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| | FEN1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (378 aa) |
| | B9J08_000255 | Transcriptional adapter 2; Functions as component of the transcription regulatory histone acetylation (HAT) complexes SAGA, SALSA and ADA. SAGA is involved in RNA polymerase II-dependent transcriptional regulation. (441 aa) |
| | B9J08_000225 | Uncharacterized protein. (262 aa) |
| | B9J08_000395 | Uncharacterized protein. (1101 aa) |
| | B9J08_001023 | Uncharacterized protein. (133 aa) |
| | B9J08_000282 | PHD-type domain-containing protein. (392 aa) |
| | B9J08_000281 | WD_REPEATS_REGION domain-containing protein. (452 aa) |
| | B9J08_001012 | SWIRM domain-containing protein. (343 aa) |
| | B9J08_000215 | DNA-directed RNA polymerase I, II, and III subunit RPABC5. (72 aa) |
| | B9J08_000860 | Uncharacterized protein. (241 aa) |
| | B9J08_000137 | Uncharacterized protein. (391 aa) |
| | B9J08_001045 | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1235 aa) |
| | B9J08_000923 | SANT domain-containing protein. (558 aa) |
| | B9J08_000600 | Uncharacterized protein. (444 aa) |
| | B9J08_000883 | Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (406 aa) |
| | B9J08_000815 | WD_REPEATS_REGION domain-containing protein. (641 aa) |
| | B9J08_000752 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (840 aa) |
| | B9J08_000704 | Uncharacterized protein. (1470 aa) |
| | B9J08_000706 | HSA domain-containing protein. (1095 aa) |
| | B9J08_000679 | Uncharacterized protein. (149 aa) |
| | B9J08_000629 | SAS4 domain-containing protein. (261 aa) |
| | B9J08_000550 | Uncharacterized protein. (396 aa) |
| | B9J08_000667 | Uncharacterized protein. (156 aa) |
| | B9J08_000531 | Uncharacterized protein. (116 aa) |
| | B9J08_001047 | DNA-directed RNA polymerase II subunit rpb7. (173 aa) |
| | B9J08_000533 | Uncharacterized protein. (327 aa) |
| | B9J08_000869 | Uncharacterized protein. (612 aa) |
| | B9J08_000637 | Uncharacterized protein. (628 aa) |
| | B9J08_000612 | RNase_PH domain-containing protein. (353 aa) |
| | B9J08_000541 | Uncharacterized protein. (457 aa) |
| | B9J08_000394 | Uncharacterized protein. (175 aa) |
| | B9J08_000294 | Uncharacterized protein. (143 aa) |
| | B9J08_001378 | BSD domain-containing protein. (640 aa) |
| | B9J08_000087 | DNA helicase; Belongs to the MCM family. (729 aa) |
| | B9J08_001181 | Uncharacterized protein. (419 aa) |
| | B9J08_001444 | Transcription elongation factor 1 homolog; Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions. Belongs to the ELOF1 family. (119 aa) |
| | B9J08_001434 | Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. (234 aa) |
| | B9J08_001149 | Uncharacterized protein. (1547 aa) |
| | B9J08_001425 | Uncharacterized protein. (257 aa) |
| | B9J08_001400 | Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (571 aa) |
| | B9J08_001354 | TATA-box-binding protein 1. (238 aa) |
| | B9J08_001346 | Uncharacterized protein. (369 aa) |
| | B9J08_001320 | Uncharacterized protein. (426 aa) |
| | B9J08_001256 | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1762 aa) |
| | B9J08_001246 | DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (235 aa) |
| | B9J08_001105 | DNA helicase; Belongs to the MCM family. (930 aa) |
| | B9J08_001101 | Uncharacterized protein. (943 aa) |
| | B9J08_001343 | DNA repair helicase RAD3. (793 aa) |
| | B9J08_001655 | Uncharacterized protein. (644 aa) |
| | B9J08_001140 | TAF4 domain-containing protein. (554 aa) |
| | B9J08_001349 | SCA7 domain-containing protein. (493 aa) |
| | B9J08_001872 | Uncharacterized protein. (330 aa) |
| | B9J08_001735 | Uncharacterized protein. (372 aa) |
| | B9J08_001692 | AAA_16 domain-containing protein. (437 aa) |
| | B9J08_001681 | ORC_WH_C domain-containing protein. (729 aa) |
| | B9J08_001626 | Uncharacterized protein. (1564 aa) |
| | B9J08_001599 | CENP-T_C domain-containing protein. (623 aa) |
| | B9J08_002224 | FACT complex subunit SPT16. (1031 aa) |
| | B9J08_002562 | Uncharacterized protein. (745 aa) |
| | B9J08_002196 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (353 aa) |
| | B9J08_002048 | CDK-activating kinase assembly factor MAT1. (276 aa) |
| | B9J08_002041 | Midasin; Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits; Belongs to the midasin family. (4946 aa) |
| | B9J08_002348 | Nucleolar complex-associated protein 3; Required for synthesis of 60S ribosomal subunits and the transport of pre-ribosomes from the nucleoplasm to the cytoplasm. Belongs to the CBF/MAK21 family. (671 aa) |
| | B9J08_001979 | DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (148 aa) |
| | B9J08_003936 | SANT domain-containing protein. (1230 aa) |
| | MCM7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (786 aa) |
| | B9J08_002354 | DRIM domain-containing protein. (2463 aa) |
| | B9J08_002383 | Uncharacterized protein. (283 aa) |
| | B9J08_002321 | Peptidase_M24 domain-containing protein. (566 aa) |
| | B9J08_002318 | Uncharacterized protein. (502 aa) |
| | B9J08_003645 | FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] (539 aa) |
| | B9J08_002281 | Uncharacterized protein. (1138 aa) |
| | B9J08_004025 | Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (281 aa) |
| | B9J08_003426 | HDAC_interact domain-containing protein. (1576 aa) |
| | B9J08_003322 | PHD domain-containing protein. (1094 aa) |
| | B9J08_003774 | RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. (457 aa) |
| | B9J08_003741 | Uncharacterized protein. (181 aa) |
| | B9J08_003379 | Uncharacterized protein; Belongs to the SKP1 family. (101 aa) |
| | B9J08_003257 | CDC73_C domain-containing protein. (362 aa) |
| | B9J08_002679 | Enhancer of polycomb-like protein. (936 aa) |
| | B9J08_003150 | WD_REPEATS_REGION domain-containing protein. (354 aa) |
| | B9J08_002988 | Uncharacterized protein; Belongs to the actin family. (475 aa) |
| | B9J08_001773 | TAFII55_N domain-containing protein. (560 aa) |
| | B9J08_002787 | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (112 aa) |
| | B9J08_004039 | Uncharacterized protein. (489 aa) |
| | SGF11 | SAGA-associated factor 11; Functions as component of the transcription regulatory histone acetylation (HAT) complex SAGA. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. SAGA acetylates nucleosomal histone H3 to some extent (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac). SAGA interacts with DNA [...] (105 aa) |
| | B9J08_003937 | Cell division control protein; Belongs to the CDC6/cdc18 family. (484 aa) |
| | B9J08_002075 | Uncharacterized protein. (345 aa) |
| | B9J08_002004 | Uncharacterized protein. (730 aa) |
| | B9J08_004073 | Uncharacterized protein. (154 aa) |
| | B9J08_003949 | Uncharacterized protein. (757 aa) |
| | B9J08_003940 | DNA-directed RNA polymerase I, II, and III subunit RPABC1. (213 aa) |
| | B9J08_003892 | AAA domain-containing protein. (644 aa) |
| | B9J08_003862 | General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family. (497 aa) |
| | B9J08_003842 | TAFII28 domain-containing protein. (257 aa) |
| | B9J08_003880 | DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (167 aa) |
| | B9J08_003861 | Transcription elongation factor SPT5; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene. (995 aa) |
| | B9J08_003814 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (513 aa) |
| | B9J08_003807 | Ubiquitin carboxyl-terminal hydrolase. (551 aa) |
| | B9J08_003412 | Uncharacterized protein. (597 aa) |
| | B9J08_003638 | Uncharacterized protein. (534 aa) |
| | B9J08_003607 | Uncharacterized protein. (347 aa) |
| | B9J08_003577 | TAF8_C domain-containing protein. (660 aa) |
| | B9J08_003545 | HTH TFE/IIEalpha-type domain-containing protein. (368 aa) |
| | B9J08_003588 | HIT-type domain-containing protein. (234 aa) |
| | B9J08_003505 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (846 aa) |
| | B9J08_003154 | Uncharacterized protein. (288 aa) |
| | B9J08_003176 | Uncharacterized protein. (448 aa) |
| | B9J08_003429 | Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (202 aa) |
| | B9J08_003447 | Chromatin modification-related protein. (368 aa) |
| | B9J08_003467 | DNA helicase; Belongs to the MCM family. (903 aa) |
| | B9J08_003425 | Uncharacterized protein. (120 aa) |
| | B9J08_003080 | Uncharacterized protein. (526 aa) |
| | B9J08_003013 | DNA repair helicase RAD25. (841 aa) |
| | B9J08_003287 | Plus3 domain-containing protein. (551 aa) |
| | B9J08_003201 | Uncharacterized protein. (1520 aa) |
| | B9J08_003131 | RPOL4c domain-containing protein. (190 aa) |
| | NOP7 | Pescadillo homolog; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (600 aa) |
| | B9J08_003022 | PHD domain-containing protein. (318 aa) |
| | B9J08_002634 | Protein kinase domain-containing protein. (705 aa) |
| | B9J08_002946 | Uncharacterized protein. (813 aa) |
| | B9J08_002894 | Uncharacterized protein; Belongs to the actin family. (404 aa) |
| | B9J08_002898 | Uncharacterized protein. (501 aa) |
| | B9J08_002897 | SLD3 domain-containing protein. (791 aa) |
| | B9J08_002859 | WD_REPEATS_REGION domain-containing protein. (435 aa) |
| | B9J08_002850 | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (452 aa) |
| | B9J08_002824 | CDT1_C domain-containing protein. (291 aa) |
| | B9J08_002750 | Bromo domain-containing protein. (1081 aa) |
| | B9J08_004340 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (331 aa) |
| | B9J08_004242 | HECT domain-containing protein. (1565 aa) |
| | B9J08_004247 | Transcription initiation factor TFIID subunit 10; Functions as a component of the DNA-binding general transcription factor complex TFIID and the transcription regulatory histone acetylation (HAT) complexes SAGA and SLIK. Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modificati [...] (212 aa) |
| | B9J08_004402 | Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene. (112 aa) |
| | B9J08_004311 | Uncharacterized protein. (195 aa) |
| | B9J08_004306 | B30.2/SPRY domain-containing protein. (476 aa) |
| | B9J08_004262 | Uncharacterized protein. (703 aa) |
| | SUS1 | Transcription and mRNA export factor SUS1; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex required for deubiquitination of [...] (96 aa) |
| | B9J08_004733 | Uncharacterized protein. (219 aa) |
| | B9J08_004845 | BTP domain-containing protein. (474 aa) |
| | B9J08_004856 | UV excision repair protein Rad23. (367 aa) |
| | B9J08_004516 | Uncharacterized protein. (981 aa) |
| | B9J08_005476 | DNA helicase; Belongs to the MCM family. (849 aa) |
| | B9J08_004747 | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (504 aa) |
| | B9J08_004694 | Uncharacterized protein. (153 aa) |
| | B9J08_004585 | Uncharacterized protein. (458 aa) |
| | B9J08_004578 | Uncharacterized protein. (678 aa) |
| | B9J08_004557 | ANK_REP_REGION domain-containing protein. (1211 aa) |
| | B9J08_005113 | RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (499 aa) |
| | B9J08_004520 | Uncharacterized protein. (778 aa) |
| | YTM1 | Ribosome biogenesis protein YTM1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (462 aa) |
| | B9J08_005356 | Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation. (1054 aa) |
| | B9J08_005271 | Uncharacterized protein. (364 aa) |
| | B9J08_005250 | CYCLIN domain-containing protein; Belongs to the cyclin family. (411 aa) |
| | B9J08_005240 | RXT2_N domain-containing protein. (334 aa) |
| | B9J08_005354 | Uncharacterized protein. (378 aa) |
| | B9J08_005137 | Uncharacterized protein. (496 aa) |
| | ERB1 | Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (821 aa) |
| | B9J08_005058 | Uncharacterized protein. (439 aa) |
| | B9J08_005038 | Uncharacterized protein. (308 aa) |
| | B9J08_005236 | Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (121 aa) |
| | B9J08_005136 | HORMA domain-containing protein. (204 aa) |
| | B9J08_005462 | Sld5 domain-containing protein. (218 aa) |
| | B9J08_005442 | WD_REPEATS_REGION domain-containing protein. (389 aa) |
| | B9J08_005398 | Uncharacterized protein. (377 aa) |
| | B9J08_005406 | Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (3805 aa) |
| | B9J08_005401 | Uncharacterized protein. (559 aa) |
| | B9J08_005361 | Uncharacterized protein. (268 aa) |
| | B9J08_005133 | Histone acetyltransferase GCN5. (522 aa) |
| | B9J08_005106 | Uncharacterized protein. (745 aa) |
| | B9J08_005074 | MRG domain-containing protein. (336 aa) |
| | B9J08_005055 | Uncharacterized protein. (230 aa) |
| | B9J08_004980 | Uncharacterized protein. (294 aa) |
| | B9J08_004932 | RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. (474 aa) |
| | B9J08_004684 | PHD-type domain-containing protein. (641 aa) |
