30 items (Verticillium dahliae) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

Your Input:
	VDAG_00571	Inositol-1-monophosphatase. (298 aa)
	VDAG_00573	Uncharacterized protein. (212 aa)
	VDAG_00599	Histidinol-phosphate aminotransferase. (415 aa)
	VDAG_00021	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. (552 aa)
	VDAG_00041	Inositol-3-phosphate synthase. (503 aa)
	VDAG_00068	Pentafunctional AROM polypeptide. (756 aa)
	VDAG_01254	Tryptophan synthase. (714 aa)
	VDAG_01266	DNA repair protein RAD16. (1004 aa)
	VDAG_03428	Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (439 aa)
	VDAG_03864	Bifunctional polynucleotide phosphatase/kinase. (422 aa)
	VDAG_04453	Phospho-2-dehydro-3-deoxyheptonate aldolase. (379 aa)
	VDAG_04085	Sphingolipid long chain base-responsive protein PIL1. (381 aa)
	VDAG_04743	Anthranilate synthase component 1. (227 aa)
	VDAG_04769	Phospho-2-dehydro-3-deoxyheptonate aldolase. (249 aa)
	VDAG_05738	Multifunctional tryptophan biosynthesis protein; Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities. (773 aa)
	VDAG_06548	HET domain-containing protein. (929 aa)
	VDAG_06549	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. (262 aa)
	VDAG_06820	Phospho-2-dehydro-3-deoxyheptonate aldolase; Belongs to the class-II DAHP synthase family. (470 aa)
	VDAG_06876	Histidine biosynthesis trifunctional protein. (851 aa)
	VDAG_07049	Anthranilate synthase component 1. (521 aa)
	VDAG_07695	Chorismate synthase. (408 aa)
	VDAG_07820	Anthranilate phosphoribosyltransferase. (414 aa)
	VDAG_08172	Inositol-1-monophosphatase. (336 aa)
	qutE	Catabolic 3-dehydroquinase; Is involved in the catabolism of quinate. Allows the utilization of quinate as carbon source via the beta-ketoadipate pathway; Belongs to the type-II 3-dehydroquinase family. (153 aa)
	VDAG_08175	Quinate dehydrogenase. (324 aa)
	VDAG_08289	3-dehydroquinate synthase. (474 aa)
	VDAG_08484	Imidazoleglycerol-phosphate dehydratase; Belongs to the imidazoleglycerol-phosphate dehydratase family. (229 aa)
	VDAG_08760	ATP phosphoribosyltransferase. (339 aa)
	VDAG_10038	3-phosphoshikimate 1-carboxyvinyltransferase; The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis. In the 2nd section; belongs to the EPSP synthase family. In the 4th section; belongs to the type-I 3-dehydroquinase family. In the N-terminal section; belongs to the dehydroquinate synthase family. (1574 aa)
	VDAG_10439	Histidinol-phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. (311 aa)

Your Current Organism:

Verticillium dahliae

NCBI taxonomy Id: 498257
Other names: V. dahliae VdLs.17, Verticillium dahliae VdLs.17

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
VDAG_00021	VDAG_00571	G2WR38	G2WQC9	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.	Inositol-1-monophosphatase.	0.566
VDAG_00021	VDAG_00573	G2WR38	G2WQD1	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.	Uncharacterized protein.	0.566
VDAG_00021	VDAG_00599	G2WR38	G2WQF7	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.	Histidinol-phosphate aminotransferase.	0.996
VDAG_00021	VDAG_01254	G2WR38	G2WTY1	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.	Tryptophan synthase.	0.808
VDAG_00021	VDAG_01266	G2WR38	G2WTZ3	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.	DNA repair protein RAD16.	0.907
VDAG_00021	VDAG_03428	G2WR38	G2WZI6	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.	Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.	0.999
VDAG_00021	VDAG_03864	G2WR38	G2X0T5	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.	Bifunctional polynucleotide phosphatase/kinase.	0.956
VDAG_00021	VDAG_04743	G2WR38	G2X406	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.	Anthranilate synthase component 1.	0.451
VDAG_00021	VDAG_05738	G2WR38	G2X6F6	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.	Multifunctional tryptophan biosynthesis protein; Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities.	0.861
VDAG_00021	VDAG_06548	G2WR38	G2X7U0	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.	HET domain-containing protein.	0.960
VDAG_00021	VDAG_06549	G2WR38	G2X7U1	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase.	0.995
VDAG_00021	VDAG_06876	G2WR38	G2X9P4	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.	Histidine biosynthesis trifunctional protein.	0.999
VDAG_00021	VDAG_07049	G2WR38	G2XAE6	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.	Anthranilate synthase component 1.	0.451
VDAG_00021	VDAG_07820	G2WR38	G2XCD8	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.	Anthranilate phosphoribosyltransferase.	0.679
VDAG_00021	VDAG_08172	G2WR38	G2XDE0	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.	Inositol-1-monophosphatase.	0.566
VDAG_00021	VDAG_08484	G2WR38	G2XEA2	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.	Imidazoleglycerol-phosphate dehydratase; Belongs to the imidazoleglycerol-phosphate dehydratase family.	0.999
VDAG_00021	VDAG_08760	G2WR38	G2XF28	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.	ATP phosphoribosyltransferase.	0.996
VDAG_00021	VDAG_10439	G2WR38	G2XJV7	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.	Histidinol-phosphatase; Belongs to the PHP hydrolase family. HisK subfamily.	0.685
VDAG_00041	VDAG_00571	G2WR58	G2WQC9	Inositol-3-phosphate synthase.	Inositol-1-monophosphatase.	0.973
VDAG_00041	VDAG_00573	G2WR58	G2WQD1	Inositol-3-phosphate synthase.	Uncharacterized protein.	0.690