase.	dTDP-glucose 4,6-dehydratase.	0.993