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| | B9J08_003645 | FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] (539 aa) |
| | B9J08_003272 | Uncharacterized protein. (831 aa) |
| | B9J08_003774 | RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. (457 aa) |
| | B9J08_003139 | WD_REPEATS_REGION domain-containing protein. (425 aa) |
| | B9J08_003554 | Uncharacterized protein. (133 aa) |
| | B9J08_003464 | Uncharacterized protein. (409 aa) |
| | B9J08_003421 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (749 aa) |
| | B9J08_003255 | Uncharacterized protein. (164 aa) |
| | B9J08_003102 | Checkpoint protein; Belongs to the HUS1 family. (320 aa) |
| | B9J08_002988 | Uncharacterized protein; Belongs to the actin family. (475 aa) |
| | B9J08_002122 | Uncharacterized protein. (234 aa) |
| | B9J08_004039 | Uncharacterized protein. (489 aa) |
| | SGF11 | SAGA-associated factor 11; Functions as component of the transcription regulatory histone acetylation (HAT) complex SAGA. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. SAGA acetylates nucleosomal histone H3 to some extent (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac). SAGA interacts with DNA [...] (105 aa) |
| | B9J08_001739 | Uncharacterized protein. (412 aa) |
| | B9J08_002075 | Uncharacterized protein. (345 aa) |
| | B9J08_002059 | Uncharacterized protein. (469 aa) |
| | B9J08_004000 | ANK_REP_REGION domain-containing protein. (1108 aa) |
| | B9J08_003996 | Histone H2A; Belongs to the histone H2A family. (132 aa) |
| | B9J08_003892 | AAA domain-containing protein. (644 aa) |
| | B9J08_003594 | USP domain-containing protein; Belongs to the peptidase C19 family. (675 aa) |
| | B9J08_003509 | Uncharacterized protein. (838 aa) |
| | B9J08_003814 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (513 aa) |
| | B9J08_003798 | Uncharacterized protein. (585 aa) |
| | B9J08_003720 | Uncharacterized protein. (1924 aa) |
| | B9J08_003661 | BCNT-C domain-containing protein. (309 aa) |
| | B9J08_003588 | HIT-type domain-containing protein. (234 aa) |
| | B9J08_003535 | Uncharacterized protein. (690 aa) |
| | B9J08_003534 | Uncharacterized protein. (398 aa) |
| | B9J08_003196 | tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37; Belongs to the IPP transferase family. (468 aa) |
| | B9J08_003505 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (846 aa) |
| | B9J08_003447 | Chromatin modification-related protein. (368 aa) |
| | B9J08_003114 | Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2356 aa) |
| | B9J08_003328 | Uncharacterized protein. (568 aa) |
| | B9J08_002797 | Uncharacterized protein. (476 aa) |
| | B9J08_002796 | Uncharacterized protein. (846 aa) |
| | B9J08_003022 | PHD domain-containing protein. (318 aa) |
| | B9J08_002946 | Uncharacterized protein. (813 aa) |
| | B9J08_002917 | Uncharacterized protein. (530 aa) |
| | B9J08_002894 | Uncharacterized protein; Belongs to the actin family. (404 aa) |
| | B9J08_002612 | Uncharacterized protein. (530 aa) |
| | B9J08_002859 | WD_REPEATS_REGION domain-containing protein. (435 aa) |
| | B9J08_002850 | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (452 aa) |
| | B9J08_002844 | Uncharacterized protein; Belongs to the actin family. (465 aa) |
| | B9J08_002832 | Uncharacterized protein. (1118 aa) |
| | B9J08_002793 | RING-type domain-containing protein. (1713 aa) |
| | B9J08_002750 | Bromo domain-containing protein. (1081 aa) |
| | B9J08_004401 | Bromo domain-containing protein. (1312 aa) |
| | B9J08_002595 | Uncharacterized protein. (740 aa) |
| | B9J08_004247 | Transcription initiation factor TFIID subunit 10; Functions as a component of the DNA-binding general transcription factor complex TFIID and the transcription regulatory histone acetylation (HAT) complexes SAGA and SLIK. Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modificati [...] (212 aa) |
| | B9J08_004508 | Ubiquitin-conjugating enzyme E2 7; Belongs to the ubiquitin-conjugating enzyme family. (167 aa) |
| | B9J08_004402 | Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene. (112 aa) |
| | B9J08_004334 | Homeobox domain-containing protein. (551 aa) |
| | B9J08_004306 | B30.2/SPRY domain-containing protein. (476 aa) |
| | B9J08_004234 | Uncharacterized protein. (355 aa) |
| | SUS1 | Transcription and mRNA export factor SUS1; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex required for deubiquitination of [...] (96 aa) |
| | B9J08_004733 | Uncharacterized protein. (219 aa) |
| | B9J08_004588 | Uncharacterized protein. (329 aa) |
| | B9J08_004643 | HUN domain-containing protein. (473 aa) |
| | B9J08_004693 | Uncharacterized protein. (455 aa) |
| | B9J08_004749 | TPR_REGION domain-containing protein. (894 aa) |
| | B9J08_004714 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (259 aa) |
| | B9J08_004647 | Ubiquitin-conjugating enzyme E2 2; Belongs to the ubiquitin-conjugating enzyme family. (163 aa) |
| | B9J08_004808 | Uncharacterized protein. (323 aa) |
| | B9J08_000781 | Uncharacterized protein; Belongs to the actin family. (461 aa) |
| | B9J08_000628 | Sister chromatid cohesion protein. (1470 aa) |
| | B9J08_000706 | HSA domain-containing protein. (1095 aa) |
| | B9J08_000688 | Uncharacterized protein. (496 aa) |
| | B9J08_000704 | Uncharacterized protein. (1470 aa) |
| | B9J08_000752 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (840 aa) |
| | B9J08_000815 | WD_REPEATS_REGION domain-containing protein. (641 aa) |
| | B9J08_000855 | H15 domain-containing protein. (242 aa) |
| | B9J08_000887 | Uncharacterized protein. (1060 aa) |
| | B9J08_000923 | SANT domain-containing protein. (558 aa) |
| | B9J08_000651 | Actin-related protein 8; Probably involved in transcription regulation via its interaction with the INO80 complex, a chromatin remodeling complex. Belongs to the actin family. (830 aa) |
| | B9J08_000044 | Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. (1119 aa) |
| | B9J08_000045 | ISWI chromatin-remodeling complex ATPase ISW2. (1071 aa) |
| | B9J08_000133 | SMC hinge domain-containing protein. (1169 aa) |
| | B9J08_000860 | Uncharacterized protein. (241 aa) |
| | B9J08_000240 | Rad60-SLD domain-containing protein. (387 aa) |
| | B9J08_001012 | SWIRM domain-containing protein. (343 aa) |
| | B9J08_000281 | WD_REPEATS_REGION domain-containing protein. (452 aa) |
| | B9J08_000282 | PHD-type domain-containing protein. (392 aa) |
| | B9J08_000364 | Uncharacterized protein. (1115 aa) |
| | B9J08_000421 | JmjC domain-containing protein. (534 aa) |
| | B9J08_002198 | Uncharacterized protein. (546 aa) |
| | B9J08_000255 | Transcriptional adapter 2; Functions as component of the transcription regulatory histone acetylation (HAT) complexes SAGA, SALSA and ADA. SAGA is involved in RNA polymerase II-dependent transcriptional regulation. (441 aa) |
| | B9J08_000488 | Uncharacterized protein. (824 aa) |
| | B9J08_000442 | Uncharacterized protein. (893 aa) |
| | B9J08_002221 | CHZ domain-containing protein. (171 aa) |
| | B9J08_002562 | Uncharacterized protein. (745 aa) |
| | B9J08_002196 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (353 aa) |
| | B9J08_002197 | Uncharacterized protein. (1171 aa) |
| | B9J08_002195 | Histone domain-containing protein. (240 aa) |
| | B9J08_002073 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa) |
| | B9J08_002085 | Histone chaperone; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. (240 aa) |
| | B9J08_002022 | Uncharacterized protein. (640 aa) |
| | B9J08_002024 | Uncharacterized protein. (746 aa) |
| | B9J08_001972 | Uncharacterized protein. (1303 aa) |
| | B9J08_001991 | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. (417 aa) |
| | B9J08_002518 | WD_REPEATS_REGION domain-containing protein. (421 aa) |
| | B9J08_002475 | Uncharacterized protein. (998 aa) |
| | B9J08_002458 | Histone acetyltransferase type B catalytic subunit; Catalytic component of the histone acetylase B (HAT-B) complex. Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Involved in DNA double-strand break repair; Belongs to the HAT1 family. (409 aa) |
| | MCM7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (786 aa) |
| | B9J08_002365 | Uncharacterized protein. (1271 aa) |
| | B9J08_002318 | Uncharacterized protein. (502 aa) |
| | B9J08_000550 | Uncharacterized protein. (396 aa) |
| | B9J08_000667 | Uncharacterized protein. (156 aa) |
| | B9J08_000533 | Uncharacterized protein. (327 aa) |
| | B9J08_001031 | Peptidylprolyl isomerase. (111 aa) |
| | B9J08_000637 | Uncharacterized protein. (628 aa) |
| | B9J08_001479 | Uncharacterized protein. (459 aa) |
| | B9J08_001469 | MRC1 domain-containing protein. (1071 aa) |
| | B9J08_000332 | Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (784 aa) |
| | B9J08_001468 | Uncharacterized protein. (550 aa) |
| | B9J08_000294 | Uncharacterized protein. (143 aa) |
| | B9J08_000087 | DNA helicase; Belongs to the MCM family. (729 aa) |
| | B9J08_001282 | Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family. (250 aa) |
| | B9J08_000031 | Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family. (407 aa) |
| | B9J08_001262 | Csm1 domain-containing protein. (261 aa) |
| | B9J08_001211 | Uncharacterized protein. (2004 aa) |
| | B9J08_001501 | Uncharacterized protein. (902 aa) |
| | B9J08_001444 | Transcription elongation factor 1 homolog; Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions. Belongs to the ELOF1 family. (119 aa) |
| | B9J08_001130 | Uncharacterized protein. (1299 aa) |
| | B9J08_001149 | Uncharacterized protein. (1547 aa) |
| | B9J08_001412 | Uncharacterized protein. (600 aa) |
| | B9J08_001346 | Uncharacterized protein. (369 aa) |
| | B9J08_001320 | Uncharacterized protein. (426 aa) |
| | B9J08_001305 | Structural maintenance of chromosomes protein. (1418 aa) |
| | B9J08_001075 | Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. (2844 aa) |
| | B9J08_001192 | Uncharacterized protein. (1661 aa) |
| | B9J08_001173 | NAD-dependent protein deacetylase; Belongs to the sirtuin family. Class I subfamily. (351 aa) |
| | B9J08_001141 | Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. (1176 aa) |
| | B9J08_004862 | Chromatin modification-related protein. (259 aa) |
| | B9J08_004576 | Uncharacterized protein. (2067 aa) |
| | B9J08_001096 | GATA-type domain-containing protein. (764 aa) |
| | B9J08_001093 | Protein HIR; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. (983 aa) |
| | B9J08_001066 | WAC domain-containing protein. (1225 aa) |
| | B9J08_005517 | Uncharacterized protein. (765 aa) |
| | B9J08_004747 | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (504 aa) |
| | B9J08_004669 | CBFD_NFYB_HMF domain-containing protein. (243 aa) |
| | B9J08_004670 | Uncharacterized protein. (1155 aa) |
| | B9J08_004571 | RFX-type winged-helix domain-containing protein. (621 aa) |
| | B9J08_005356 | Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation. (1054 aa) |
| | B9J08_005252 | Uncharacterized protein. (699 aa) |
| | B9J08_005240 | RXT2_N domain-containing protein. (334 aa) |
| | B9J08_005354 | Uncharacterized protein. (378 aa) |
| | B9J08_005310 | DNA_MISMATCH_REPAIR_2 domain-containing protein; Component of the post-replicative DNA mismatch repair system (MMR). (989 aa) |
| | B9J08_004959 | FK506-binding protein. (426 aa) |
| | B9J08_005507 | Uncharacterized protein. (1080 aa) |
| | B9J08_005186 | 26S protease regulatory subunit 8; Belongs to the AAA ATPase family. (400 aa) |
| | B9J08_005442 | WD_REPEATS_REGION domain-containing protein. (389 aa) |
| | B9J08_005145 | Histone H2B; Belongs to the histone H2B family. (130 aa) |
| | B9J08_005443 | Uncharacterized protein. (238 aa) |
| | B9J08_005370 | YL1_C domain-containing protein. (861 aa) |
| | B9J08_005361 | Uncharacterized protein. (268 aa) |
| | B9J08_005366 | Uncharacterized protein; Belongs to the actin family. (771 aa) |
| | B9J08_005341 | Cnd3 domain-containing protein. (1145 aa) |
| | B9J08_005325 | Uncharacterized protein. (861 aa) |
| | B9J08_005241 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (259 aa) |
| | B9J08_005234 | Uncharacterized protein. (1113 aa) |
| | B9J08_005192 | PAPA-1 domain-containing protein. (280 aa) |
| | B9J08_005157 | Uncharacterized protein. (496 aa) |
| | B9J08_001303 | Uncharacterized protein. (636 aa) |
| | B9J08_005133 | Histone acetyltransferase GCN5. (522 aa) |
| | B9J08_005121 | HMG box domain-containing protein. (452 aa) |
| | B9J08_005074 | MRG domain-containing protein. (336 aa) |
| | B9J08_005071 | E3 ubiquitin-protein ligase. (780 aa) |
| | B9J08_004932 | RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. (474 aa) |
| | B9J08_004684 | PHD-type domain-containing protein. (641 aa) |
| | B9J08_005550 | Uncharacterized protein. (881 aa) |
| | B9J08_001302 | E3 ubiquitin protein ligase. (676 aa) |
| | B9J08_002224 | FACT complex subunit SPT16. (1031 aa) |
| | B9J08_000562 | Uncharacterized protein. (551 aa) |
| | B9J08_001566 | Uncharacterized protein. (1201 aa) |
| | B9J08_001288 | Uncharacterized protein. (438 aa) |
| | B9J08_001349 | SCA7 domain-containing protein. (493 aa) |
| | B9J08_001603 | Uncharacterized protein. (347 aa) |
| | B9J08_001813 | Uncharacterized protein. (1010 aa) |
| | B9J08_002353 | Uncharacterized protein. (202 aa) |
| | B9J08_001735 | Uncharacterized protein. (372 aa) |
| | B9J08_001692 | AAA_16 domain-containing protein. (437 aa) |
| | B9J08_001681 | ORC_WH_C domain-containing protein. (729 aa) |
| | B9J08_001649 | Protein HIR; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. (959 aa) |
| | B9J08_001601 | N-acetyltransferase domain-containing protein. (247 aa) |
| | B9J08_001587 | Zf-primase domain-containing protein. (595 aa) |
| | B9J08_001557 | Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family. (1441 aa) |
| | B9J08_002162 | Uncharacterized protein. (461 aa) |
| | B9J08_002111 | Bromo domain-containing protein. (466 aa) |
