(10 nodes) Histidine metabolic process network (Verticillium dahliae)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Your Input:
	VDAG_00599	Histidinol-phosphate aminotransferase. (415 aa)
	VDAG_00021	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. (552 aa)
	VDAG_01266	DNA repair protein RAD16. (1004 aa)
	VDAG_03428	Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (439 aa)
	VDAG_03864	Bifunctional polynucleotide phosphatase/kinase. (422 aa)
	VDAG_06548	HET domain-containing protein. (929 aa)
	VDAG_06549	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. (262 aa)
	VDAG_06876	Histidine biosynthesis trifunctional protein. (851 aa)
	VDAG_08484	Imidazoleglycerol-phosphate dehydratase; Belongs to the imidazoleglycerol-phosphate dehydratase family. (229 aa)
	VDAG_08760	ATP phosphoribosyltransferase. (339 aa)

Your Current Organism:

Verticillium dahliae

NCBI taxonomy Id: 498257
Other names: V. dahliae VdLs.17, Verticillium dahliae VdLs.17

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
VDAG_00021	VDAG_00599	G2WR38	G2WQF7	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.	Histidinol-phosphate aminotransferase.	0.996
VDAG_00021	VDAG_01266	G2WR38	G2WTZ3	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.	DNA repair protein RAD16.	0.907
VDAG_00021	VDAG_03428	G2WR38	G2WZI6	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.	Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.	0.999
VDAG_00021	VDAG_03864	G2WR38	G2X0T5	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.	Bifunctional polynucleotide phosphatase/kinase.	0.956
VDAG_00021	VDAG_06548	G2WR38	G2X7U0	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.	HET domain-containing protein.	0.960
VDAG_00021	VDAG_06549	G2WR38	G2X7U1	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase.	0.995
VDAG_00021	VDAG_06876	G2WR38	G2X9P4	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.	Histidine biosynthesis trifunctional protein.	0.999
VDAG_00021	VDAG_08484	G2WR38	G2XEA2	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.	Imidazoleglycerol-phosphate dehydratase; Belongs to the imidazoleglycerol-phosphate dehydratase family.	0.999
VDAG_00021	VDAG_08760	G2WR38	G2XF28	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.	ATP phosphoribosyltransferase.	0.996
VDAG_00599	VDAG_00021	G2WQF7	G2WR38	Histidinol-phosphate aminotransferase.	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.	0.996
VDAG_00599	VDAG_01266	G2WQF7	G2WTZ3	Histidinol-phosphate aminotransferase.	DNA repair protein RAD16.	0.921
VDAG_00599	VDAG_03428	G2WQF7	G2WZI6	Histidinol-phosphate aminotransferase.	Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.	0.999
VDAG_00599	VDAG_03864	G2WQF7	G2X0T5	Histidinol-phosphate aminotransferase.	Bifunctional polynucleotide phosphatase/kinase.	0.964
VDAG_00599	VDAG_06548	G2WQF7	G2X7U0	Histidinol-phosphate aminotransferase.	HET domain-containing protein.	0.899
VDAG_00599	VDAG_06549	G2WQF7	G2X7U1	Histidinol-phosphate aminotransferase.	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase.	0.899
VDAG_00599	VDAG_06876	G2WQF7	G2X9P4	Histidinol-phosphate aminotransferase.	Histidine biosynthesis trifunctional protein.	0.997
VDAG_00599	VDAG_08484	G2WQF7	G2XEA2	Histidinol-phosphate aminotransferase.	Imidazoleglycerol-phosphate dehydratase; Belongs to the imidazoleglycerol-phosphate dehydratase family.	0.999
VDAG_00599	VDAG_08760	G2WQF7	G2XF28	Histidinol-phosphate aminotransferase.	ATP phosphoribosyltransferase.	0.988
VDAG_01266	VDAG_00021	G2WTZ3	G2WR38	DNA repair protein RAD16.	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.	0.907
VDAG_01266	VDAG_00599	G2WTZ3	G2WQF7	DNA repair protein RAD16.	Histidinol-phosphate aminotransferase.	0.921