node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
B9J08_000045 | B9J08_005145 | A0A2H1A6V1 | A0A2H0ZDN4 | ISWI chromatin-remodeling complex ATPase ISW2. | Histone H2B; Belongs to the histone H2B family. | 0.785 |
B9J08_000620 | B9J08_000632 | A0A2H1A6B8 | A0A2H1A5H8 | FHA domain-containing protein. | Ubiquitin-40S ribosomal protein S27a. | 0.699 |
B9J08_000620 | B9J08_001075 | A0A2H1A6B8 | A0A2H1A1C6 | FHA domain-containing protein. | Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. | 0.507 |
B9J08_000620 | B9J08_004166 | A0A2H1A6B8 | A0A2H0ZI66 | FHA domain-containing protein. | AAA_23 domain-containing protein. | 0.419 |
B9J08_000620 | B9J08_004769 | A0A2H1A6B8 | A0A2H0ZHI4 | FHA domain-containing protein. | Polyubiquitin. | 0.544 |
B9J08_000620 | B9J08_005411 | A0A2H1A6B8 | A0A2H0ZDK4 | FHA domain-containing protein. | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. | 0.419 |
B9J08_000632 | B9J08_000620 | A0A2H1A5H8 | A0A2H1A6B8 | Ubiquitin-40S ribosomal protein S27a. | FHA domain-containing protein. | 0.699 |
B9J08_000632 | B9J08_001075 | A0A2H1A5H8 | A0A2H1A1C6 | Ubiquitin-40S ribosomal protein S27a. | Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. | 0.597 |
B9J08_000632 | B9J08_002167 | A0A2H1A5H8 | A0A2H1A0C1 | Ubiquitin-40S ribosomal protein S27a. | Uncharacterized protein. | 0.699 |
B9J08_000632 | B9J08_004336 | A0A2H1A5H8 | A0A2H0ZIM9 | Ubiquitin-40S ribosomal protein S27a. | Uncharacterized protein; Belongs to the protein kinase superfamily. | 0.416 |
B9J08_000632 | B9J08_004616 | A0A2H1A5H8 | A0A2H0ZGW5 | Ubiquitin-40S ribosomal protein S27a. | UBX domain-containing protein. | 0.634 |
B9J08_000632 | B9J08_004769 | A0A2H1A5H8 | A0A2H0ZHI4 | Ubiquitin-40S ribosomal protein S27a. | Polyubiquitin. | 0.999 |
B9J08_000632 | B9J08_005145 | A0A2H1A5H8 | A0A2H0ZDN4 | Ubiquitin-40S ribosomal protein S27a. | Histone H2B; Belongs to the histone H2B family. | 0.842 |
B9J08_000632 | B9J08_005411 | A0A2H1A5H8 | A0A2H0ZDK4 | Ubiquitin-40S ribosomal protein S27a. | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. | 0.618 |
B9J08_001075 | B9J08_000620 | A0A2H1A1C6 | A0A2H1A6B8 | Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. | FHA domain-containing protein. | 0.507 |
B9J08_001075 | B9J08_000632 | A0A2H1A1C6 | A0A2H1A5H8 | Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. | Ubiquitin-40S ribosomal protein S27a. | 0.597 |
B9J08_001075 | B9J08_002167 | A0A2H1A1C6 | A0A2H1A0C1 | Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. | Uncharacterized protein. | 0.507 |
B9J08_001075 | B9J08_003814 | A0A2H1A1C6 | A0A2H0ZNK0 | Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. | 0.732 |
B9J08_001075 | B9J08_003829 | A0A2H1A1C6 | A0A2H0ZNL4 | Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. | Serine/threonine-protein kinase RAD53; Controls S-phase checkpoint as well as G1 and G2 DNA damage checkpoints. Phosphorylates proteins on serine, threonine, and tyrosine. Prevents entry into anaphase and mitotic exit after DNA damage via regulation of the Polo kinase CDC5. | 0.885 |
B9J08_001075 | B9J08_004166 | A0A2H1A1C6 | A0A2H0ZI66 | Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. | AAA_23 domain-containing protein. | 0.955 |